scholarly journals Association of breaks in sedentary time with physical functional loss in osteoarthritis initiative

2015 ◽  
Vol 23 ◽  
pp. A27-A28
Author(s):  
J. Lee ◽  
J. Song ◽  
R.W. Chang ◽  
P.A. Semanik ◽  
L.S. Ehrlich-Jones ◽  
...  
2019 ◽  
Vol 120 (1) ◽  
pp. 171-179 ◽  
Author(s):  
Aye C. Paing ◽  
Kathryn A. McMillan ◽  
Alison F. Kirk ◽  
Andrew Collier ◽  
Allan Hewitt ◽  
...  

Abstract Purpose To investigate how the pattern of sedentary behaviour affects intra-day glucose regulation in type 2 diabetes. Methods This intensive longitudinal study was conducted in 37 participants with type 2 diabetes (age, 62.8 ± 10.5 years). Glucose and sedentary behaviour/physical activity were assessed with a continuous glucose monitoring (Abbott FreeStyle Libre) and an activity monitor (activPAL3) for 14 days. Multiple regression models with generalised estimating equations (GEEs) approach were used to assess the associations of sedentary time and breaks in sedentary time with pre-breakfast glucose, pre-lunch glucose, pre-dinner glucose, post-breakfast glucose, post-lunch glucose, post-dinner glucose, bedtime glucose, the dawn phenomenon, time in target glucose range (TIR, glucose 3.9–10 mmol/L) and time above target glucose range (TAR, glucose > 10 mmol/L). Results Sedentary time was associated with higher pre-breakfast glucose (p = 0.001), pre-dinner glucose (p < 0.001), post-lunch glucose (p = 0.005), post-dinner glucose (p = 0.013) and the dawn phenomenon (p < 0.001). Breaks in sedentary time were associated with lower pre-breakfast glucose (p = 0.023), pre-dinner glucose (p = 0.023), post-breakfast glucose (p < 0.001) and the dawn phenomenon (p = 0.004). The association between sedentary time and less TIR (p = 0.022) and the association between breaks in sedentary time and more TIR (p = 0.001) were also observed. Conclusions Reducing sedentary time and promoting breaks in sedentary time could be clinically relevant to improve intra-day glucose regulation in type 2 diabetes.


AGE ◽  
2015 ◽  
Vol 37 (2) ◽  
Author(s):  
Pedro B. Júdice ◽  
Analiza M. Silva ◽  
Diana A. Santos ◽  
Fátima Baptista ◽  
Luís B. Sardinha

2014 ◽  
Vol 26 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Xanne Janssen ◽  
Dylan P. Cliff ◽  
John J. Reilly ◽  
Trina Hinkley ◽  
Rachel A. Jones ◽  
...  

2019 ◽  
Author(s):  
Bo-Huei Huang ◽  
Mark Hamer ◽  
Sebastien Chastin ◽  
Annemarie Koster ◽  
Natalie Pearson ◽  
...  

AbstractObjectiveTo examine the independent and joint associations thigh-worn accelerometry assessed sedentary time and moderate to vigorous physical activity with cardiometabolic health markers.DesignCross-sectional study embedded in the age-46 wave an established birth cohort, the 1970 British Birth Cohort.SettingPopulation-based sample from Great Britain (England, Scotland, and Wales).MethodsOutcome measures included: body mass index, waist-to-hip ratio, blood pressure, glycated hemoglobin, high-density lipoprotein cholesterol, total cholesterol, triglycerides, and c-reactive protein. Sedentary behavior and other physical activity exposures, recorded by a thigh-worn activPAL3 accelerometry, included: daily sedentary time, breaks in sedentary time, daily time spent in moderate-to-vigorous physical activity. Multiple linear regression analyses, multiple logistic regression analyses, and general linear models were conducted as applicable.Results4,634 participants were available for the final analysis. After adjusting for potential confounders and moderate-to-vigorous physical activity, daily sedentary time was positively associated with triglycerides (β=0.052 [0.015, 0.089]) and inversely associated with high-density lipoprotein cholesterol (β=-0.015 [-0.022, -0.010]). Daily prolonged sedentary time (≥ 60 minutes) was positively associated with both glycated hemoglobin and log-transformed c-reactive protein (β=0.240 [0.030, 0.440] and 0.026 [0.007, 0.045], respectively) and inversely associated with systolic blood pressure and high-density lipoprotein cholesterol (β=-0.450 [-0.760, -0.150] and -0.013 [-0.022, -0.003], respectively). After adjusting for potential confounders and daily sedentary time, daily breaks in sedentary time were inversely associated with glycated hemoglobin (β=-0.020 [-0.037, -0.003]), and positively associated with both triglycerides and systolic blood pressure (β=0.006 [0.002, 0.010] and 0.030 [0.002, 0.050], respectively). The joint associations of prolonged sedentary time and moderate-to-vigorous physical activity with the prevalence of diabetes were not statistically significant.ConclusionProlonged sedentary time (≥ 60 minutes) and daily breaks in sedentary time were deleteriously associated with glycated hemoglobin, although we found no evidence that there were joint moderate-to-vigorous physical activity and sitting associations.


2016 ◽  
Vol 48 (12) ◽  
pp. 2495-2502 ◽  
Author(s):  
NABEHA S. A. HAWARI ◽  
IQBAL AL-SHAYJI ◽  
JOHN WILSON ◽  
JASON M. R. GILL

Diabetologia ◽  
2011 ◽  
Vol 55 (3) ◽  
pp. 589-599 ◽  
Author(s):  
A. R. Cooper ◽  
S. Sebire ◽  
A. A. Montgomery ◽  
T. J. Peters ◽  
D. J. Sharp ◽  
...  

2017 ◽  
Vol 98 (12) ◽  
pp. 2485-2490 ◽  
Author(s):  
Daniel Pinto ◽  
Jing Song ◽  
Jungwha Lee ◽  
Rowland W. Chang ◽  
Pamela A. Semanik ◽  
...  

2018 ◽  
Author(s):  
Dustin S. Kehler ◽  
Andrew N. Stammers ◽  
Laura Meade ◽  
Alex Edye-Mazowita ◽  
Jacqueline L. Hay ◽  
...  

UNSTRUCTURED Extended bouts of sedentary time are common in the modern working environment. As such, effective interventions are needed to counter the adverse health effects of sitting. We developed a theory-informed, mobile health app (i.e. the ENCOURAGE App) designed to interrupt occupational sitting time. The objective of our study is to investigate the effect of the ENCOURAGE App on the number of breaks in sedentary time taken throughout the day. This is a single-group, time series quasi-experiment evaluating the effect of the ENCOURAGE App on breaks in sedentary time. Data will be collected at baseline pre-intervention, 1-week, 1-month and repeated monthly for 6-months thereafter. We will recruit up to 300 individuals that have downloaded the app using an electronic, mobile consent form. The primary outcome of the study will examine a change in the number of breaks in sedentary time from baseline to one-month. We will also recruit a sub-sample of 60 individuals to collect objective data on physical activity and sedentary behaviour. As the modern working environment continues to promote a sedentary lifestyle, there is an urgent need to identify cost-effective solutions that can be scaled for both small and large organizations. This study aims to develop a novel mobile health app to support employees to reduce their sedentary time and become more physically active. The trial has been registered on ClinicalTrials.gov, a registry database of privately and publicly funded clinical research studies (NCT03403270).


2018 ◽  
Vol 12 ◽  
pp. 94-100 ◽  
Author(s):  
Aye C. Paing ◽  
Kathryn A. McMillan ◽  
Alison F. Kirk ◽  
Andrew Collier ◽  
Allan Hewitt ◽  
...  

Diabetes Care ◽  
2008 ◽  
Vol 31 (4) ◽  
pp. 661-666 ◽  
Author(s):  
G. N. Healy ◽  
D. W. Dunstan ◽  
J. Salmon ◽  
E. Cerin ◽  
J. E. Shaw ◽  
...  

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