The hydro-ethanolic extract of Acacia seyal (Mimosaceae) stem barks induced death in an ER-negative breast cancer cell line by the intrinsic pathway of apoptosis and inhibited cell migration

2018 ◽  
Vol 223 ◽  
pp. 41-50 ◽  
Author(s):  
Stephane Zingue ◽  
Thomas Michel ◽  
Julia Cisilotto ◽  
Alain Brice Tueche ◽  
Derek Tantoh Ndinteh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Migration ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Ethanolic Extract ◽  
Intrinsic Pathway ◽  
Acacia Seyal

scholarly journals Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line

2016 ◽  
Vol 49 (1) ◽  
Author(s):  
Kurt Buchegger ◽  
Carmen Ili ◽  
Ismael Riquelme ◽  
Pablo Letelier ◽  
Alejandro H. Corvalán ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Migration ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Migration And Invasion ◽  
Cell Migration And Invasion

scholarly journals Curcumin Analog Pentagamaboronon-0-Sorbitol Inhibits Cell Migration Activity of Triple Negative Breast Cancer Cell Line

2018 ◽  
Vol 9 (3) ◽  
pp. 126
Author(s):  
Ratna Dwi Ramadani ◽  
Rohmad Yudi Utomo ◽  
Adam Hermawan ◽  
Edy Meiyanto
Keyword(s):  
Breast Cancer ◽  
Cell Migration ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cell Line ◽  
Triple Negative ◽  
Cancer Cell Line ◽  
Dependent Manner

Mortality in cancer is primarily due to failure of metastasis prevention. One strategy to target the cancerous cell is Boron Neutron Captured Therapy which showed high affinity toward cancer cells and reported to have anti-proliferative as well as antimetastatic activities. Cancer Chemoprevention Research Center Faculty of Pharmacy Universitas Gadjah Mada, has developed boron-containing substance namely pentagamaboronon-0 (PGB-0) which is known to exhibit anticancer activity towards breast cancer cell. The purposes of this research are focused to explore the anti-migratory activities of PGB-0-So against triple negative breast cancer cell. The MTT cytotoxicity assay of PGB-0-So against 4T1 breast cancer cell line were found to exert potential effect in dose-dependent manner with IC50 values of 39 μM. The study of cell migration inhibition using in vitro wound healing assays and gelatin zymography on highly metastasis breast cancer cell line 4T1, following the treatment of sub IC50 doses of PGB-0-So complex slightly inhibited cell migration through the inhibition of matrix metalloproteinase-9 expression. These findings suggest that PGB-0-So is potential as an anticancer agent.Keywords : curcumin analogue, PGB-0-So, 4T1 Cells, migration, MMP-9 

scholarly journals SCD1 activity promotes cell migration via a PLD-mTOR pathway in the MDA-MB-231 triple-negative breast cancer cell line

Breast Cancer ◽  
2020 ◽  
Vol 27 (4) ◽  
pp. 594-606 ◽  
Author(s):  
Marine Lingrand ◽  
Simon Lalonde ◽  
Antoine Jutras-Carignan ◽  
Karl-F. Bergeron ◽  
Eric Rassart ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Migration ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cell Line ◽  
Triple Negative ◽  
Cancer Cell Line ◽  
Mtor Pathway

scholarly journals Activation of c-Src/HER1/STAT5b and HER1/ERK1/2 Signaling Pathways and Cell Migration by Hexachlorobenzene in MDA-MB-231 Human Breast Cancer Cell Line

2010 ◽  
Vol 120 (2) ◽  
pp. 284-296 ◽  
Author(s):  
Carolina A. Pontillo ◽  
María A. García ◽  
Delfina Peña ◽  
Claudia Cocca ◽  
Florencia Chiappini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Migration ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Human Breast Cancer ◽  
Cancer Cell Line ◽  
Human Breast Cancer Cell ◽  
Human Breast
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