Protein-like particles through nanoprecipitation of mixtures of polymers of opposite charge

2022 ◽  
Vol 607 ◽  
pp. 1786-1795
Author(s):  
Antoine Combes ◽  
Khanh-Nam Tang ◽  
Andrey S. Klymchenko ◽  
Andreas Reisch
Keyword(s):  
2016 ◽  
Vol 113 (26) ◽  
pp. 7160-7165 ◽  
Author(s):  
Oliver J. Harrison ◽  
Julia Brasch ◽  
Gorka Lasso ◽  
Phinikoula S. Katsamba ◽  
Goran Ahlsen ◽  
...  

Desmosomes are intercellular adhesive junctions that impart strength to vertebrate tissues. Their dense, ordered intercellular attachments are formed by desmogleins (Dsgs) and desmocollins (Dscs), but the nature of trans-cellular interactions between these specialized cadherins is unclear. Here, using solution biophysics and coated-bead aggregation experiments, we demonstrate family-wise heterophilic specificity: All Dsgs form adhesive dimers with all Dscs, with affinities characteristic of each Dsg:Dsc pair. Crystal structures of ectodomains from Dsg2 and Dsg3 and from Dsc1 and Dsc2 show binding through a strand-swap mechanism similar to that of homophilic classical cadherins. However, conserved charged amino acids inhibit Dsg:Dsg and Dsc:Dsc interactions by same-charge repulsion and promote heterophilic Dsg:Dsc interactions through opposite-charge attraction. These findings show that Dsg:Dsc heterodimers represent the fundamental adhesive unit of desmosomes and provide a structural framework for understanding desmosome assembly.


ChemInform ◽  
2010 ◽  
Vol 33 (19) ◽  
pp. no-no
Author(s):  
Igor Shevchenko ◽  
Vasyl Andrushko ◽  
Enno Lork ◽  
Gerd-Volker Roeschenthaler

Soft Matter ◽  
2014 ◽  
Vol 10 (36) ◽  
pp. 7088-7095 ◽  
Author(s):  
Rémi Deleurence ◽  
Caroline Parneix ◽  
Cécile Monteux

Using mixtures of latex and surfactant of opposite charges we decouple the effect of the charge and contact angle of the particles on the interface stabilization. We find that the key-parameters are the flocculation state of the particles and the shear energy used to produce the foams.


2020 ◽  
Author(s):  
Chang Li ◽  
Ke Zhang ◽  
Jin-Song Hu

Using in situ liquid cell TEM imaging, the dynamic process of dimer and trimer formation were captured. The kinetic energy of NPs and the NC- Electrostatic Shielding Length (NC-ESL) are...


2005 ◽  
Vol 14 (10) ◽  
pp. 1793-1811 ◽  
Author(s):  
DONATO BINI ◽  
ANDREA GERALICO ◽  
FERNANDO DE FELICE

The behavior of charged spinning test particles moving along circular orbits in the equatorial plane of the Reissner–Nordström space–time is studied in the framework of the Dixon–Souriau model completed with standard choices of supplementary conditions. The gravitomagnetic "clock effect," i.e. the delay in the arrival times of two oppositely circulating particles as measured by a static observer, is derived and discussed in the cases in which the particles have equal/opposite charge and spin, the latter being directed along the z-axis.


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