Retinal angiography and colour Doppler of retrobulbar vessels in Takayasu arteritis

2014 ◽  
Vol 49 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Kimble Teixeira Fonseca Matos ◽  
Tiago Arantes ◽  
Alexandre Wagner Silva Souza ◽  
Maria Helena Mandello Carvalhaes Ramos ◽  
Norma Allemann ◽  
...  
Author(s):  
Debanjali Sinha ◽  
Sumantro Mondal ◽  
Arijit Nag ◽  
Debasish Lahiri ◽  
Alakendu Ghosh

Background: The objective of the present study was to monitor the disease activity of Takayasu arteritis clinically by the Indian Takayasu Activity Score 2010 (ITAS) and ultra sonographically by Colour Doppler Ultrasound-Kolkata (CDUS-K) Score after 12months of treatment with methotrexate and steroid, and to find the correlation between these two scores.Methods: Around 25 Angiographically proven Takayasu arteritis patients were treated with Methotrexate (15mg weekly) and Steroids (1mg/kg/day for 6weeks and then tapered) for 12months. Wilcoxon matched pair signed rank test was done to assess the change in ITAS 2010 with treatment. A correlation study was done between ITAS 2010 and change in CDUS-K scores at the end of 12months.Results: By Wilcoxon’s matched pair signed rank test, a non-significant change of ITAS 2010 (p=0.066) was observed at the end of 12months, which means that the treatment helps to control the disease progression by preventing a significant increase in ITAS 2010. Strong correlation (correlation coefficient of 0.878, 95% CI = 0.602 to 1.000) was found between the ITAS 2010 and change in CDUS-K scores at 12months follow up.Conclusions: The combination of Methotrexate and steroids helps to control the disease progression in Takayasu arteritis. Colour doppler ultrasonography may serve as a reliable and safe surrogate disease activity measure at follow up, as it avoids the radioactivity exposure and invasiveness of angiography.


2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Debashish Danda ◽  
Ripal Shah ◽  
Sathiyamoorthy Jothy ◽  
Shivraj Padiyar ◽  
Ramaswamy Subramanian ◽  
...  

2011 ◽  
Vol 139 (9-10) ◽  
pp. 572-578 ◽  
Author(s):  
Ivan Marjanovic ◽  
Milija Mijajlovic ◽  
Nadezda Covickovic-Sternic ◽  
Djordje Kontic ◽  
Paraskeva Hentova-Sencanic ◽  
...  

Introduction. An altered perfusion of the optic nerve head has been proposed as a pathogenic factor in glaucoma. Objective. The aim of this study was to evaluate the correlation between ocular pulse amplitude (OPA), measured by Dynamic contour tonometer (DCT) and colour Doppler imaging (CDI) of the arteric retro- bulbar vessels. Methods. Twenty patients older than 50 years were examined, and divided into two equal groups. The first group comprised of patients with normal tension glaucoma treated with topical antiglaucomatous therapy, and the second group included patients with ocular hypertension and glaucoma suspicious without any antiglaucomatous therapy. Ocular pulse amplitude (OPA) was measured with DCT. CDI was also performed. We measured haemodynamic parameters of the internal carotid artery (ICA), ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary arteries (PCA). Peak systolic (PSV), end- diastolic (EDV) velocities were measured, and resistance index (RI) and pulsatility index (PI) were calculated. Results Correlation with OPA showed indirect servitude in the RI of the ICA, RI and PI of the CRA, in the first group; and in the PSV and EDV of the ICA, in the RI and PI of the OA, EDV and RI of the CRA, and RI of the PCA, in the second group Conclusion. Increase of OPA was mostly followed by the increase of the parameters (PSV, EDV, RI, and PI) of the arteric retrobulbar vessels in the first group; in the second group, increase of OPA was in almost 50% of parameters followed by their decrease.


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