The relationship between low resting heart rate, systolic blood pressure and antisocial behavior in incarcerated males

2018 ◽  
Vol 55 ◽  
pp. 88-95 ◽  
Author(s):  
Christopher J. Koegl ◽  
David P. Farrington ◽  
Adrian Raine
2021 ◽  
Vol 10 (15) ◽  
pp. 3264
Author(s):  
Piotr Sobieraj ◽  
Maciej Siński ◽  
Jacek Lewandowski

The association between elevated resting heart rate (RHR) as a cardiovascular risk factor and lowering of systolic blood pressure (SBP) to currently recommended values remain unknown. Systolic Blood Pressure Intervention Trial (SPRINT) data obtained from the NHLBI were used to describe the relationship between RHR and SBP reduction to <120 mmHg compared to SBP reduction to <140 mmHg. The composite clinical endpoint (CE) was defined as myocardial infarction, acute coronary syndrome, decompensation of heart failure, stroke, or cardiovascular death. Increased RHR was associated with a higher CE risk compared with low RHR in both treatment arms. A more potent increase of risk for CE was observed in subjects who were allocated to the SBP < 120 mmHg treatment goal. A similar effect of intensive and standard blood pressure (BP) reduction (p for interaction, 0.826) was observed in subjects with RHR in the 5th quintile (hazard ratio, 0.78, with 95% confidence interval (CI), 0.55–1.11) and in other quintiles of baseline RHR (hazard ratio, 0.75, with 95% CI, 0.62–0.90). Lower in-trial than baseline RHR was associated with reduced CE risk (hazard ratio, 0.80, with 95% CI, 0.66–0.98). We concluded that elevated RHR remains an essential risk factor independent of SBP reduction.


2009 ◽  
Vol 36 (11) ◽  
pp. 1125-1140 ◽  
Author(s):  
Todd A. Armstrong ◽  
Shawn Keller ◽  
Travis W. Franklin ◽  
Scott N. Macmillan

Despite a large body of research demonstrating a clear and consistent relationship between resting heart rate and antisocial behavior, little is understood about the relative influence on antisocial behavior of resting heart rate and other constructs central to criminological theories. Here, the authors offer an initial effort to bridge this gap in the literature by testing the relationship between resting heart rate and a measure of antisocial behavior net of attachment to parents, self-control, peer delinquency, and potential physiological confounds. Results from ANOVA show that those with low resting heart rates have significantly higher rates of severe antisocial behavior and aggressive antisocial behavior net of physiological confounds. Results from multivariate regression models show that low resting heart rate has a statistically significant relationship with severe antisocial behavior and aggressive behavior in models controlling for attachment to parents, self-control, peer delinquency, and physiological confounds.


Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Steven J Mould ◽  
Elsayed Z Soliman ◽  
Yashashwi Pokharel ◽  
Elijah Beaty ◽  
Prashant Bhave ◽  
...  

Introduction: Elevated resting heart rate (RHR) has been shown to be associated with both all-cause and cardiovascular mortality. Prior studies have provided conflicting estimates of the strength of each association. To explore the relationship between RHR and competing mortality risks, we sought to compare the association between RHR and cardiovascular and non-cardiovascular mortality among participants in the Systolic Blood Pressure Intervention Trial (SPRINT). Methods: Eligible SPRINT participants had baseline RHR, longitudinal follow-up, and were not using beta blockers or non-dihydropyridine calcium channel blockers. Mortality was classified by a treatment-blinded adjudication committee as cardiovascular if secondary to coronary heart disease, stroke, sudden cardiac death, or congestive heart failure. Multivariable Cox proportional hazards models were used to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CI) for cardiovascular and non-cardiovascular mortality, separately, associated with a 10 beats per minute increase in RHR. Results: Among 5,571 eligible SPRINT participants (67.1 ± 9.4 years, 33.8% female, 63.8% white, mean RHR 70.4±11.8 beats per minute) over a median 3.8 years of follow-up, there were 56 cardiovascular deaths and 176 non-cardiovascular deaths. In models adjusted for age, sex, race, prior cardiovascular disease, smoking, systolic blood pressure, creatinine, total cholesterol, high-density lipoprotein cholesterol, and trial treatment assignment, higher RHR (per ten beat-per-minute increase) was associated with both cardiovascular (HR 1.17, 95% CI 1.02-1.35) and non-cardiovascular mortality (HR 1.27, 95% CI 1.13-1.43). Conclusions: Elevated RHR was associated with both cardiovascular and non-cardiovascular mortality, suggesting that RHR may serve as a marker of both global health rather and cardiovascular health. Higher RHR may reflect imbalance in autonomic tone and further studies are needed to explore the mechanisms of these associations.4


2018 ◽  
Vol 20 (6) ◽  
pp. 1021-1030 ◽  
Author(s):  
Michael Böhm ◽  
Victoria L. Cammann ◽  
Jelena R. Ghadri ◽  
Christian Ukena ◽  
Sebastiano Gili ◽  
...  

PEDIATRICS ◽  
1995 ◽  
Vol 96 (6) ◽  
pp. 1123-1125
Author(s):  
Bernard Gutin ◽  
Syed Islam ◽  
Frank Treiber ◽  
Clayton Smith ◽  
Tina Manos

Objective. One mechanism through which hyperinsulinemia is linked to hypertension is through its stimulation of sympathetic nervous activity. Thus, insulin concentration may be correlated with indices of sympathetic activity before it is associated with resting blood pressure. We tested this hypothesis by determining the relationship of insulin concentration and sympathetically mediated cardiovascular reactivity to exercise in children. Design. Survey. Setting. General community. Participants. Volunteer sample of 46 black and white boys and girls, 9 to 11 years of age. Interventions. None. Fasting insulin concentration was the main independent variable. Main outcome measures. Systolic blood pressure and heart rate during a standard submaximal bout of treadmill exercise, and systolic blood pressure at peak effort. Results. The hypothesis was tested by multiple regression analyses controlled for resting values. Insulin contributed significantly to the regression models for submaximal heart rate (P &lt; .001), submaximal systolic blood pressure (P = .001), and peak systolic blood pressure (P = .006). Conclusions. Fasting insulin concentration is associated with cardiovascular reactivity to exercise in young children. This supports the hypothesis that the relationship between hyperinsulinemia and hypertension is mediated by sympathetic nervous tone and that the process begins in childhood. Because percent body fat was positively associated with both insulin and cardiovascular reactivity to exercise, prevention of childhood obesity may be a valuable prophylactic measure for these health problems.


2010 ◽  
Vol 7 (6) ◽  
pp. 737-745 ◽  
Author(s):  
Anthony Musto ◽  
Kevin Jacobs ◽  
Mark Nash ◽  
Gianluca DelRossi ◽  
Arlette Perry

Background:Pedometer programs can increase physical activity in sedentary individuals, a population that is at risk for developing metabolic syndrome and each of its individual components. Although the popular 10,000 steps/day recommendation has shown to induce many favorable health benefits, it may be out of reach for sedentary individuals. This study observed the effects of incremental increases in steps/day on metabolic syndrome components in sedentary overweight women.Methods:This study was a longitudinal, quasiexperimental design. Participants were recruited from a 12-week work-site pedometer program and grouped as either ‘active’ or ‘control’ after the intervention based on their steps/day improvement. Self-reported physical activity, pedometer assessed physical activity, BMI, resting heart rate, waist circumference, blood pressure, triglycerides, HDLC, and fasting glucose were measured before and after the program.Results:The active group showed significant within-group improvements in waist circumference and fasting glucose. Significant group differences were observed in resting heart rate, BMI, and systolic blood pressure; however, the changes observed in systolic blood pressure were not independent of weight loss.Conclusions:Incremental increases in steps/day induced favorable changes in some MetS components suggesting that this approach is a viable starting point for sedentary individuals that may find it difficult to initially accumulate 10,000 steps/day.


1993 ◽  
Vol 76 (2) ◽  
pp. 701-702
Author(s):  
John E. Martin ◽  
Christi A. Patten ◽  
Colin A. Armstrong

In 18 normotensive adults (15 women, 3 men), higher levels of habitual physical activity were significantly associated with lower diastolic blood pressure, but not with systolic blood pressure or resting heart rate.


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