scholarly journals Micro-computed tomography assisted distal femur metaphyseal blunt punch compression for determining trabecular bone strength in mice

2016 ◽  
Vol 49 (7) ◽  
pp. 1233-1237 ◽  
Author(s):  
Uma Sankar ◽  
Zachary J. Pritchard ◽  
Michael J. Voor
2013 ◽  
Author(s):  
Agnes Ostertag ◽  
Francoise Peyrin ◽  
Sylvie Fernandez ◽  
Jean-Denis Laredo ◽  
Vernejoul Marie-Christine De ◽  
...  

2014 ◽  
Vol 695 ◽  
pp. 588-591
Author(s):  
Khairul Salleh Basaruddin ◽  
Ruslizam Daud

This study aims to investigate the influence of trabecular bone in human mandible bone on the mechanical response under implant load. Three dimensional voxel finite element (FE) model of mandible bone was reconstructed from micro-computed tomography (CT) images that were captured from bone specimen. Two FE models were developed where the first consists of cortical bone, trabecular bone and implants, and trabecular bone part was excluded in the second model. A static analysis was conducted on both models using commercial software Voxelcon. The results suggest that trabecular bone contributed to the strength of human mandible bone and to the effectiveness of load distribution under implant load.


PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5156 ◽  
Author(s):  
Leoni Georgiou ◽  
Tracy L. Kivell ◽  
Dieter H. Pahr ◽  
Matthew M. Skinner

BackgroundIn addition to external bone shape and cortical bone thickness and distribution, the distribution and orientation of internal trabecular bone across individuals and species has yielded important functional information on how bone adapts in response to load. In particular, trabecular bone analysis has played a key role in studies of human and nonhuman primate locomotion and has shown that species with different locomotor repertoires display distinct trabecular architecture in various regions of the skeleton. In this study, we analyse trabecular structure throughout the distal femur of extant hominoids and test for differences due to locomotor loading regime.MethodsMicro-computed tomography scans ofHomo sapiens(n= 11),Pan troglodytes(n= 18),Gorilla gorilla(n= 14) andPongosp. (n= 7) were used to investigate trabecular structure throughout the distal epiphysis of the femur. We predicted that bone volume fraction (BV/TV) in the medial and lateral condyles inHomowould be distally concentrated and more anisotropic due to a habitual extended knee posture at the point of peak ground reaction force during bipedal locomotion, whereas great apes would show more posteriorly concentrated BV/TV and greater isotropy due to a flexed knee posture and more variable hindlimb use during locomotion.ResultsResults indicate some significant differences between taxa, with the most prominent being higher BV/TV in the posterosuperior region of the condyles inPanand higher BV/TV and anisotropy in the posteroinferior region inHomo. Furthermore, trabecular number, spacing and thickness differ significantly, mainly separatingGorillafrom the other apes.DiscussionThe trabecular architecture of the distal femur holds a functional signal linked to habitual behaviour; however, there was more similarity across taxa and greater intraspecific variability than expected. Specifically, there was a large degree of overlap in trabecular structure across the sample, andHomowas not as distinct as predicted. Nonetheless, this study offers a comparative sample of trabecular structure in the hominoid distal femur and can contribute to future studies of locomotion in extinct taxa.


2007 ◽  
Vol 40 (15) ◽  
pp. 3397-3403 ◽  
Author(s):  
Xiang Wang ◽  
Daniel B. Masse ◽  
Huijie Leng ◽  
Kevin P. Hess ◽  
Ryan D. Ross ◽  
...  

2010 ◽  
Vol 21 (3) ◽  
pp. 920-924 ◽  
Author(s):  
Sung-Yoon Won ◽  
Sung-Hyun Kim ◽  
Sung-Tae Kim ◽  
Doo-Jin Paik ◽  
Wu-Chul Song ◽  
...  

2019 ◽  
Vol 48 (2) ◽  
pp. 595-605 ◽  
Author(s):  
S. S. Karhula ◽  
M. A. J. Finnilä ◽  
S. J. O. Rytky ◽  
D. M. Cooper ◽  
J. Thevenot ◽  
...  

Abstract The aim of this study was to quantify sub-resolution trabecular bone morphometrics, which are also related to osteoarthritis (OA), from clinical resolution cone beam computed tomography (CBCT). Samples (n = 53) were harvested from human tibiae (N = 4) and femora (N = 7). Grey-level co-occurrence matrix (GLCM) texture and histogram-based parameters were calculated from CBCT imaged trabecular bone data, and compared with the morphometric parameters quantified from micro-computed tomography. As a reference for OA severity, histological sections were subjected to OARSI histopathological grading. GLCM and histogram parameters were correlated to bone morphometrics and OARSI individually. Furthermore, a statistical model of combined GLCM/histogram parameters was generated to estimate the bone morphometrics. Several individual histogram and GLCM parameters had strong associations with various bone morphometrics (|r| > 0.7). The most prominent correlation was observed between the histogram mean and bone volume fraction (r = 0.907). The statistical model combining GLCM and histogram-parameters resulted in even better association with bone volume fraction determined from CBCT data (adjusted R2 change = 0.047). Histopathology showed mainly moderate associations with bone morphometrics (|r| > 0.4). In conclusion, we demonstrated that GLCM- and histogram-based parameters from CBCT imaged trabecular bone (ex vivo) are associated with sub-resolution morphometrics. Our results suggest that sub-resolution morphometrics can be estimated from clinical CBCT images, associations becoming even stronger when combining histogram and GLCM-based parameters.


2016 ◽  
Vol 42 (1) ◽  
pp. 71-77 ◽  
Author(s):  
G. Xiong ◽  
Z. Xiao ◽  
H. Wang ◽  
S. Guo ◽  
J. Tao

Seventeen fresh lunates with stage III Kienböck’s disease were scanned with micro-computed tomography. Four regions of interest were selected to measure trabecular parameters, which were compared with those from normal lunates. Within the three regions in the distal surface, there was more compact trabecular bone in the middle region when compared with the palmar and dorsal regions. In the central part, the trabeculae of the Kienböck’s lunates were much thicker than those in normal lunates. The diameters of the palmar nutrient foramina of the Kienböck’s lunates were significantly smaller than those in normal lunates. In affected lunates, the bony disruptions were mostly located in the palmar or dorsal areas, which were shown from trabecular bone structure analysis to be structurally weaker. This leads to separation of the distal part of the fractured bone, disruption of the blood supply, poor bone remodelling and proneness to secondary fracture and eventual collapse.


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