Touch Imprint Cytology: Can It Serve as an Alternative to Frozen Section in Intraoperative Assessment of Cervical Metastasis in Oral Squamous Cell Carcinoma?

2019 ◽  
Vol 77 (5) ◽  
pp. 994-999 ◽  
Author(s):  
Anchal Agarwal ◽  
Nitin Bhola ◽  
Rajanikanth Kambala ◽  
Rajiv M. Borle
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Frozen Section ◽  
Imprint Cytology ◽  
Cervical Metastasis ◽  
Intraoperative Assessment ◽  
Touch Imprint Cytology

scholarly journals Intraoperative Assessment of Surgical Margins of Oral Squamous Cell Carcinoma Using Frozen Sections: A Practical Clinicopathological Management for Recurrences

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Shun Miyota ◽  
Takanori Kobayashi ◽  
Tatsuya Abé ◽  
Hisashi Miyajima ◽  
Masaki Nagata ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Free Group ◽  
Squamous Cell ◽  
Frozen Section ◽  
Surgical Margins ◽  
Clinical Issue ◽  
Intraoperative Assessment ◽  
Relapse Group

Background. Local recurrence remains a challenging clinical issue for the treatment of oral squamous cell carcinoma (SCC). We analyzed retrospectively how effective the frozen section technique (FS) was against recurrences of oral SCC.Methods. We screened 343 surgical samples from 236 patients who had oral SCC, carcinoma in situ (CIS), or epithelial dysplasia, and we followed up their clinical outcomes for at least 5 years. Histopathological states of surgical margins were compared between FS and surgical materials in relapse and relapse-free groups, respectively.Results. Among the 236 patients, 191 were classified into the relapse-free group, and 45 into the relapse group. FS was more frequently performed in the relapse-free group (128/191) than in the relapse group (83/152). Histopathologically, moderate dysplasia or CIS (borderline malignancies) and SCC were recognized in 55 samples of the relapse-free group and in 57 of the relapse group. For those surgical margins with borderline malignancies, additional incisions were performed in 38 of the 55 relapse-free cases, which reduced to 20 from the 38 margins with borderline malignancies (47.4% reduction), and in 39 of the 57 relapse cases, which reduced to only 3 of 39 (7.7% reduction).Conclusions. The intraoperative assessment of surgical margins by FS is essential in preventing recurrences of oral mucosal malignancies.

Touch Imprint Cytology: A Rapid and Accurate Method for Diagnosis of Oral Cancer

2019 ◽  
Vol 63 (5) ◽  
pp. 411-416
Author(s):  
Amit Kumar Adhya ◽  
Madhabananda Kar ◽  
Ranjan Mohanty
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cost Effective ◽  
Accurate Method ◽  
Imprint Cytology ◽  
Cytologic Examination ◽  
Touch Imprint Cytology

Objectives: Touch imprint cytology (TIC) is a rapid and cheap method and can be used as an adjunct to biopsy for the evaluation of suspected malignancy. We evaluated the advantages and limitations of TIC for the preoperative diagnosis of oral squamous cell carcinoma. Study Design: We used 280 incisional biopsies of clinically suspected oral squamous cell carcinoma and compared TIC diagnosis to histopathological sections. The sensitivity, specificity, and diagnostic accuracy of TIC were evaluated. Results: A total of 201 (82.5%) cases were diagnosed as malignant, 22 (7.9%) cases were diagnosed as suspicious of malignancy, and 54 (19.3%) cases as benign/negative on TIC. The overall sensitivity of TIC was 98.2%, specificity was 89.3%, the positive-predictive value 97.3%, and the negative-predictive value was 92.6%. The accuracy of the test was 96.4%. Conclusions: TIC is an accurate, simple, rapid, and cost-effective method that aids the diagnosis of oral squamous cell carcinoma but does not replace incisional biopsy. The cytologic examination of imprints of biopsies also helps determine the adequacy of the specimen for histologic examination.

scholarly journals A comparative analysis of toluidine blue with frozen section in oral squamous cell carcinoma

2012 ◽  
Vol 10 (1) ◽  
Author(s):  
Montasir Junaid ◽  
Moaz M Choudhary ◽  
Zain A Sobani ◽  
Ghulam Murtaza ◽  
Sadaf Qadeer ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Comparative Analysis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Toluidine Blue ◽  
Frozen Section

scholarly journals Study of Frozen Section Biopsy as Intraoperative Procedure for Oral Squamous Cell Carcinoma in BSMMU

2009 ◽  
Vol 2 (1) ◽  
Author(s):  
Swapan Kumar Mondoul ◽  
Farzana Hakim ◽  
Mahmuda Akhter ◽  
Shakhawat Hossain ◽  
Ashim Ranjan Barua ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Frozen Section
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