Prescription Patterns of Antidementia and Psychotropic Drugs in People Living With Dementia: Findings From the Clinical Pathway Study of Alzheimer's Disease in China

Author(s):  
Yingyang Zhang ◽  
Hao Luo ◽  
Gloria H.Y. Wong ◽  
Mei Zhao ◽  
Xiaozhen Lv ◽  
...  
2015 ◽  
Vol 28 (2) ◽  
pp. 211-219 ◽  
Author(s):  
Mei Zhao ◽  
Xiaozhen Lv ◽  
Maimaitirexiati Tuerxun ◽  
Jincai He ◽  
Benyan Luo ◽  
...  

ABSTRACTBackground:The prevalence and factors associated with delays in help seeking for people with dementia in China are unknown.Methods:Within 1,010 consecutively registered participants in the Clinical Pathway for Alzheimer's Disease in China (CPAD) study (NCT01779310), 576 persons with dementia (PWDs) and their informants reported the estimated time from symptom onset to first medical visit seeking diagnosis. Univariate analysis of general linear model was used to examine the potential factors associated with the delayed diagnosis seeking.Results:The median duration from the first noticeable symptom to the first visit seeking diagnosis or treatment was 1.77 years. Individuals with a positive family history of dementia had longer duration (p= 0.05). Compared with other types of dementia, people with vascular dementia (VaD) were referred for diagnosis earliest, and the sequence for such delays was: VaD < Alzheimer's disease (AD) < frontotemporal dementia (FTD) (p< 0.001). Subtypes of dementia (p< 0.001), family history (p= 0.01), and education level (p= 0.03) were associated with the increased delay in help seeking.Conclusions:In China, seeking diagnosis for PWDs is delayed for approximately 2 years, even in well-established memory clinics. Clinical features, family history, and less education may impede help seeking in dementia care.


2014 ◽  
Vol 15 (7) ◽  
pp. 497-503 ◽  
Author(s):  
Laia Calvó-Perxas ◽  
Oriol Turró-Garriga ◽  
Maria Aguirregomozcorta ◽  
Josep Bisbe ◽  
Erélido Hernández ◽  
...  

2015 ◽  
Vol 11 (7S_Part_11) ◽  
pp. P526-P526
Author(s):  
Ki Jung Chang ◽  
Sang Joon Son ◽  
Dongsoo Kim ◽  
Kang Soo Lee ◽  
Hyung Woong Roh ◽  
...  

1991 ◽  
Vol 158 (3) ◽  
pp. 351-357 ◽  
Author(s):  
R. Hunter ◽  
D. J. Wyper ◽  
J. Patterson ◽  
M. T. Hansen ◽  
G. M. Goodwin

The effects of physostigmine on patterns of rCBF in patients with pre-senile Alzheimer's disease were studied using 99mTc-labelled HMPAO SPECT. Regional CBF increased in the left cortex relative to right, with the most significant effect in left frontal and higher frontal regions. Measures of regional brain function, such as SPECT, are an important complement to psychological test batteries in understanding the effects in brain of putative antidementia drugs. SPECT brain imaging could extend our understanding of the action of psychotropic drugs in other major psychiatric illnesses.


2016 ◽  
Vol 6 (1) ◽  
pp. 25-37 ◽  
Author(s):  
Kimiko Kadohara ◽  
Izumi Sato ◽  
Yuko Doi ◽  
Masaru Arai ◽  
Yosuke Fujii ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document