Liquid chromatography–mass spectrometry analysis of diethylcarbamazine in human plasma for clinical pharmacokinetic studies

2014 ◽  
Vol 98 ◽  
pp. 307-310 ◽  
Author(s):  
Mark S. Schmidt ◽  
Christopher L. King ◽  
Edward K. Thomsen ◽  
Peter M. Siba ◽  
Nelly Sanuku ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Human Plasma ◽  
Clinical Pharmacokinetic ◽  
Mass Spectrometry Analysis ◽  
Pharmacokinetic Studies ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Analysis ◽  
Chromatography Mass Spectrometry

scholarly journals Liquid chromatography–mass spectrometry analysis of dyes formed by in situ oxidative methods then purified by absorption and extraction from hair wefts

2020 ◽  
pp. 174751982097862
Author(s):  
M John Plater ◽  
Andrea Raab
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Complex Mixture ◽  
Ammonium Salts ◽  
Mass Spectrometry Analysis ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Analysis ◽  
Chromatography Mass Spectrometry ◽  
Didecyldimethylammonium Chloride

The dye mixtures formed from three commercial hair colour formers were purified by absorption onto human hair wefts, washed and dried, extracted with dichloromethane:trifluoroacetic acid (75:25) and then analysed by liquid chromatography–mass spectrometry. Only 1–2 dyes were identified from each complex mixture of commercial aromatic amines along with a broad UV absorption mainly consisting of mixtures of quaternary ammonium salts from shampoos and some surfactants. Mecetronium ethyl sulfate and didecyldimethylammonium chloride were the main ammonium salts.

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