scholarly journals Identification of amino acid substitutions in avian influenza virus (H5N1) matrix protein 1 by using nanoelectrospray MS and MS/MS

2009 ◽  
Vol 20 (2) ◽  
pp. 312-320 ◽  
Author(s):  
Ning Liu ◽  
Wenjun Song ◽  
Kim-Chung Lee ◽  
Pui Wang ◽  
Honglin Chen ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Amino Acid ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Matrix Protein ◽  
Amino Acid Substitutions ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

Expression of Avian Influenza Virus (H5N1) Hemagglutinin and Matrix Protein 1 in Pichia pastoris and Evaluation of their Immunogenicity in Mice

2014 ◽  
Vol 172 (7) ◽  
pp. 3635-3645 ◽  
Author(s):  
M. Subathra ◽  
P. Santhakumar ◽  
Sureddi Satyam Naidu ◽  
M. Lakshmi Narasu ◽  
T. M. A. Senthilkumar ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Pichia Pastoris ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Matrix Protein ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

scholarly journals Characterization of H9N2 influenza A viruses isolated from chicken products imported into Japan from China

2006 ◽  
Vol 135 (3) ◽  
pp. 386-391 ◽  
Author(s):  
M. MASE ◽  
M. ETO ◽  
K. IMAI ◽  
K. TSUKAMOTO ◽  
S. YAMAGUCHI
Keyword(s):  
Influenza Virus ◽  
Amino Acid ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Influenza A ◽  
H9n2 Virus ◽  
Amino Acid Substitutions ◽  
Influenza A Viruses ◽  
Potential Sources

We characterized eleven H9N2 influenza A viruses isolated from chicken products imported from China. Genetically they were classified into six distinct genotypes, including five already known genotypes and one novel genotype. This suggested that such multiple genotypes of the H9N2 virus have possibly already become widespread and endemic in China. Two isolates have amino-acid substitutions that confer resistance to amantadine in the M2 region, and this supported the evidence that this mutation might be a result of the wide application of amantadine for avian influenza treatment in China. These findings emphasize the importance of surveillance for avian influenza virus in this region, and of quarantining imported chicken products as potential sources for the introduction of influenza virus.

scholarly journals Experimental Infection and Natural Contact Exposure of Dogs with Avian Influenza Virus (H5N1)

2008 ◽  
Vol 14 (2) ◽  
pp. 308-310 ◽  
Author(s):  
Matthias Giese ◽  
Timm C. Harder ◽  
Jens P. Teifke ◽  
Robert Klopfleisch ◽  
Angele Breithaupt ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Experimental Infection ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1 ◽  
Contact Exposure

scholarly journals Pathology of clade 2.3.2.1 avian influenza virus (H5N1) infection in quails and ducks in Bangladesh

2018 ◽  
Vol 48 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Mohammed Nooruzzaman ◽  
Md. Enamul Haque ◽  
Emdadul Haque Chowdhury ◽  
Mohammad Rafiqul Islam
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
H5n1 Infection ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

scholarly journals Two-dimensional antigenic dendrogram and phylogenetic tree of avian influenza virus H5N1

2011 ◽  
Vol 64 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Alexander C.K. Lai ◽  
Wai-lan Wu ◽  
Siu-ying Lau ◽  
Yi Guan ◽  
Honglin Chen
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Phylogenetic Tree ◽  
Avian Influenza Virus ◽  
Two Dimensional ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

scholarly journals Chronic Heat Stress Weakened the Innate Immunity and Increased the Virulence of Highly Pathogenic Avian Influenza Virus H5N1 in Mice

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Yi Jin ◽  
Yanxin Hu ◽  
Deping Han ◽  
Ming Wang
Keyword(s):  
Innate Immunity ◽  
Influenza Virus ◽  
Heat Stress ◽  
Avian Influenza ◽  
Respiratory Tract ◽  
Avian Influenza Virus ◽  
Mrna Levels ◽  
Local Immunity ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

Chronic heat stress (CHS) can negatively affect immune response in animals. In this study we assessed the effects of CHS on host innate immunity and avian influenza virus H5N1 infection in mice. Mice were divided into two groups: CHS and thermally neutral (TN). The CHS treatment group exhibited reduced local immunity in the respiratory tract, including the number of pulmonary alveolar macrophages and lesions in the nasal mucosa, trachea, and lungs. Meanwhile, CHS retarded dendritic cells (DCs) maturation and reduced the mRNA levels of IL-6 and IFN-βsignificantly (P<.05). After the CHS treatment, mice were infected with H5N1 virus. The mortality rate and viral load in the lungs of CHS group were higher than those of TN group. The results suggest that the CHS treatment could suppress local immunity in the respiratory tract and innate host immunity in mice significantly and moderately increased the virulence in H5N1-infected mice.

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