scholarly journals Periapical granuloma with actinomycosis

2021 ◽  
Author(s):  
Huai-Kuan Huang ◽  
Ming-Jay Hwang ◽  
Chun-Pin Chiang ◽  
Ling-Huey Chueh
Keyword(s):  
Periapical Granuloma

scholarly journals Immunohistochemical analysis of ADAMTS-1, versican and pEGFR expressions in periapical granuloma and radicular cyst

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nádia Marielly Gomes Batista ◽  
Antonia Taiane Lopes de Moraes ◽  
Karolyny Martins Balbinot ◽  
Osvaldo Rodrigues de Souza Neto ◽  
Juliana Melo da Silva Brandão ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Immunohistochemical Analysis ◽  
Dental Follicle ◽  
Radicular Cyst ◽  
Periapical Lesions ◽  
Periapical Granuloma ◽  
Inflammatory Processes

Abstract Background ADAMTS expression can be associated with several inflammatory processes, and has been correlated with tumorigenesis of some neoplasms, but its participation in the development of periapical lesions has not been investigated. Therefore, our objective was to verify the expression of ADAMTS-1, versican and pEGFR in Periapical Granuloma (PG) and in the Radicular Cyst (RC) since they are the most common lesions of the periapex. Methods 25 samples of RC and 10 of PG were used. As a control, 10 samples of inflammatory fibrous hyperplasia (IFH) and 10 of dental follicle (DF) were used. The expression of these proteins was investigated using immunohistochemistry. Results In the epithelium of RC, IFH and DF, the expression of ADAMTS-1 was greater in DF than in RC (p < .001). Versicano showed greater expression in IFH than in RC, DF than in RC (p < .001). pEGFR showed greater expression in IFH and RC than in DF (p < .01 and p < .05, respectively). In connective tissue, ADAMTS-1 expression was greater in PG and RC than in IFH and DF (p < .001). Versicano showed greater expression in PG, RC and IFH compared to DF (p < .001). In pEGFR there was a higher expression in PG when compared to RC, IFH and DF (p < .001). Greater immunostaining occurred in the RC than in the DF (p < .001). Conclusions Our results suggest that the studied proteins may participate in the pathogenesis of PG and RC, through the interaction of these proteins, in the remodeling of the ECM (versican) by ADAMTS-1, producing bioactive fragments, which could activate EGFR, contributing to the formation, growth and maintenance of injuries.

scholarly journals Analysis of the presence and location of mast cells in periapical cysts and periapical granulomas

2016 ◽  
Vol 64 (4) ◽  
pp. 376-381 ◽  
Author(s):  
Emerson Filipe de Carvalho NOGUEIRA ◽  
Elder Gyress Feitosa FARIAS ◽  
Luciano Barreto SILVA ◽  
Alexandrino Pereira dos SANTOS NETO ◽  
Emanuel Sávio de Souza ANDRADE ◽  
...  
Keyword(s):  
Mast Cells ◽  
Granulation Tissue ◽  
Blue Staining ◽  
Double Blind Study ◽  
Double Blind ◽  
Cross Sectional ◽  
Periapical Granuloma ◽  
Staining Methods ◽  
Periapical Cyst ◽  
Quantitative Descriptive

ABSTRACT Objective: The aim of the present study was to locate mast cells in chronic periapical lesions (granulomas and cysts) by using histochemical techniques and toluidine blue staining. Methods: A quantitative, descriptive, cross-sectional and retrospective research was performed. The sample was obtained from histopathological reports in the archives of the laboratory of surgical pathology of the University of Pernambuco between November 2014 and May 2015. Results: Sixteen cases of granuloma and 21 cases of periapical cysts were selected. The stained slides were analyzed by two examiners at different times, in a double-blind study. Mast cells were found in 13 (61.9%) of the periapical cyst cases, located in the capsule of the lesion. In the periapical granuloma cases, mast cells were found in eight cases (50%), located in the granulation tissue. Conclusion: Mast cells were detected in both cysts and periapical granuloma, located in the capsule and granulation tissue, respectively. Mast cells were more prevalent in periapical cysts than in periapical granuloma.

scholarly journals Comparative evaluation to determine the efficacy of conventional radiography, digital radiography and ultrasound imaging in the diagnosis of periapical lesions

2021 ◽  
Vol 1 (3) ◽  
Author(s):  
Rajesh Gupta ◽  
Preety Gupta ◽  
Shivani Gupta, ◽  
Sumit Garg
Keyword(s):  
Ultrasound Imaging ◽  
Digital Radiography ◽  
Histopathological Examination ◽  
Conventional Radiography ◽  
Test Results ◽  
Periapical Lesions ◽  
Periapical Granuloma ◽  
Mandibular Teeth ◽  
Wallis Anova ◽  
Histopathological Investigation

In recent time several imaging modalities have been implicated for diagnosing periapical lesion. The present study is carried out to determine and compare the nature and extent of periapical lesions using conventional radiography, digital radiography and ultrasound imaging and to confirm the diagnosis with histopathological examination. Thirty patients aged between 15 and 45 years with well-defined periapical radiolucency associated with anterior maxillary or mandibular teeth requiring endodontic surgery or extraction were selected. The pre-operative intraoral periapical radiographs and digital images and were diagnosed by three observers. Ultrasound examination was performed and the images were assessed by an ultrasonographer. The periapical tissues were obtained to enable histopathological investigation. The data was statistically analysed using the kappa procedure, Kruskal Wallis Anova & Mann-Whitney U test. Results showed that the percentage accuracy of diagnosing periapical lesions using conventional radiography, digital radiography and ultrasound was – 86.67%, 93.33% & 93.33% respectively. Thus, we conclude that ultrasound helps in distinguishing between periapical granuloma and cyst which is of importance in predicting the treatment outcome. So, ultrasound can be used as an adjunct to conventional or digital radiography in diagnosing periapical lesions.

RANKL in human periapical granuloma: possible involvement in periapical bone destruction

Oral Diseases ◽  
2006 ◽  
Vol 12 (3) ◽  
pp. 283-289 ◽  
Author(s):  
R Vernal ◽  
A Dezerega ◽  
N Dutzan ◽  
A Chaparro ◽  
R Leon ◽  
...  
Keyword(s):  
Bone Destruction ◽  
Periapical Granuloma

Expression and immunohistochemical localization of leptin receptor in human periapical granuloma

2014 ◽  
Vol 48 (6) ◽  
pp. 611-618 ◽  
Author(s):  
J. Martín-González ◽  
A. Carmona-Fernández ◽  
A. Pérez-Pérez ◽  
F. Sánchez-Jiménez ◽  
V. Sánchez-Margalet ◽  
...  
Keyword(s):  
Leptin Receptor ◽  
Immunohistochemical Localization ◽  
Periapical Granuloma

scholarly journals Cirurgia do periápice para remoção de lesões granulomatosas: relato de caso

2020 ◽  
Vol 61 (2) ◽  
pp. 129-135
Author(s):  
Sidinéia Feitoza De Jesus ◽  
Yasmim Santos Meneses ◽  
Rafaela Cardoso De-Sá ◽  
Vanessa Valente Elias ◽  
Marcio Santos De Carvalho ◽  
...  
Keyword(s):  
Inflammatory Infiltrate ◽  
Inflammatory Cells ◽  
Bovine Bone ◽  
Pulp Tissue ◽  
Root Canals ◽  
Granulomatous Lesions ◽  
Periapical Granuloma ◽  
History Of ◽  
Granulomatous Tissue ◽  
Periapical Inflammation

Periapical granuloma is a histological term that refers to the formation of a mass of granulomatous tissue around the apex of a tooth resulting from inflammation and necrosis of the pulp tissue. It consists of an infiltrate of inflammatory cells such as macrophages, plasmocytes and lymphocytes, as well as fibroblasts, collagen fibers and capillaries. Periapical surgery is an alternative for preserving the tooth in the oral cavity in cases where periapical inflammation is persistent even after treatment of root canals. The objective of this study was to report a clinical case in which the surgical technique was used to remove granulomatous lesions from a patient, female, with a history of recurrent periapical abscess without painful symptomatology in the region of the anterior 11,12 and 13 teeth. The histopathological exam demonstrated the presence of a granulomatous tissue with intense inflammatory infiltrate mixed, permeated with lymphocytes and high number of plasmocytes, confirming the diagnosis of periapical granuloma. The treatment was considered successful since the patient remained asymptomatic and there was incorporation of the inorganic bovine bone graft and initiation of bone neoformation in the periapical region.

scholarly journals Using Periapical Radiography to Differentiate Periapical Granuloma and Radicular Cysts

2016 ◽  
Vol 8 (2) ◽  
pp. 7-7
Author(s):  
Farrokh Farhadi ◽  
Seyed Sina Mirinezhad ◽  
Ali Zarandi
Keyword(s):  
Periapical Granuloma ◽  
Periapical Radiography

scholarly journals Periapical granuloma and collagenase.

Ensho ◽  
1988 ◽  
Vol 8 (4) ◽  
pp. 321-326
Author(s):  
Taro Hayakawa ◽  
Jun-ichi Kishi ◽  
Kyoko Yamashita ◽  
Yasushi Kawamura ◽  
Masahiko Fukaya ◽  
...  
Keyword(s):  
Periapical Granuloma
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