EBNA1 antigen-specific CD8+ T cells in cerebrospinal fluid of patients with multiple sclerosis

2016 ◽  
Vol 294 ◽  
pp. 14-17 ◽  
Author(s):  
Hebun Erdur ◽  
Veronika Scholz ◽  
Mathias Streitz ◽  
Markus Hammer ◽  
Christian Meisel ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Cd8 T Cells

scholarly journals Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

2004 ◽  
Vol 101 (8) ◽  
pp. 2428-2433 ◽  
Author(s):  
C. Skulina ◽  
S. Schmidt ◽  
K. Dornmair ◽  
H. Babbe ◽  
A. Roers ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Cd8 T Cells

Quantification of EBNA-1-Specific CD8+ T-Cells in Cerebrospinal Fluid and Peripheral Blood of Patients with Multiple Sclerosis (P02.076)

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. P02.076-P02.076
Author(s):  
H. Erdur ◽  
C. Meisel ◽  
C. Schonemann ◽  
K.-P. Wandinger ◽  
B. Rosche
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Cd8 T Cells ◽  
Peripheral Blood

scholarly journals Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients

Brain ◽  
2002 ◽  
Vol 125 (3) ◽  
pp. 538-550 ◽  
Author(s):  
M. Jacobsen ◽  
S. Cepok ◽  
E. Quak ◽  
M. Happel ◽  
R. Gaber ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Cd8 T Cells ◽  
Memory Cd8 T Cells ◽  
Multiple Sclerosis Patients ◽  
Oligoclonal Expansion

Selective suppression of chemokine receptor CXCR3 expression by interferon-b1a in multiple sclerosis

2002 ◽  
Vol 8 (2) ◽  
pp. 104-107 ◽  
Author(s):  
T L Sørensen ◽  
F Sellebjerg
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Chemokine Receptor ◽  
Cd8 T Cells ◽  
Chemokine Receptors ◽  
Cxcr3 Expression ◽  
Selective Suppression ◽  
Relapsing Remitting ◽  
Relapsing Remitting Multiple Sclerosis

We studied the expression of chemokine receptors CCR1, CCR2, CCR3, CCR5, and CXCR3 on CD4 and CD8 positive T cells, and on CD14 positive monocytes in blood from 10 patients with relapsing-remitting multiple sclerosis (MS) at initiation of interferon (IFN)- βtreatment, after 1 month and after 3 months of treatment. It was found that the expression of CXCR3 on CD4+ and CD8+ T cells was significantly reduced after 3 months of treatment. The expression of other receptors was unaltered. Since CXCR3 cells are enriched in cerebrospinal fluid (CSF), and are detected in lesion material in MS this may represent an important mode of action of interferon- βin MS.

IFNβ-1a therapy for multiple sclerosis expands regulatory CD8+ T cells and decreases memory CD8+ subset: A longitudinal 1-year study

2010 ◽  
Vol 134 (2) ◽  
pp. 148-157 ◽  
Author(s):  
Carol Aristimuño ◽  
Clara de Andrés ◽  
Manuel Bartolomé ◽  
Virginia de las Heras ◽  
Ma. Luisa Martínez-Ginés ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cd8 T Cells

Multiple sclerosis and optic neuritis: CCR5 and CXCR3 expressing T cells are augmented in blood and cerebrospinal fluid

2002 ◽  
Vol 249 (6) ◽  
pp. 723-729 ◽  
Author(s):  
Natalia Teleshova ◽  
Mikhail Pashenkov ◽  
Yu-Min Huang ◽  
Mats Söderström ◽  
Pia Kivisäkk ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Optic Neuritis
Sign in / Sign up

Export Citation Format

Share Document