Canine Cutaneous Spindle Cell Tumours with Features of Peripheral Nerve Sheath Tumours: A Histopathological and Immunohistochemical Study

2008 ◽  
Vol 139 (1) ◽  
pp. 16-23 ◽  
Author(s):  
L. Gaitero ◽  
S. Añor ◽  
D. Fondevila ◽  
M. Pumarola
Keyword(s):  
Peripheral Nerve ◽  
Spindle Cell ◽  
Immunohistochemical Study ◽  
Nerve Sheath ◽  
Spindle Cell Tumours

scholarly journals Growth-associated protein 43 in differentiating peripheral nerve sheath tumors from other non-neural spindle cell neoplasms

2013 ◽  
Vol 27 (2) ◽  
pp. 184-193 ◽  
Author(s):  
Wei-Shen Chen ◽  
Pei-Ling Chen ◽  
Dongsi Lu ◽  
Anne C Lind ◽  
Louis P Dehner
Keyword(s):  
Peripheral Nerve ◽  
Spindle Cell ◽  
Nerve Sheath Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath

Congenital Supratentorial and Infratentorial Peripheral Neurogenic Tumor: A Clinical, Ultrastructural, and Immunohistochemical Study

Neurosurgery ◽  
1986 ◽  
Vol 19 (3) ◽  
pp. 426-433 ◽  
Author(s):  
David S. Moss ◽  
Stephen J. Haines ◽  
Arnold S. Leonard ◽  
Louis P. Dehner
Keyword(s):  
Spindle Cell ◽  
Immunohistochemical Study ◽  
Operative Procedure ◽  
Cranial Nerves ◽  
Vascular Differentiation ◽  
Spindle Cell Neoplasm ◽  
Nerve Sheath ◽  
Neuroectodermal Tumors ◽  
The Central Nervous System ◽  
Supratentorial Mass

Abstract Congenital neoplasms of the central nervous system are extremely rare, although they have been well documented since the earliest reports from the mid-19th century. Medulloblastoma, other primitive neuroectodermal tumors, and various types of gliomas have comprised the majority of cases. This report describes a highly unusual infratentorial and supratentorial tumor presenting as a scalp mass in a neonate who experienced in utero distress. The supratentorial mass extended through a defect in the skull to the parietooccipital lobe, and the infratentorial aspect involved the 9th and 10th cranial nerves in the region of the cerebellopontine angle. A complex spindle cell neoplasm incorporating peripheral nerve sheath and vascular characteristics was further characterized by electron microscopy and immunohistochemistry. Based upon these studies, the tumor was interpreted as a congenital schwannoma with divergent vascular differentiation. The child has been tumor-free for approximately 2 years after the initial operative procedure.

A Rare Cause of Primary Hepatic Neoplasm: Malignant Peripheral Nerve Sheath Tumor in the Age of Modern Liver Surgery

2008 ◽  
Vol 74 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Douglas M. Iddings ◽  
Byron E. Wright ◽  
Anton Bilchik
Keyword(s):  
Peripheral Nerve ◽  
Biopsy Specimen ◽  
Spindle Cell ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Spindle Cells ◽  
Clinical Diagnoses ◽  
Impact On Treatment ◽  
Hepatic Neoplasm

Primary malignant peripheral nerve sheath tumor (MPNST) of the liver is rare. Histologic identification of spindle cells from a biopsy specimen and the potential clinical diagnoses are discussed. Potential metastatic and primary spindle cell lesions, as well as their impact on treatment decisions are considered. This was successfully treated with ablation assisted surgical resection and minimal blood loss.

Cutaneous Malignant Peripheral Nerve Sheath Tumour (Mpnst) of the Hand: A Review of Current Literature

1993 ◽  
Vol 18 (4) ◽  
pp. 478-481 ◽  
Author(s):  
M. S. E. COADY ◽  
S. POLACARZ ◽  
R. E. PAGE
Keyword(s):  
Peripheral Nerve ◽  
Upper Limb ◽  
Soft Tissues ◽  
Spindle Cell ◽  
Current Knowledge ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Tumour Extension ◽  
Therapeutic Problem ◽  
Peripheral Nerve Sheath Tumour

Malignant peripheral nerve sheath tumours (MPNST) are spindle cell sarcomas normally situated in the deep soft tissues. Cutaneous MPNST is an uncommon variant, usually occurring in the head and neck. When it arises in the upper limb this tumour may pose a considerable diagnostic and therapeutic problem. We present a case of cutaneous MPNST arising in the hand. Tumour extension was exclusively perineural along three major nerve trunks from an interdigital origin. Current knowledge of the clinical behaviour of cutaneous MPNST is reviewed.

Malignant Peripheral Nerve Sheath Tumor of Frontal Sinus: A Case Report, Literature Review, and Immunohistochemical Study

2017 ◽  
Vol 3 (1) ◽  
pp. 1-3
Author(s):  
Mojtaba Babaei Zarch ◽  
Mansour Moghimi ◽  
Mohammad Hossein Dadgarnia ◽  
Seyed Mojtaba Ghelmani ◽  
Mohammad Baghi Yazdi ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Peripheral Nerve ◽  
Frontal Sinus ◽  
Immunohistochemical Study ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Metastatic melanoma presenting as a malignant peripheral nerve sheath tumour

2021 ◽  
Vol 5 (1) ◽  
pp. 1-4
Author(s):  
David John Mackay Smith
Keyword(s):  
Peripheral Nerve ◽  
Metastatic Melanoma ◽  
Spindle Cell ◽  
Correct Diagnosis ◽  
Primary Cutaneous Melanoma ◽  
Tissue Mass ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Spindle Cell Proliferation ◽  
Peripheral Nerve Sheath Tumour

This is a report of a metastatic melanoma presenting clinically as a soft tissue mass and histologically being diagnosed as a malignant peripheral nerve sheath tumour. In this case the metastatic melanoma was preceded by a primary cutaneous melanoma in a similar anatomical region. Histologically the tumour was characterised by a malignant-appearing Spindle cell proliferation, arranged in fascicules. There was no evidence of connection to a nerve, co-existent neurofibroma or stigmata of neurofibromatosis. This presentation is only infrequently mentioned in the literature and heterogeneity can make clinical and histological diagnosis of metastatic melanoma problematic. It can easily be misinterpreted without effective clinico-histological correlation, making a good working relationship between Clinician and Histopathologist essential for correct diagnosis.

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