Anomalous origins of the right and posterior descending coronary arteries from the left anterior descending coronary artery: Unusual pattern of single coronary artery

Adenosine relaxes the coronary arteries of various species through A2 receptors. The aim of the present investigation was to evaluate the relaxing effects of adenosine in relation to the role of calcium in bovine coronary arteries by studying the vasodilatory effect of adenosine in normal and calcium-free medium and on calcium-45 efflux into calcium-free medium. Acetylcholine (ACh) and norepinephrine (NE) were used to induce tone in coronary artery rings. Adenosine, 5′-(N-ethylcarboxamido)adenosine (NECA), and N6-(L-phenylisopropyl)adenosine (L-PIA) produced concentration-dependent relaxations of the coronary artery rings. Both in normal and calcium-free medium, the order of potency for adenosine analogs (NECA > L-PIA > adenosine) was similar and 8-phenyltheophylline antagonized the relaxation responses to adenosine and its analogs. Removal of extracellular calcium shifted the concentration–response curves to the right in a parallel fashion, slowed the rate of relaxation, and in NE contracted rings reduced the maximum responses for adenosine and its analogs. In calcium-free medium, adenosine was without an effect on calcium-45 efflux in the presence of ACh. However, adenosine inhibited the stimulated calcium-45 efflux induced by NE. The data suggest that the vasodilatory action of adenosine in bovine coronary smooth muscle has both extracellular calcium-dependent and -independent components.Key words: adenosine receptors, calcium, coronary circulation, vascular smooth muscle, acetylcholine, norepinephrine.

Download Full-text

Patient with Acute Coronary Syndrome in the Setting of an Extremely Rare form of Complex Congenital Anomalous Coronaries

Aorta ◽

10.1055/s-0041-1729852 ◽

2021 ◽

Author(s):

Mahmoud Abdelnabi ◽

Fady Gerges ◽

Yehia Saleh ◽

Eman Elsharkawy ◽

Mohamed Sanhoury ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Coronary Artery ◽

Young Patient ◽

Right Coronary Artery ◽

Unusual Case ◽

Single Coronary Artery ◽

Sinus Of Valsalva ◽

Rare Form ◽

Coronary Syndrome ◽

The Right

AbstractA single coronary artery is an exceedingly rare anomaly. Hereby, we present an unusual case of a young patient with an acute coronary syndrome who was found to have a single coronary artery originating from a single ostium in the right sinus of Valsalva with dual left anterior descending (LAD) arteries arising from the right coronary artery with two different anatomical courses, and additionally one of those LADs running a malignant intra-arterial course.

Download Full-text

A Single Coronary Artery with an Absent Right Coronary and a Superdominant Left Circumflex Giving off a Branch Supplying the Right Coronary Artery Territory

Journal of College of Physicians And Surgeons Pakistan ◽

10.29271/jcpsp.2019.12.s80 ◽

2019 ◽

pp. S80-S82

Author(s):

Imran Iftikhar ◽

Adeel Rehman ◽

Hamid Khan

Keyword(s):

Coronary Artery ◽

Right Coronary Artery ◽

Single Coronary Artery ◽

The Right

Download Full-text

Coronary artery conundrum: A single coronary artery with origin of the right coronary artery from the distal left circumflex artery

International Journal of Case Reports and Images ◽

10.5348/100909z01md2018cr ◽

2018 ◽

Vol 9 ◽

pp. 1

Author(s):

George Stoupakis

Keyword(s):

Coronary Artery ◽

Right Coronary Artery ◽

Single Coronary Artery ◽

Circumflex Artery ◽

Left Circumflex Artery ◽

The Right

Download Full-text

Angiographic enigma: A single coronary artery with the right coronary artery originating from the distal left circumflex artery

Heart Views ◽

10.4103/1995-705x.164465 ◽

2015 ◽

Vol 16 (3) ◽

pp. 104 ◽

Cited By ~ 1

Author(s):

Satyajit Singh ◽

MahendraPrasad Tripathy ◽

Giridhari Jena ◽

SanatKumar Sahoo

Keyword(s):

Coronary Artery ◽

Right Coronary Artery ◽

Single Coronary Artery ◽

Circumflex Artery ◽

Left Circumflex Artery ◽

The Right

Download Full-text

Normal values of coronary arteries branching height in women

Reports of Morphology ◽

10.31393/morphology-journal-2021-27(4)-06 ◽

2021 ◽

Vol 27 (4) ◽

pp. 41-46

Author(s):

U.Ye. Pidvalna ◽

D.M. Beshley ◽

M.Z. Mirchuk ◽

L.R. Mateshuk-Vatseba

Keyword(s):

Body Mass Index ◽

Coronary Artery ◽

Body Mass ◽

Coronary Arteries ◽

Body Surface ◽

Left Coronary Artery ◽

Statistical Significance ◽

Lower Edge ◽

The Mean ◽

The Right

Morphometric analysis of the structures of the aortic bulb and coronary arteries is necessary for the planning of cardiac surgery and endovascular interventions. The aim of the study was to determine the height of the coronary arteries branching in healthy women of Lviv city and Lviv region and to determine the relationship between the height of the location of the orifice of the coronary artery with anthropometric indicators. Fifteen computed tomography images with contrast of female thorax without heart and ascending aortic lesions (normal) were selected for the study. The height of the upper and lower edges of the coronary arteries was measured; height of Valsalva sinuses. The comparison of the mean values was performed according to the Student’s t-test. The correlation between the observed variables (age, height, body weight, body mass index, body surface area, height of the sinuses of Valsalva) was calculated using the Pearson linear correlation method (r). According to the study, the population group consisted of persons of the second period of adulthood (46.67 %) and the elderly (53.33 %). According to the body mass index, 80 % were overweight or obese I-II degree. The mean height of the coronary artery orifice in women without structural changes of the heart and ascending aorta was: 11.19±1.96 mm for the left and 11.68±1.80 mm for the right. The height of the orifice of the right and left coronary arteries were almost the same, without statistical significance (p=0.26). Analysis of the correlation between the values of the height of the orifice of the coronary artery did not show a probable dependence on height, weight, age, body mass index and body surface area. There is a direct relationship between the parameters of the height of the lower edge of the right coronary artery and the height of the upper edge of the right coronary artery (r=+0.75, p=0.001) and between the value of the lower edge of the left coronary artery and the upper edge of the left coronary artery (r=+0.63, p=0.01). Thus, the analysis of the correlation between the values of the height of the orifice of the coronary artery in women in norm and anthropometric indicators did not show a significant relationship. There was no statistical significance between the indicators of the height of the orifice of the right and left coronary arteries in women.

Download Full-text

A CADAVERIC STUDY ON CORONARY ARTERY VARIATIONS AND ITS CLINICAL `SIGNIFICANCE

10.36106/ijsr/6023902 ◽

2021 ◽

pp. 20-22

Author(s):

Sony Jhansi Priya ◽

Sangeetha A ◽

M. Sai Krishna

Keyword(s):

Coronary Artery ◽

Coronary Arteries ◽

Left Coronary Artery ◽

Coronary Vessels ◽

Average Diameter ◽

Cadaveric Study ◽

Aortic Sinus ◽

Clinical Procedures ◽

Human Cadavers ◽

The Right

Coronary artery variations are one of the commonest variations observed during clinical procedures. Normally, there are two main coronary arteries, the right coronary artery (RCA), left coronary artery (LCA).Left coronary artery gives two important branches left circumex artery (LCX) and left anterior descending (LAD) arteries. Knowledge about the coronary vessels and its variations are essential to clinicians to prevent untoward injury of vessels during any procedures. To study the morphology and variations of coronar Aim: y arteries by dissection. Materials and Methods: The present study was a cadaveric study which was conducted on 50 hearts obtained from adult human cadavers. Coronary arteries were dissected to see the origin, course and variations. The data was entered in Microsoft excel sheet and expressed in percentage. The Right Results: coronary artery branched out from the right aortic sinus and had an average diameter of 3.5mm. The left coronary artery arouse from left aortic sinus and had an average diameter of 4mm. LMCA divided into two branches in 60 percent, three branches in 30 percent and four branches in 06 percent of the hearts and direct branches from left aortic sinuus in 4 percent hearts.Based on the origin of Posterior descending or interventricular artery, Right dominance was observed in 68 percent, left dominance in 26 percent, and equal dominance in 06 percent of the hearts. Conclusion: Knowledge about the variations of coronary vessels is a prerequisite for clinicians to perform interventions of coronary vessels.

Download Full-text