scholarly journals Comparison of serum neopterin levels in pulmonary tuberculosis patients with positive acid fast bacilli and inactive pulmonary tuberculosis

Author(s):  
Soedarsono Soedarsono ◽  
Parluhutan Dolli
Author(s):  
Atul Luhadia ◽  
Shanti K. Luhadia ◽  
Shubham Jain ◽  
Mohammad Hamza Hanfe ◽  
Divax Oza ◽  
...  

Background: Sputum smear negative pulmonary tuberculosis is a common problem faced by clinicians. Fiberoptic bronchoscopy may be very useful in diagnosing these cases which have no sputum or whose sputum smear is negative for acid fast bacilli. Objective of the current study was to assess the role of fiberoptic bronchoscopy in sputum smear negative under NTEP and radiologically suspected cases of pulmonary tuberculosis.Methods: Clinico-radiological suspected cases of pulmonary tuberculosis patients in whom two sputum smear for acid fast bacilli by Ziehl Neelsen stain under NTEP was negative were included in the study. Fiberoptic bronchoscopy was performed in all these patients and samples taken were sent for investigations.Results: Fiberoptic bronchoscopy was performed in 250 patients of suspected pulmonary tuberculosis whose sputum for AFB smear was negative. Cough was the most predominant symptom. Radiologically, right side disease was more common and upper zone was most commonly involved and infiltrates were common radiological finding. During bronchoscopy, congestion and hyperaemia (36%) and mucopurulent/mucoid secretions (32%) was seen in maximum number of cases. BAL was positive in 200 patients (80%), post bronchoscopy sputum was positive in 70 cases (28%) and biopsy was positive in 12 patients out of 16 performed biopsies (75%). The total TB positive cases after combining all the methods were 215 making the overall diagnostic yield of 86%.Conclusions: Fiberoptic bronchoscopy and post bronchoscopy sputum can be very useful for diagnosing sputum for AFB smear negative but clinico-radiological suspected cases of pulmonary tuberculosis patients.


Author(s):  
Kshitija Sanjeev Shinde

For comparative study known patients of pulmonary tuberculosis are selected. Which are diagnosed on the basis of x-ray chest, sputum-acid fast bacilli, erythrocyte sedimentation rate. And in the pulmonary tuberculosis patients observed the symptoms of rajayakshma. Other findings are observed as per age, sex, economic condition,occupation, habits, prakruti, agni, kostha, satwa, nidan panchak, updrava, doshadushti, dhatudushti, maladushti.


2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Nadya Magfira ◽  
Md Ikhsan Mokoagow ◽  
Ida Ayu Kshanti ◽  
Helda Nazar

Obesity is known as protective factors of pulmonary tuberculosis (PTB) innon-diabetes mellitus population. However, it’s effect on PTB in type 2diabetes mellitus (T2DM) patient is unclear. The study aims to determinethe association between obesity and PTB in patient with T2DM. A crosssectional study was held in in-patient, The Department of Internal Medicine, Fatmawati General Hospital from January 2015 to December 2017.This study includes patient with T2DM who had been diagnosed with PTBand age > 18 years old. In this study negative Acid-fast-bacilli (AFB)founding defined as patient’s sputum is negative by smear microscopy,while obesity define as body mass index > 24.9 kg/m2. From 363 PTBpatient with T2DM, 22.59% were obese. Results showed that prevalenceof negative AFB founding in PTB patients with T2DM was 81.82% and itwas solely associated with obesity (p:0.002, OR=6.36, 95%CI 1.9-21). Obesepatients were likely to have negative AFB founding. It suggested thatdiagnosing PTB in patient with T2DM and obese can’t be solely based onbacteriological confirmation


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