Diagnostic utility of touch imprint cytology for intraoperative assessment of surgical margins and sentinel lymph nodes in oral squamous cell carcinoma patients using four different cytological stains

2019 ◽  
Vol 48 (2) ◽  
pp. 101-110 ◽  
Author(s):  
Aiman Zafar ◽  
Herald J. Sherlin ◽  
Gifrina Jayaraj ◽  
Pratibha Ramani ◽  
Kanchi R Don ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Sentinel Lymph Nodes ◽  
Surgical Margins ◽  
Diagnostic Utility ◽  
Imprint Cytology ◽  
Touch Imprint Cytology

Pathologic evaluation of sentinel lymph nodes in oral squamous cell carcinoma

Head & Neck ◽  
2010 ◽  
Vol 32 (11) ◽  
pp. 1437-1443 ◽  
Author(s):  
Nirav P. Trivedi ◽  
Hiran Kattilaparambil Ravindran ◽  
Shanmugham Sundram ◽  
Subramania Iyer ◽  
Vikram Kekatpure ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Sentinel Lymph Nodes ◽  
Pathologic Evaluation

Touch Imprint Cytology: A Rapid and Accurate Method for Diagnosis of Oral Cancer

2019 ◽  
Vol 63 (5) ◽  
pp. 411-416
Author(s):  
Amit Kumar Adhya ◽  
Madhabananda Kar ◽  
Ranjan Mohanty
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cost Effective ◽  
Accurate Method ◽  
Imprint Cytology ◽  
Cytologic Examination ◽  
Touch Imprint Cytology

Objectives: Touch imprint cytology (TIC) is a rapid and cheap method and can be used as an adjunct to biopsy for the evaluation of suspected malignancy. We evaluated the advantages and limitations of TIC for the preoperative diagnosis of oral squamous cell carcinoma. Study Design: We used 280 incisional biopsies of clinically suspected oral squamous cell carcinoma and compared TIC diagnosis to histopathological sections. The sensitivity, specificity, and diagnostic accuracy of TIC were evaluated. Results: A total of 201 (82.5%) cases were diagnosed as malignant, 22 (7.9%) cases were diagnosed as suspicious of malignancy, and 54 (19.3%) cases as benign/negative on TIC. The overall sensitivity of TIC was 98.2%, specificity was 89.3%, the positive-predictive value 97.3%, and the negative-predictive value was 92.6%. The accuracy of the test was 96.4%. Conclusions: TIC is an accurate, simple, rapid, and cost-effective method that aids the diagnosis of oral squamous cell carcinoma but does not replace incisional biopsy. The cytologic examination of imprints of biopsies also helps determine the adequacy of the specimen for histologic examination.

scholarly journals Primary Tumor-Secreted Lymphangiogenic Factors Induce Pre-Metastatic Lymphvascular Niche Formation at Sentinel Lymph Nodes in Oral Squamous Cell Carcinoma

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0144056 ◽  
Author(s):  
Naohiro Wakisaka ◽  
Yasuhisa Hasegawa ◽  
Seiichi Yoshimoto ◽  
Kouki Miura ◽  
Akihiro Shiotani ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Sentinel Lymph Nodes ◽  
Niche Formation

Role of Clinical Palpation in Evaluation of Cervical Lymph Node in Oral Squamous Cell Carcinoma

2013 ◽  
Vol 1 (2) ◽  
pp. 02-06
Author(s):  
SM Anwar Sadat ◽  
Sufia Nasrin Rita ◽  
Shoma Banik ◽  
Md Nazmul Hasan Khandker ◽  
Md Mahfuz Hossain ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cervical Lymph Node ◽  
Betel Quid ◽  
Cervical Lymph Nodes

A cross sectional study of 29 cases of oral squamous cell carcinoma with or without  cervical lymph node metastasis was done among Bangladeshi patients from January 2006 to December 2007. Majority of the study subjects (34.5%) belonged to the age group of 40-49 years. 58.6% of the study subjects were male, while remaining 41.4% of them were female. 51.7% of the lesions were located in the alveolar ridge where the other common sites were buccal mucosa (27.6%) and retro molar area (13.8%). Half of the study subjects (51.7%) were habituated to betel quid chewing followed by 37.9% and 10.3% were habituated to smoking and betel quid-smoking respectively. Grade I lesions was most prevalent (75.9%) in the study subjects.  Majority of cases presented with Stage IV lesions (55.2%). The sensitivity, specificity, positive predictive value, negative predictive value & accuracy of clinical palpation method for determining metastatic cervical lymph nodes were 93.33%, 64.29%, 73.68%, 90% and 79.3% respectively. Careful and repeated clinical palpation plays important role in evaluation of cervical lymph nodes though several modern techniques may help additionally in the management of oral cancer.DOI: http://dx.doi.org/10.3329/updcj.v1i2.13978 Update Dent. Coll. j. 2011: 1(2): 02-06

Sign in / Sign up

Export Citation Format

Share Document