scholarly journals CRT-100.92 Role Of Tissue Doppler Echocardiography In Predicting The Severity Of Coronary Artery Disease In Patients With Stable Angina Pectoris

2017 ◽  
Vol 10 (3) ◽  
pp. S30
Author(s):  
Mahmoud A. Abdelsamad ◽  
Hatem Abdelrahman ◽  
Amal Soliman ◽  
Yehia Kishk
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Doppler Echocardiography ◽  
Stable Angina ◽  
Tissue Doppler ◽  
Tissue Doppler Echocardiography ◽  
Stable Angina Pectoris ◽  
Artery Disease

scholarly journals Gelatinases A and B activities in the serum of patients with various coronary artery disease stages

2010 ◽  
Vol 67 (10) ◽  
pp. 825-830 ◽  
Author(s):  
Sandra Radenkovic ◽  
Milan Brajovic ◽  
Gordana Konjevic ◽  
Kristina Gopcevic
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Stable Angina ◽  
Stable Angina Pectoris ◽  
Pathogenic Role ◽  
Image System ◽  
Artery Disease ◽  
Disease Stages

Background/Aim. The main characteristic of matrix metalloproteinases (MMPs) is the degradation of extracellular matrix. Synthesis of MMPs has been reported in coronary atherosclerotic lesions in patients with coronary disease (CD) suggesting a pathogenic role of MMPs in its development. Recently there is increasing evidence that gelatinase A (pro MMP-2) and gelatinase B (proMMP-9) play a pathogenic role in the development of the atherosclerotic plaques. The aim of the study was to determine, by the use of a gel image system, a possible presence of active gelatinases in the serum of the patients with CD, as well as if their activity is higher in these patients than in healthy people. Methods. By gelatin zymography we analyzed the activity of proMMP-2 and proMMP-9 in the serum of 50 patients with various coronary artery disease stages and in the serum of 15 healthy controls. The activity was measured by using a gel image system (Kodak Image 1D 3.6.). Results. ProMMP-2 and proMMP-9 activity was significantly higher in the serum of patients with CD compared to controls. There was higher activity of MMP-2 and MMP-9 in the serum of patients with acute myocardial infarction (AMI) compared to patients with stable angina pectoris, as well as higher proMMP-9 activity in patients with unstable angina pectoris compared to patients with stable angina pectoris. Conclusion. ProMMP-2 and proMMP-9 participate in processes associated with destabilizing plaques and understanding the processes of MMPs activation and regulation may have significant benefits in clinical interpretation. The reported higher proMMP-2 and proMMP-9 activity in the serum of patients with CD suggests a role of proMMP-2 and proMMP-9 in prognostic stratification of these patients and in designing new drugs.

scholarly journals Changes in blood rheology in patients with stable angina pectoris as a result of coronary artery disease.

Circulation ◽  
1987 ◽  
Vol 76 (1) ◽  
pp. 15-20 ◽  
Author(s):  
C Rainer ◽  
D T Kawanishi ◽  
P A Chandraratna ◽  
R M Bauersachs ◽  
C L Reid ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Stable Angina ◽  
Blood Rheology ◽  
Stable Angina Pectoris ◽  
Artery Disease

Relationship between mild renal dysfunction and coronary artery disease in young patients with stable angina pectoris

2020 ◽  
Author(s):  
Mustafa Duran ◽  
Deniz Elcik ◽  
Mehmet T Inanc ◽  
Mikail Yarlıoglues ◽  
Ibrahim E Celik ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Renal Dysfunction ◽  
Stable Angina ◽  
Control Group ◽  
Stable Angina Pectoris ◽  
Number Of Patients ◽  
Study Results ◽  
Artery Disease

Aim: We investigated the relationship between mild renal dysfunction (MRD) and the presence of coronary artery disease (CAD) in people under 60. Materials & methods: A total of 634 (317 patients with vessel stenosis ≥50% and 317 with normal angiography) individuals diagnosed with stable angina pectoris and estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m2 were included in the present study. Results: The mean eGFR was lower (95.3 ± 23.7 vs 109.7 ± 22.3, respectively, p = 0.002) and the number of patients with MRD was higher in patients with CAD (137, 43.2%) than in the control group (52, 16.4%, p < 0.001). The multivariate analysis showed that lower eGFR is an independent risk factor for presence of CAD in people under 60 with stable angina pectoris. Conclusion: According to our retrospective study, the risk of developing CAD appears to be slightly increased in individuals under 60 with MRD.

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