scholarly journals Determination of β-hydroxy-β-methylbutyrate concentration and enrichment in human plasma using chemical ionization gas chromatography tandem mass spectrometry

2017 ◽  
Vol 1040 ◽  
pp. 233-238 ◽  
Author(s):  
Dillon K. Walker ◽  
John J. Thaden ◽  
Agata Wierzchowska-McNew ◽  
Marielle P.K.J. Engelen ◽  
Nicolaas E.P. Deutz
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Tandem Mass Spectrometry ◽  
Human Plasma ◽  
Chemical Ionization ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry

scholarly journals Multiresidue Determination of Pesticides in Fruit and Vegetables by Gas Chromatography/Tandem Mass Spectrometry

2001 ◽  
Vol 84 (4) ◽  
pp. 1209-1216 ◽  
Author(s):  
Miguel Gamón ◽  
Concha Lleó ◽  
Amparo Ten ◽  
Francisco Mocholí
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Tandem Mass Spectrometry ◽  
Chemical Ionization ◽  
Fruit And Vegetables ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Low Levels ◽  
Multiresidue Determination

Abstract Pesticide residues in fruit and vegetables were determined by gas chromatography/tandem mass spectrometry (GC/MS/MS). Electron impact (EI)/MS/MS and chemical ionization (CI)/MS/MS were developed for 80 compounds, including organochlorine, organophosphorus, organonitrogen, and pyrethroids, providing unambiguous spectral confirmation for these complex matrixes. Residues were extracted from samples with acetone followed by a mixture of dichloromethane–petroleum ether. Two injections per sample were required for analysis of the entire pesticide list by EI/MS/MS and CI/MS/MS.Initial steps involving cleanup and concentration of extracts were eliminated. The excellent selectivity and good linearity allowed quantification and identification of low levels of pesticides in the most difficult matrixes. The method has been used for routine analysis of many vegetables.

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