A technique for safe deep facial tissue dissection: Indocyanine green–assisted intraoperative real-time visualization of the vasa nervorum of facial nerve with a near-infrared camera

2019 ◽  
Vol 47 (11) ◽  
pp. 1819-1826 ◽  
Author(s):  
Jin Geun Kwon ◽  
Young Jun Choi ◽  
Sung Chan Kim ◽  
Joon Pio Hong ◽  
Woo Shik Jeong ◽  
...  
2019 ◽  
Vol 26 (4) ◽  
pp. 464-468 ◽  
Author(s):  
Pranav Mandovra ◽  
Vishaka Kalikar ◽  
Roy V. Patankar

Background. Intraoperative ureteral injury is rare, but a grave complication during laparoscopic surgery. Several methods for intraoperative localization of ureters are described with their own pitfalls. Intraoperative localization using near-infrared (NIR) fluorescence with indocyanine green (ICG) is an easier and assured method during laparoscopic pelvic surgeries. Method. From September 2017 to December 2017, patients undergoing laparoscopic pelvic surgeries were administered cystoscopic-guided intraureteral ICG immediately preoperatively with tip of a 6-Fr ureteral catheter. The fluorescence of ureters was visualized in the NIR mode of the camera system, localizing the ureters precisely and in real time. Results. This technique was used to visualize ureters in 30 surgeries. Median age of the patients was 46.7 years with median body mass index of 23.2 kg/m2. Mean duration between administration of dye and insertion of trocar was 10 minutes. Mean duration for insertion of cystoscopically guided intraureteral ICG was 7 minutes. Ureteral fluorescence was visualized in all cases with some variation in intensity of the brightness perceived depending on surrounding fat. Duration of the lengthiest surgery was 240 minutes, and fluorescence was appreciated till the end. There were no intraoperative or postoperative complications attributed to ICG administration. In 10 patients (33%), there was difficulty in identifying the ureters on conventional white light mode, in which ICG localization was extremely helpful. Conclusion. ICG-stained ureteral visualization under NIR light is a safe and feasible method that provides real-time ureteral demarcation. This easily replicable, sensitive, and specific method of ureteral visualization can make complex laparoscopic pelvic surgeries safer.


Author(s):  
Tamim Ahmed ◽  
Khandker Sadia Rahman ◽  
Sk Subrina Shawlin ◽  
Mohammad Hasan ◽  
Arnab Bhattacharjee ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jeffrey Dalli ◽  
Eamon Loughman ◽  
Niall Hardy ◽  
Anwesha Sarkar ◽  
Mohammad Faraz Khan ◽  
...  

AbstractAs indocyanine green (ICG) with near-infrared (NIR) endoscopy enhances real-time intraoperative tissue microperfusion appreciation, it may also dynamically reveal neoplasia distinctively from normal tissue especially with video software fluorescence analysis. Colorectal tumours of patients were imaged mucosally following ICG administration (0.25 mg/kg i.v.) using an endo-laparoscopic NIR system (PINPOINT Endoscopic Fluorescence System, Stryker) including immediate, continuous in situ visualization of rectal lesions transanally for up to 20 min. Spot and dynamic temporal fluorescence intensities (FI) were quantified using ImageJ (including videos at one frame/second, fps) and by a bespoke MATLAB® application that provided digitalized video tracking and signal logging at 30fps (Fluorescence Tracker App downloadable via MATLAB® file exchange). Statistical analysis of FI-time plots compared tumours (benign and malignant) against control during FI curve rise, peak and decline from apex. Early kinetic FI signal measurement delineated discriminative temporal signatures from tumours (n = 20, 9 cancers) offering rich data for analysis versus delayed spot measurement (n = 10 cancers). Malignant lesion dynamic curves peaked significantly later with a shallower gradient than normal tissue while benign lesions showed significantly greater and faster intensity drop from apex versus cancer. Automated tracker quantification efficiently expanded manual results and provided algorithmic KNN clustering. Photobleaching appeared clinically irrelevant. Analysis of a continuous stream of intraoperatively acquired early ICG fluorescence data can act as an in situ tumour-identifier with greater detail than later snapshot observation alone. Software quantification of such kinetic signatures may distinguish invasive from non-invasive neoplasia with potential for real-time in silico diagnosis.


2021 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Subramanyeshwar Rao Thammineedi

Abstract   Post esophagectomy anastomotic leakage and stricture are crucial factors in determining morbidity and mortality. Good vascularity of the gastric conduit is essential to avoid this complications. This prospective study assesses the utility of intraoperative indocyanine green (ICG) fluorescence imaging to determine gastric conduit vascularity in patients undergoing esophagectomy. Methods Thirteen consecutive patients who were undergoing esophagectomy for carcinoma middle, lower third esophagus or gastro-esophageal junction from August 2019 to September 2019, were included. Three patients underwent laparoscopic-assisted transhiatal esophagectomy, ten thoraco-laparoscopic assisted esophagectomy. Reconstruction was done by gastric pull up via posterior mediastinal route. Vascularity of gastric conduit was assessed by the near-infrared camera using ICG. Results On visual assessment of perfusion at the tip of gastric conduit, it was dusky in 11 patients, pink in two. Fuorescence imaging showed inadequate perfusion at the tip of conduit in 12 patients, needing revision. In one patient visual inspection showed adequate perfusion, but ICG disclosed poor vascularity requiring revision of the conduit’s tip. Resection of the devitalized portion of the proximal esophageal stump was needed in 5 patients both by visual and ICG assessment. The median time to appearance of blush from the time of injection of dye was 15 seconds (10 to 23 seconds). Conclusion Visual inspection of the gastric conduit vascularity can underestimate perfusion and hence can compromise resection of the devitalized part. ICG fluorescence imaging is more objective and promising means to ascertain the vascularity of gastric conduit during an esophagectomy. It could complement the visual inspection to decide the site of anastomosis.


2014 ◽  
Vol 2 (4) ◽  
pp. 180-183 ◽  
Author(s):  
Yasuyuki Mitani ◽  
Akio Kubota ◽  
Masaki Ueno ◽  
Katsunari Takifuji ◽  
Takashi Watanabe ◽  
...  

2021 ◽  
Vol 36 (1) ◽  
Author(s):  
K. Kaiser ◽  
M. Nayil ◽  
A. Ramzan ◽  
S. Sarbjit ◽  
W. Abrar ◽  
...  

Abstract Background Indocyanine green (ICG) is a near-infrared (NIR) fluorescent dye. After intravenous injection, it reaches the vessels of the brain within 30 s. A real-time visualization of the cerebral vasculature is possible. Results The infarction rate and the postoperative rebleed rate in the pre-ICG era group were higher than in the ICG era. Conclusion Intraoperative ICGVA is a safe and effective method to confirm the exclusion of the clipped aneurysm from the circulation. It also helps to assess the patency of the surrounding vessels.


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