Associations of breaks in sedentary time with abdominal obesity in Portuguese older adults

Abstract Background Cross-sectional evidence exists on the beneficial effects of breaks in sedentary time (BST) on frailty in older adults. Nonetheless, the longitudinal nature of these associations is unknown. This study aimed to investigate the direction and temporal order of the association between accelerometer-derived BST and frailty over time in older adults. Methods This longitudinal study analyzed a total of 186 older adults aged 67–90 (76.7 ± 3.9 years; 52.7% females) from the Toledo Study for Healthy Aging over a 4-year period. Number of daily BST was measured by accelerometry. Frailty was assessed with the Frailty Trait Scale. Multiple cross-lagged panel models were used to test the temporal and reciprocal relationship between BST and frailty. Results For those physically inactive (n = 126), our analyses revealed a reciprocal inverse relationship between BST and frailty, such as higher initial BST predicted lower levels of later frailty (standardized regression coefficient [β] = −0.150, 95% confidence interval [CI] = −0.281, −0.018; p < .05); as well as initial lower frailty levels predicted higher future BST (β = −0.161, 95% CI = −0.310, −0.011; p < .05). Conversely, no significant pathway was found in the active participants (n = 60). Conclusions In physically inactive older adults, the relationship between BST and frailty is bidirectional, while in active individuals no associations were found. This investigation provides preliminary longitudinal evidence that breaking-up sedentary time more often reduces frailty in those older adults who do not meet physical activity recommendations. Targeting frequent BST may bring a feasible approach to decrease the burden of frailty among more at-risk inactive older adults.

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Associations of Sedentary Time and Breaks in Sedentary Time With Disability in Instrumental Activities of Daily Living in Community-Dwelling Older Adults

Journal of Physical Activity and Health ◽

10.1123/jpah.2015-0090 ◽

2016 ◽

Vol 13 (3) ◽

pp. 303-309 ◽

Cited By ~ 13

Author(s):

Tao Chen ◽

Kenji Narazaki ◽

Yuka Haeuchi ◽

Sanmei Chen ◽

Takanori Honda ◽

...

Keyword(s):

Older Adults ◽

Activities Of Daily Living ◽

Daily Living ◽

Sedentary Time ◽

Functional Independence ◽

Community Dwelling ◽

Instrumental Activities ◽

Iadl Disability ◽

Breaks In Sedentary Time ◽

Community Dwelling Older Adults

Background:This cross-sectional study was performed to examine associations of objectively measured sedentary time (ST) and breaks in sedentary time (BST) with instrumental activities of daily living (IADL) disability in Japanese community-dwelling older adults.Methods:The sample comprised 1634 older adults (mean age: 73.3 y, men: 38.4%). Sedentary behavior was measured using a triaxial accelerometer. Disability was defined as inability in at least 1 of the IADL tasks using the Tokyo Metropolitan Institute of Gerontology Index of Competence.Results:After adjusting for potential confounders and moderate-to-vigorous physical activity (MVPA), longer ST was significantly associated with higher likelihood of IADL disability, whereas a greater number of BST was associated with lower likelihood of IADL disability. ST and BST remained statistically significant after mutual adjustment with odds ratio of 1.30 (95% confidence interval [CI)], 1.00–1.70) and 0.80 (95% CI, 0.65–0.99), respectively.Conclusions:This study first demonstrated that shorter ST and more BST were associated with lower risk of IADL disability independent of MVPA and that the association for ST was independent of BST and vice versa. These findings suggest not only total ST but also the manner in which it is accumulated may contribute to the maintenance of functional independence in older adults.

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Agreement of Sedentary Behavior Metrics Derived From Hip- and Thigh-Worn Accelerometers Among Older Adults: With Implications for Studying Physical and Cognitive Health

Journal for the Measurement of Physical Behaviour ◽

10.1123/jmpb.2020-0036 ◽

2021 ◽

Vol 4 (1) ◽

pp. 79-88

Author(s):

John Bellettiere ◽

Fatima Tuz-Zahra ◽

Jordan A. Carlson ◽

Nicola D. Ridgers ◽

Sandy Liles ◽

...

Keyword(s):

Older Adults ◽

Health Outcomes ◽

Sedentary Behavior ◽

Sedentary Time ◽

Statistical Significance ◽

Limits Of Agreement ◽

Cognitive Health ◽

Bout Duration ◽

Breaks In Sedentary Time ◽

Pearson Correlations

Little is known about how sedentary behavior (SB) metrics derived from hip- and thigh-worn accelerometers agree for older adults. Thigh-worn activPAL (AP) micro monitors were concurrently worn with hip-worn ActiGraph (AG) GT3X+ accelerometers (with SB measured using the 100 counts per minute [cpm] cut point; AG100cpm) by 953 older adults (age 77 ± 6.6, 54% women) for 4–7 days. Device agreement for sedentary time and five SB pattern metrics was assessed using mean error and correlations. Logistic regression tested associations with four health outcomes using standardized (i.e., z scores) and unstandardized SB metrics. Mean errors (AP − AG100cpm) and 95% limits of agreement were: sedentary time −54.7 [−223.4, 113.9] min/day; time in 30+ min bouts 77.6 [−74.8, 230.1] min/day; mean bout duration 5.9 [0.5, 11.4] min; usual bout duration 15.2 [0.4, 30] min; breaks in sedentary time −35.4 [−63.1, −7.6] breaks/day; and alpha −.5 [−.6, −.4]. Respective Pearson correlations were: .66, .78, .73, .79, .51, and .40. Concordance correlations were: .57, .67, .40, .50, .14, and .02. The statistical significance and direction of associations were identical for AG100cpm and AP metrics in 46 of 48 tests, though significant differences in the magnitude of odds ratios were observed among 13 of 24 tests for unstandardized and five of 24 for standardized SB metrics. Caution is needed when interpreting SB metrics and associations with health from AG100cpm due to the tendency for it to overestimate breaks in sedentary time relative to AP. However, high correlations between AP and AG100cpm measures and similar standardized associations with health outcomes suggest that studies using AG100cpm are useful, though not ideal, for studying SB in older adults.

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Impact of free-living pattern of sedentary behaviour on intra-day glucose regulation in type 2 diabetes

European Journal of Applied Physiology ◽

10.1007/s00421-019-04261-z ◽

2019 ◽

Vol 120 (1) ◽

pp. 171-179 ◽

Cited By ~ 1

Author(s):

Aye C. Paing ◽

Kathryn A. McMillan ◽

Alison F. Kirk ◽

Andrew Collier ◽

Allan Hewitt ◽

...

Keyword(s):

Type 2 Diabetes ◽

Sedentary Behaviour ◽

Sedentary Time ◽

Glucose Monitoring ◽

Glucose Regulation ◽

Dawn Phenomenon ◽

Freestyle Libre ◽

Breaks In Sedentary Time ◽

Target Glucose

Abstract Purpose To investigate how the pattern of sedentary behaviour affects intra-day glucose regulation in type 2 diabetes. Methods This intensive longitudinal study was conducted in 37 participants with type 2 diabetes (age, 62.8 ± 10.5 years). Glucose and sedentary behaviour/physical activity were assessed with a continuous glucose monitoring (Abbott FreeStyle Libre) and an activity monitor (activPAL3) for 14 days. Multiple regression models with generalised estimating equations (GEEs) approach were used to assess the associations of sedentary time and breaks in sedentary time with pre-breakfast glucose, pre-lunch glucose, pre-dinner glucose, post-breakfast glucose, post-lunch glucose, post-dinner glucose, bedtime glucose, the dawn phenomenon, time in target glucose range (TIR, glucose 3.9–10 mmol/L) and time above target glucose range (TAR, glucose > 10 mmol/L). Results Sedentary time was associated with higher pre-breakfast glucose (p = 0.001), pre-dinner glucose (p < 0.001), post-lunch glucose (p = 0.005), post-dinner glucose (p = 0.013) and the dawn phenomenon (p < 0.001). Breaks in sedentary time were associated with lower pre-breakfast glucose (p = 0.023), pre-dinner glucose (p = 0.023), post-breakfast glucose (p < 0.001) and the dawn phenomenon (p = 0.004). The association between sedentary time and less TIR (p = 0.022) and the association between breaks in sedentary time and more TIR (p = 0.001) were also observed. Conclusions Reducing sedentary time and promoting breaks in sedentary time could be clinically relevant to improve intra-day glucose regulation in type 2 diabetes.

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Short Physical Performance Battery (SPPB) score as a discriminator of dynapenic abdominal obesity among community-dwelling older adults

Geriatric Nursing ◽

10.1016/j.gerinurse.2021.02.016 ◽

2021 ◽

Vol 42 (2) ◽

pp. 467-472

Author(s):

Elane Priscila Rosa dos Santos ◽

Caroline Fátima Ribeiro Silva ◽

Daniela Gonçalves Ohara ◽

Areolino Pena Matos ◽

Ana Carolina Pereira Nunes Pinto ◽

...

Keyword(s):

Older Adults ◽

Physical Performance ◽

Abdominal Obesity ◽

Community Dwelling ◽

Short Physical Performance Battery ◽

Community Dwelling Older Adults

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Effects Of A Long-term Physical Activity Program On Accelerometry-based Sedentary Time In Older Adults

Medicine & Science in Sports & Exercise ◽

10.1249/01.mss.0000477849.39535.d3 ◽

2015 ◽

Vol 47 ◽

pp. 515-516

Author(s):

Amal A. Wanigatunga ◽

Walter T. Ambrosius ◽

Mary M. McDermott ◽

Abby C. King ◽

Roger A. Fielding ◽

...

Keyword(s):

Physical Activity ◽

Older Adults ◽

Sedentary Time ◽

Physical Activity Program ◽

Activity Program

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Determining accelerometer non-wear and sedentary time in midlife and older adults

Journal of Science and Medicine in Sport ◽

10.1016/j.jsams.2012.11.583 ◽

2012 ◽

Vol 15 ◽

pp. S240

Author(s):

S. Hooker ◽

B. Hutto ◽

S. Blair ◽

N. Colabianchi ◽

J. Vena ◽

...

Keyword(s):

Older Adults ◽

Sedentary Time

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All-cause mortality effects of replacing sedentary time with physical activity and sleeping using an isotemporal substitution model: a prospective study of 201,129 mid-aged and older adults

International Journal of Behavioral Nutrition and Physical Activity ◽

10.1186/s12966-015-0280-7 ◽

2015 ◽

Vol 12 (1) ◽

Cited By ~ 74

Author(s):

Emmanuel Stamatakis ◽

Kris Rogers ◽

Ding Ding ◽

David Berrigan ◽

Josephine Chau ◽

...

Keyword(s):

Physical Activity ◽

Older Adults ◽

Prospective Study ◽

Sedentary Time ◽

Substitution Model ◽

All Cause Mortality ◽

A Prospective Study

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Validation of ActivPAL Defined Sedentary Time and Breaks in Sedentary Time in 4- to 6-Year-Olds

Pediatric Exercise Science ◽

10.1123/pes.2013-0106 ◽

2014 ◽

Vol 26 (1) ◽

pp. 110-117 ◽

Cited By ~ 16

Author(s):

Xanne Janssen ◽

Dylan P. Cliff ◽

John J. Reilly ◽

Trina Hinkley ◽

Rachel A. Jones ◽

...

Keyword(s):

Sedentary Time ◽

Breaks In Sedentary Time

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Independent and Joint Associations of Sedentary Behavior and Physical Activity with Cardiometabolic Health Markers in the 1970 British Birth Cohort

10.1101/19009738 ◽

2019 ◽

Author(s):

Bo-Huei Huang ◽

Mark Hamer ◽

Sebastien Chastin ◽

Annemarie Koster ◽

Natalie Pearson ◽

...

Keyword(s):

Physical Activity ◽

High Density Lipoprotein ◽

High Density Lipoprotein Cholesterol ◽

Sedentary Time ◽

Glycated Hemoglobin ◽

Vigorous Physical Activity ◽

Density Lipoprotein ◽

High Density ◽

Breaks In Sedentary Time ◽

Joint Associations

AbstractObjectiveTo examine the independent and joint associations thigh-worn accelerometry assessed sedentary time and moderate to vigorous physical activity with cardiometabolic health markers.DesignCross-sectional study embedded in the age-46 wave an established birth cohort, the 1970 British Birth Cohort.SettingPopulation-based sample from Great Britain (England, Scotland, and Wales).MethodsOutcome measures included: body mass index, waist-to-hip ratio, blood pressure, glycated hemoglobin, high-density lipoprotein cholesterol, total cholesterol, triglycerides, and c-reactive protein. Sedentary behavior and other physical activity exposures, recorded by a thigh-worn activPAL3 accelerometry, included: daily sedentary time, breaks in sedentary time, daily time spent in moderate-to-vigorous physical activity. Multiple linear regression analyses, multiple logistic regression analyses, and general linear models were conducted as applicable.Results4,634 participants were available for the final analysis. After adjusting for potential confounders and moderate-to-vigorous physical activity, daily sedentary time was positively associated with triglycerides (β=0.052 [0.015, 0.089]) and inversely associated with high-density lipoprotein cholesterol (β=-0.015 [-0.022, -0.010]). Daily prolonged sedentary time (≥ 60 minutes) was positively associated with both glycated hemoglobin and log-transformed c-reactive protein (β=0.240 [0.030, 0.440] and 0.026 [0.007, 0.045], respectively) and inversely associated with systolic blood pressure and high-density lipoprotein cholesterol (β=-0.450 [-0.760, -0.150] and -0.013 [-0.022, -0.003], respectively). After adjusting for potential confounders and daily sedentary time, daily breaks in sedentary time were inversely associated with glycated hemoglobin (β=-0.020 [-0.037, -0.003]), and positively associated with both triglycerides and systolic blood pressure (β=0.006 [0.002, 0.010] and 0.030 [0.002, 0.050], respectively). The joint associations of prolonged sedentary time and moderate-to-vigorous physical activity with the prevalence of diabetes were not statistically significant.ConclusionProlonged sedentary time (≥ 60 minutes) and daily breaks in sedentary time were deleteriously associated with glycated hemoglobin, although we found no evidence that there were joint moderate-to-vigorous physical activity and sitting associations.

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