Development and in vitro evaluation of BSA-coated liposomes containing Zn (II) phthalocyanine-containing ferrocene groups for photodynamic therapy of lung cancer

2020 ◽  
Vol 925 ◽  
pp. 121469
Author(s):  
Özlem Çoban ◽  
Burak Barut ◽  
Can Özgür Yalçın ◽  
Arzu Özel ◽  
Zekeriya Bıyıklıoğlu
Keyword(s):  
Lung Cancer ◽  
Photodynamic Therapy ◽  
In Vitro Evaluation

In vitro photodynamic therapy of human lung cancer: Investigation of dose-rate effects

Lung Cancer ◽  
1990 ◽  
Vol 6 (1-2) ◽  
pp. 63
Author(s):  
W Matthews ◽  
J Cook ◽  
JB Mitchell ◽  
RR Perry ◽  
S Evans ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Photodynamic Therapy ◽  
Dose Rate ◽  
Human Lung ◽  
Human Lung Cancer ◽  
Dose Rate Effects ◽  
Rate Effects

In vitro photodynamic therapy of human lung cancer

1989 ◽  
Vol 47 (3) ◽  
pp. 276-281 ◽  
Author(s):  
Wilbert Matthews ◽  
Walter Rizzoni ◽  
James Mitchell ◽  
Angelo Russo ◽  
Harvey Pass
Keyword(s):  
Lung Cancer ◽  
Photodynamic Therapy ◽  
Human Lung ◽  
Human Lung Cancer

scholarly journals TLD1433-Mediated Photodynamic Therapy with an Optical Surface Applicator in the Treatment of Lung Cancer Cells In Vitro

2020 ◽  
Vol 13 (7) ◽  
pp. 137 ◽  
Author(s):  
Sarah Chamberlain ◽  
Houston D. Cole ◽  
John Roque ◽  
David Bellnier ◽  
Sherri A. McFarland ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Photodynamic Therapy ◽  
Cell Viability ◽  
Light Propagation ◽  
Residual Disease ◽  
Red Light ◽  
Optical Surface ◽  
Light Fluence ◽  
532 Nm

Intra-operative photodynamic therapy (IO-PDT) in combination with surgery for the treatment of non-small cell lung cancer and malignant pleural mesothelioma has shown promise in improving overall survival in patients. Here, we developed a PDT platform consisting of a ruthenium-based photosensitizer (TLD1433) activated by an optical surface applicator (OSA) for the management of residual disease. Human lung adenocarcinoma (A549) cell viability was assessed after treatment with TLD1433-mediated PDT illuminated with either 532- or 630-nm light with a micro-lens laser fiber. This TLD1433-mediated PDT induced an EC50 of 1.98 μM (J/cm2) and 4807 μM (J/cm2) for green and red light, respectively. Cells were then treated with 10 µM TLD1433 in a 96-well plate with the OSA using two 2-cm radial diffusers, each transmitted 532 nm light at 50 mW/cm for 278 s. Monte Carlo simulations of the surface light propagation from the OSA computed light fluence (J/cm2) and irradiance (mW/cm2) distribution. In regions where 100% loss in cell viability was measured, the simulations suggest that >20 J/cm2 of 532 nm was delivered. Our studies indicate that TLD1433-mediated PDT with the OSA and light simulations have the potential to become a platform for treatment planning for IO-PDT.

Polylactide-Based Block Copolymeric Micelles Loaded with Chlorin e6 for Photodynamic Therapy: In Vitro Evaluation in Monolayer and 3D Spheroid Models

2017 ◽  
Vol 14 (11) ◽  
pp. 3789-3800 ◽  
Author(s):  
Preeti Kumari ◽  
Shreya Jain ◽  
Balaram Ghosh ◽  
Vladimir Zorin ◽  
Swati Biswas
Keyword(s):  
Photodynamic Therapy ◽  
Chlorin E6 ◽  
In Vitro Evaluation

Screening and In Vitro Evaluation of Mucoadhesive Thermoresponsive System Containing Methylene Blue for Local Photodynamic Therapy of Colorectal Cancer

2015 ◽  
Vol 33 (3) ◽  
pp. 776-791 ◽  
Author(s):  
Fernanda Belincanta Borghi-Pangoni ◽  
Mariana Volpato Junqueira ◽  
Sabrina Barbosa de Souza Ferreira ◽  
Larissa Lachi Silva ◽  
Bruno Ribeiro Rabello ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Methylene Blue ◽  
Photodynamic Therapy ◽  
In Vitro Evaluation

scholarly journals In Vitro Evaluation of Anticancer Effects of Lung Cancer Chemotherapy Regimens

2010 ◽  
Vol 36 (4) ◽  
pp. 220-226 ◽  
Author(s):  
Yukiko Saito ◽  
Takeshi Hirano ◽  
Hiromitsu Oki ◽  
Kumiko Kasashi ◽  
Mitsuru Sugawara ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Chemotherapy ◽  
In Vitro Evaluation ◽  
Anticancer Effects

scholarly journals Development, optimization and in vitro evaluation of oxaliplatin loaded nanoparticles in non-small cell lung cancer

2020 ◽  
Vol 28 (2) ◽  
pp. 673-684
Author(s):  
Ozgur Esim ◽  
Nurgul K. Bakirhan ◽  
Nuray Yildirim ◽  
Meral Sarper ◽  
Ayhan Savaser ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
In Vitro Evaluation

Synthesis and In Vitro Evaluation of Anti‐Leukemic Potency of Some Novel Azo‐Naphthol Dyes Conjugated with Metal Nanoparticles as Photosensitizers for Photodynamic Therapy

2020 ◽  
Vol 5 (28) ◽  
pp. 8609-8615 ◽  
Author(s):  
Mohamed E. Khalifa ◽  
Elham A. Elkhawass ◽  
Masayuki Ninomiya ◽  
Kaori Tanaka ◽  
Mamoru Koketsu
Keyword(s):  
Photodynamic Therapy ◽  
Metal Nanoparticles ◽  
In Vitro Evaluation
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