Preparation of uniform magnetic iron oxide nanoparticles by co-precipitation in a helical module microchannel reactor

Magnetic iron oxide nanoparticles are promising material for various biological applications. In the recent decades, magnetic iron oxide nanoparticles (MNPs) have great attention in biomedical applications such as drug delivery, magnetic resonance imaging (MRI) and magnetic fluid hyperthermia (MFH). This review focuses on the colloidal stability and monodispersity properties of MNPs, which pay more attention toward biomedical applications. The simplest and the most promising method for the synthesis of MNPs is co-precipitation. The biocompatible MNPs are more interested in MRI application. This review also apportions synthesis, characterization and applications of MNP in biological and biomedical as theranostics and imaging.

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Preparation and Properties of Magnetic Iron Oxide Nanoparticles for Biomedical Applications: A Brief Review

Journal of Advanced Research in Materials Science ◽

10.37934/arms.75.1.1018 ◽

2020 ◽

Vol 75 (1) ◽

pp. 10-18

Author(s):

Mostafa Yusefi ◽

Kamyar Shameli ◽

Ahmad Faris Jumaat

Keyword(s):

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Biomedical Applications ◽

Vital Role ◽

Oxide Nanoparticles ◽

Magnetic Iron Oxide Nanoparticles ◽

Magnetic Iron Oxide ◽

Research Areas ◽

Co Precipitation ◽

Multifunctional Properties

Magnetic Iron oxide in nanostructure form with multifunctional properties may play a vital role in myriad biomedical applications. Iron oxide nanoparticles (IONPs) are fabricated via various methods, including thermal decomposition, co-precipitation, polyol, bio-mineralization, and green synthesis processes. Therefore, different researchers produced IONPs via various techniques to show better water permeability, antioxidant activity, biocompatibility, biodegradability, and lower or no toxicity, as advantages compared to commercial magnetic agents used in innovative applications for modern societies. This review explains various fabrication methods of IONPs and their multifunctional properties. Overall, the new advanced approaches, issues and main challenges, surface modification and modern applications of IONPs are considered. Lastly, some future developments and the views in these research areas are also discussed.

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Study of Biological Activities of Magnetic Iron Oxide Nanoparticles Prepared by Co-Precipitation Method

Journal of Applied Sciences and Nanotechnology ◽

10.53293/jasn.2021.11635 ◽

2021 ◽

Vol 1 (2) ◽

pp. 37-48

Author(s):

Rania Huseen ◽

Ali Taha ◽

Oday Abdulhusein

Keyword(s):

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Biological Activities ◽

Precipitation Method ◽

Oxide Nanoparticles ◽

Magnetic Iron Oxide Nanoparticles ◽

Magnetic Iron Oxide ◽

Co Precipitation

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Investigation of Magnetic Iron Oxide Nanoparticle Properties with Co-Precipitation Methods under Different Reaction Conditions

Nanoscience &Nanotechnology-Asia ◽

10.2174/2210681210666200117145606 ◽

2020 ◽

Vol 10 ◽

Author(s):

Sema Salgın ◽

Uğur Salgın ◽

Nagihan Soyer

Keyword(s):

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Morphological Structure ◽

Precipitation Method ◽

Iron Oxide Nanoparticle ◽

Hydrodynamic Diameter ◽

Oxide Nanoparticles ◽

Magnetic Iron Oxide Nanoparticles ◽

Magnetic Iron Oxide ◽

Co Precipitation

: In this study, magnetic iron oxide nanoparticles were synthesized by cost effective and an easy co-precipitation method. The effects of reaction parameters such as the mole ratio of Fe2+/Fe3+ (1/1, 1/2 and 1/3) and the base type (NaOH and NH4OH) on the average hydrodynamic diameter, zeta potential, chemical and morphological structure and saturation magnetization values of magnetic iron oxide nanoparticles were systematically investigated. Magnetic iron oxide nanoparticles synthesized at the mole ratio of 1/2 using NH4OH base gave better results in terms of particle size and particle shape, magnetization value. In order to prevent the formation of different phases in the co-precipitation method, an alternative approach was developed and the reaction was performed using inert supercritical CO2 atmosphere.

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