Clinical characteristics of Restless legs syndrome in patients with Parkinson's disease

2006 ◽  
Vol 250 (1-2) ◽  
pp. 39-44 ◽  
Author(s):  
Takashi Nomura ◽  
Yuichi Inoue ◽  
Kenji Nakashima
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Clinical Characteristics ◽  
Restless Legs

Clinical characteristics of leg restlessness in Parkinson's disease compared with idiopathic Restless Legs Syndrome

2015 ◽  
Vol 357 (1-2) ◽  
pp. 109-114 ◽  
Author(s):  
Xiao-Ying Zhu ◽  
Ye Liu ◽  
Xiao-Jin Zhang ◽  
Wen-Hao Yang ◽  
Ya Feng ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Clinical Characteristics ◽  
Restless Legs

Prevalence and clinical characteristics of restless legs syndrome in Japanese patients with Parkinson's disease

2005 ◽  
Vol 21 (3) ◽  
pp. 380-384 ◽  
Author(s):  
Takashi Nomura ◽  
Yuichi Inoue ◽  
Masahiro Miyake ◽  
Kenichi Yasui ◽  
Kenji Nakashima
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Clinical Characteristics ◽  
Japanese Patients ◽  
Restless Legs

scholarly journals Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations

2010 ◽  
Vol 68 (6) ◽  
pp. 869-872 ◽  
Author(s):  
Tiago Machado Guerreiro ◽  
Danilo Ryuko Cândido Nishikawa ◽  
Lis Campos Ferreira ◽  
Hyder Aragão de Melo ◽  
Roberto César Pereira do Prado
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Biochemical Parameters ◽  
Clinical Characteristics ◽  
Dopaminergic Drugs ◽  
Restless Legs ◽  
High Prevalence ◽  
Laboratory Variables ◽  
Secondary Causes

Restless legs syndrome (RLS) is a neurological disorder that responds to dopaminergic drugs, indicating a common pathophysiology with Parkinson's disease (PD). The prevalence of RLS was estimated in a group of PD patients and its clinical and biochemical characteristics were analysed. Forty-eight patients with PD were evaluated into two groups, with and without RLS. Clinical characteristics assessed in both groups were age, gender, duration of PD, Hoehn and Yahr, and Schwab and England scales. Laboratory variables such as hemoglobin, s-iron, s-ferritin and creatinine were obtained. The prevalence of RLS was 18.75%. No significant differences regarding clinical variables and biochemical parameters were observed. The high prevalence of RLS found in PD patients suggests the concept of a common etiological link and it seems that secondary causes did not play a central role in the pathophysiology of RLS in this group of parkinsonian patients.

Psycho-behavioral profile of parkinson's disease patients with restless legs syndrome/Willis-Ekbom disease

2017 ◽  
Vol 40 ◽  
pp. e92-e93
Author(s):  
A. Marques ◽  
M. Figorilli ◽  
B. Pereira ◽  
P. Beudin ◽  
T. Vidal ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Behavioral Profile ◽  
Restless Legs

Prevalence and clinical profile of restless legs syndrome in Parkinson's disease

2010 ◽  
Vol 25 (13) ◽  
pp. 2142-2147 ◽  
Author(s):  
Dagmar Verbaan ◽  
Stephanie M. van Rooden ◽  
Jacobus J. van Hilten ◽  
Roselyne M. Rijsman
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Clinical Profile ◽  
Restless Legs

scholarly journals Restless legs syndrome in Parkinson's disease and increased cardiovascular risk

2018 ◽  
Vol 76 (11) ◽  
pp. 731-735 ◽  
Author(s):  
Maren de Moraes e Silva ◽  
Cezar Henrique Lorenzi ◽  
Blenda Barreto Schneider ◽  
Catherine Enk Fischer Seidel ◽  
Isabela Salomé ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cardiovascular Risk ◽  
Restless Legs Syndrome ◽  
Protective Factor ◽  
Risk Scores ◽  
Dopaminergic Transmission ◽  
Restless Legs ◽  
Cardiovascular Comorbidities ◽  
Framingham Risk

ABSTRACT Restless legs syndrome (RLS) is a disorder commonly found in patients with Parkinson's disease, with descriptions for both conditions impairing dopaminergic transmission in central nervous system. Previous studies in varied populations indicate an association between the presence of RLS and increased cardiovascular risk and, so far, there are no consistent studies of this association in Parkinson's disease. Objective: To analyze the influence of RLS on cardiovascular risk in patients with Parkinson's disease. Methods: We reviewed the medical records of 202 patients diagnosed with Parkinson's disease and verified the presence of RLS, cardiovascular comorbidities, blood pressure measurements, lipid profiles and Framingham Risk Scores. Results: Statistically significant higher values of total cholesterol were found for the RLS group (mean 216.6 mg/dL), as well as for LDL cholesterol (mean 145 mg/dL). No statistical difference was found among the other factors. Conclusion: Patients with Parkinson's disease and RLS have a higher prevalence of dyslipidemia than patients without RLS, suggesting a correlation between restless legs and hyperlipidemia. It is questioned whether the dopaminergic substrate is the main factor in the genesis of the syndrome, as even with the use of dopaminergic agonists by both groups, it was possible to observe differences between groups. The hypothesis of the real interference of the syndrome treatment as a protective factor for cardiovascular risk was generated.

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