scholarly journals Clinical characteristics of influenza virus-induced lower respiratory infection during the 2015 to 2016 season

2018 ◽  
Vol 24 (6) ◽  
pp. 407-413 ◽  
Author(s):  
Kazuhiro Uda ◽  
Kensuke Shoji ◽  
Chitose Koyama-Wakai ◽  
Munehiro Furuichi ◽  
Noriyasu Iwase ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Respiratory Infection ◽  
Clinical Characteristics ◽  
Lower Respiratory Infection

scholarly journals Title: Clinical Manifestations and Outcome of Viral Acute Lower Respiratory Infection in Hospitalised Children in Myanmar 

2021 ◽  
Author(s):  
Kazuhiro Kamata ◽  
Khin Nyo Thein ◽  
Lasham Di Ja ◽  
Nay Chi Win ◽  
Su Mon Kyaw Win ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Respiratory Infection ◽  
Clinical Manifestations ◽  
Morbidity And Mortality ◽  
World Health ◽  
Nasopharyngeal Swab ◽  
Acute Lower Respiratory Infection ◽  
High Morbidity ◽  
Lower Respiratory Infection ◽  
Syncytial Virus

Abstract Background Acute lower respiratory infection (ALRI) remains the leading cause of death in children worldwide, and viruses have been the major causative factors of ALRI after the introduction of bacterial conjugate vaccines. In Myanmar, ALRI is associated with high morbidity and mortality in children. However, detailed information on ALRI is currently lacking. Methods We conducted a prospective study to investigate the viral aetiologies, clinical manifestations, and outcomes of ALRI in hospitalised children at the Yankin Children Hospital, Yangon, Myanmar from May 2017 to April 2019. The World Health Organization’s definitions of ALRI and severe ALRI were used with minor modifications. For the patients with suspected viral ALRI, a nasopharyngeal swab was obtained, and rapid tests for influenza and respiratory syncytial virus (RSV) were performed, followed by real-time PCR for the 16 respiratory viruses causing ALRI. Clinical information was extracted from the medical records. Results Among the 5463 patients admitted with a diagnosis of ALRI, 570 (10.4%) were randomly enrolled in the study. The median age of the patients was 8 months (interquartile range, 4–15 months). The most common symptoms were cough (93%) and difficulty of breathing (73%), while the most common signs were tachypnoea (78%) and chest indrawing (67%). Sixteen potentially causative viruses were detected in 502 (88%) patients, with RSV B (36%) and rhinovirus (28%) being the most commonly detected. Multiple viruses were detected simultaneously in 221 patients (37%). Severe ALRI was diagnosed in 107 patients (19%). The mortality rate was 5%; influenza virus A (29%) and RSV B (21%) were commonly detected in such cases. Conclusions Viral ALRI in children has significant morbidity and mortality rates in Myanmar. RSV and rhinovirus were the most commonly detected, while influenza virus and RSV were the most common causes of mortality.

Aflatoxin and outcome from acute lower respiratory infection in children in The Philippines

1995 ◽  
Vol 15 (3) ◽  
pp. 209-216 ◽  
Author(s):  
D. W. Denning ◽  
S. C. Quiepo ◽  
D. G. Altman ◽  
K. Makarananda ◽  
G. E. Neal ◽  
...  
Keyword(s):  
Respiratory Infection ◽  
The Philippines ◽  
Acute Lower Respiratory Infection ◽  
Lower Respiratory Infection

scholarly journals SARS-CoV-2 and influenza virus coinfection among patients with severe acute respiratory infection during the first wave of COVID-19 pandemic in Bangladesh: a hospital-based descriptive study

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e053768
Author(s):  
Zubair Akhtar ◽  
Md Ariful Islam ◽  
Mohammad Abdul Aleem ◽  
Syeda Mah-E-Muneer ◽  
M Kaousar Ahmmed ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Hospital Mortality ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Descriptive Study ◽  
Tertiary Level ◽  
Future Studies ◽  
Severe Acute Respiratory Infection ◽  
Hospital Deaths ◽  
Secondary Outcomes

ObjectiveTo estimate the proportion of SARS-CoV-2 and influenza virus coinfection among severe acute respiratory infection (SARI) cases-patients during the first wave of COVID-19 pandemic in Bangladesh.DesignDescriptive study.SettingNine tertiary level hospitals across Bangladesh.ParticipantsPatients admitted as SARI (defined as cases with subjective or measured fever of ≥38 C° and cough with onset within the last 10 days and requiring hospital admission) case-patients.Primary and secondary outcomesProportion of SARS-CoV-2 and influenza virus coinfection and proportion of mortality among SARI case-patients.ResultsWe enrolled 1986 SARI case-patients with a median age: 28 years (IQR: 1.2–53 years), and 67.6% were male. Among them, 285 (14.3%) were infected with SARS-CoV-2; 175 (8.8%) were infected with the influenza virus, and five (0.3%) were coinfected with both viruses. There was a non-appearance of influenza during the usual peak season (May to July) in Bangladesh. SARS-CoV-2 infection was significantly more associated with diabetes (14.0% vs 5.9%, p<0.001) and hypertension (26.7% vs 11.5%, p<0.001). But influenza among SARI case-patients was significantly less associated with diabetes (4.0% vs 7.4%, p=0.047) and hypertension (5.7% vs 14.4%, p=0.001). The proportion of in-hospital deaths among SARS-CoV-2 infected SARI case-patients were higher (10.9% (n=31) vs 4.4% (n=75), p<0.001) than those without SARS-CoV-2 infection; the proportion of postdischarge deaths within 30 days was also higher (9.1% (n=25) vs 4.6% (n=74), p=0.001) among SARS-CoV-2 infected SARI case-patients than those without infection. No in-hospital mortality or postdischarge mortality was registered among the five coinfected SARI case-patients.ConclusionsOur findings suggest that coinfection with SARS-CoV-2 and influenza virus was not very common and had less disease severity considering mortality in Bangladesh. There was no circulating influenza virus during the influenza peak season during the COVID-19 pandemic in 2020. Future studies are warranted for further exploration.

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