Associations of hyperglycemia and insulin resistance with biomarkers of endothelial dysfunction in Hispanic/Latino youths: Results from the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth)

Abstract Background. Maintaining a bond with one’s family as well coping with stress while acculturating to the US may protect Hispanic/Latino youth from increased sugar-sweetened beverages (SSB) consumption, which heightens the risk for overweight and obesity. This study aims to examine associations between acculturative stress, family functioning, and SSB consumption by acculturation status among U.S. Hispanic/Latino youth.Methods. With cross-sectional data on 1,465 youth 8-16y (49.6% females) participating in the Hispanic Community Children's Health Study/Study of Latino Youth, we classified youths into four acculturation groups – assimilated, integrated, marginalized/separated, and unclassified. SSB consumption was assessed through two 24-hour diet recalls and defined as intake frequency of soda, fruit juice, sweetened soft and fruit drinks. Multi-group path regression models were used to test associations of Hispanic/Latino youth’ acculturative stress and family functioning with SSB consumption, as well as the moderating role of acculturation status.Results. When controlling for age, sex, and study site, acculturative stress (β = -0.13, p = 0.01) was inversely associated with SSB, and poor family functioning (β = 0.11, p = 0.07) was only marginally associated with SSB consumption among youth classified as assimilated but not among youth classified as integrated, marginalized/separated, or unclassified. Conclusions. A socio-ecological perspective that incorporates the role of key acculturation-related factors across multiple levels may aid efforts to identify mechanisms that influence the relationship between acculturation status and diet among Hispanic/Latino youth and their families.

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Associations between family functioning, acculturative stress, and sugar-sweetened beverage consumption in the Hispanic Community Children's Health Study/Study of Latino Youth

10.21203/rs.3.rs-21907/v1 ◽

2020 ◽

Author(s):

Roger Figueroa ◽

Carmen R Isasi ◽

Krista M Perreira ◽

Amanda McClain ◽

Linda C Gallo ◽

...

Keyword(s):

Family Functioning ◽

Acculturative Stress ◽

Latino Youth ◽

Children's Health ◽

Children’S Health ◽

Health Study ◽

Related Factors ◽

Hispanic Community ◽

Children's Health Study

Abstract Background. Maintaining a bond with one’s family as well coping with stress while acculturating to the US may protect Hispanic/Latino youth from increased sugar-sweetened beverages (SSB) consumption. This study aims to examine associations between acculturative stress, family functioning, and SSB consumption by acculturation status among U.S. Hispanic/Latino youth. Methods. With data on 1,465 youth 8-16y (49.6% females) participating in the Hispanic Community Children's Health Study/Study of Latino Youth, we classified youths into four acculturation groups – assimilated, integrated, marginalized/separated, and unclassified. SSB consumption was assessed through two 24-hour diet recalls and defined as intake frequency of soda, fruit juice, sweetened soft and fruit drinks. Multi-group path regression models were used to test associations of Hispanic/Latino youth’ acculturative stress and family functioning with SSB consumption, as well as the moderating role of acculturation status. Results. When controlling for age, sex, and study site, acculturative stress (β = -0.13, p = 0.01) was inversely associated with SSB, and poor family functioning (β = 0.11, p = 0.07) was only marginally associated with SSB consumption among youth classified as assimilated but not among youth classified as integrated, marginalized/separated, or unclassified. Conclusions. A socio-ecological perspective that incorporates the role of key acculturation-related factors across multiple levels may aid efforts to identify mechanisms that influence the relationship between acculturation status and diet among Hispanic/Latino youth and their families.

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Targeting family functioning, acculturative stress, and sugar-sweetened beverage consumption for obesity prevention: Findings from the Hispanic Community Children's Health Study/Study of Latino Youth

10.21203/rs.3.rs-21907/v3 ◽

2020 ◽

Author(s):

Roger Figueroa ◽

Carmen R Isasi ◽

Krista M Perreira ◽

Amanda McClain ◽

Linda C Gallo ◽

...

Keyword(s):

Family Functioning ◽

Acculturative Stress ◽

Latino Youth ◽

Overweight And Obesity ◽

Children's Health ◽

Children’S Health ◽

Health Study ◽

Hispanic Community ◽

Children's Health Study

Abstract Background. Maintaining a bond with one’s family as well coping with stress while acculturating to the US may protect Hispanic/Latino youth from increased sugar-sweetened beverages (SSB) consumption, which heightens the risk for overweight and obesity. This study aims to examine associations between acculturative stress, family functioning, and SSB consumption by acculturation status among U.S. Hispanic/Latino youth.Methods. With cross-sectional data on 1,465 youth 8-16y (49.6% females) participating in the Hispanic Community Children's Health Study/Study of Latino Youth, we classified youths into four acculturation groups – assimilated, integrated, marginalized/separated, and unclassified. SSB consumption was assessed through two 24-hour diet recalls and defined as intake frequency of soda, fruit juice, sweetened soft and fruit drinks. Multi-group path regression models were used to test associations of Hispanic/Latino youth’ acculturative stress and family functioning with SSB consumption, as well as the moderating role of acculturation status.Results. When controlling for age, sex, and study site, acculturative stress (β = -0.13, p = 0.01) was inversely associated with SSB, and poor family functioning (β = 0.11, p = 0.07) was only marginally associated with SSB consumption among youth classified as assimilated but not among youth classified as integrated, marginalized/separated, or unclassified. Conclusions. A socio-ecological perspective that incorporates the role of key acculturation-related factors across multiple levels may aid efforts to identify mechanisms that influence the relationship between acculturation status and diet among Hispanic/Latino youth and their families.

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Diet quality comparisons in Hispanic/Latino siblings: Results from the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth)

Appetite ◽

10.1016/j.appet.2021.105809 ◽

2021 ◽

pp. 105809

Author(s):

Madison N. LeCroy ◽

Yasmin Mossavar-Rahmani ◽

Xiaonan Xue ◽

Tao Wang ◽

Linda C. Gallo ◽

...

Keyword(s):

Diet Quality ◽

Latino Youth ◽

Children's Health ◽

Children’S Health ◽

Health Study ◽

Hispanic Community ◽

Children's Health Study

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Abstract P027: Liver Enzymes and Insulin Resistance and Glycemia in Hispanic/Latino Youth: Results From the Hispanic Community Children’s Health Study/Study of Latino Youth (SOL Youth)

Circulation ◽

10.1161/circ.133.suppl_1.p027 ◽

2016 ◽

Vol 133 (suppl_1) ◽

Author(s):

Christina M Parrinello ◽

Bryan J Rudolph ◽

Mariana Lazo ◽

Linda C Gallo ◽

Bharat Thyagarajan ◽

...

Keyword(s):

Insulin Resistance ◽

Endothelial Dysfunction ◽

Liver Enzyme ◽

Liver Enzymes ◽

Latino Youth ◽

Children's Health ◽

Health Study ◽

Obese Children ◽

Hispanic Community ◽

Elevated Liver Enzymes

Background: Associations of insulin resistance and glycemia with liver enzymes have not been well studied in a young, heterogeneous Hispanic/Latino population. We aimed to assess these associations, and to examine the role of endothelial dysfunction as a potential mediator. Methods: We examined 1,275 participants aged 8-16 years from the Hispanic Community Children’s Health Study/Study of Latino Youth (SOL Youth) (2012-14). We examined the distribution of liver enzymes (alanine transaminase [ALT], aspartate transaminase [AST], and gamma-glutamyl transpeptidase [GGT]), the pediatric nonalcoholic fatty liver disease (NAFLD) fibrosis index (PNFI), glycemic markers (fasting glucose and hemoglobin A1c [HbA1c]), and insulin resistance (HOMA-IR) by age, sex, and body mass index (BMI). We assessed the adjusted cross-sectional associations of insulin resistance and hyperglycemia (as continuous variables) with elevated liver enzymes and PNFI (as binary variables) using Poisson regression to obtain prevalence ratios (PRs). Results: Boys were more likely than girls to have elevated liver enzyme levels (15 vs 10%, 5 vs 2%, 26 vs 16%, and 12 vs 11% had elevated ALT, AST, GGT, and PNFI, respectively) and hyperglycemia (15 vs 6% and 9 vs 8% had elevated glucose and HbA1c), but less likely to be insulin resistant (47 vs 59%). Obese children (BMI≥95 th percentile) were more likely to have higher liver enzyme levels, hyperglycemia, and insulin resistance than non-obese children. Only HOMA-IR was associated with elevated liver enzymes and PNFI in multivariable models ( Figure ). After additional adjustment for PAI-1, and e-selectin (markers of endothelial dysfunction), only the associations of HOMA-IR with GGT and PNFI remained statistically significant (PRs and 95% CIs: 1.43 [1.03, 1.98] and 1.85 [1.33, 2.56], respectively). Conclusions: Among a large sample of Hispanic/Latino youths, insulin resistance was associated with NAFLD. It is possible that these associations are partially mediated by endothelial dysfunction.

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