scholarly journals Neonatal screening: 9% of children with filter paper thyroid-stimulating hormone levels between 5 and 10 μIU/mL have congenital hypothyroidism

2017 ◽  
Vol 93 (6) ◽  
pp. 649-654 ◽  
Author(s):  
Flávia C. Christensen-Adad ◽  
Carolina T. Mendes-dos-Santos ◽  
Maura M.F. Goto ◽  
Letícia E. Sewaybricker ◽  
Lília F.R. D'Souza-Li ◽  
...  
2017 ◽  
Vol 93 (6) ◽  
pp. 649-654
Author(s):  
Flávia C. Christensen‐Adad ◽  
Carolina T. Mendes‐dos‐Santos ◽  
Maura M.F. Goto ◽  
Letícia E. Sewaybricker ◽  
Lília F.R. D'Souza‐Li ◽  
...  

2018 ◽  
Vol 55 (12) ◽  
pp. 1059-1061 ◽  
Author(s):  
Maria Scavone ◽  
Elena Carboni ◽  
Ettore Stefanelli ◽  
Giusy Romano ◽  
Anna Vero ◽  
...  

2009 ◽  
Vol 05 (0) ◽  
pp. 64
Author(s):  
Luca Persani ◽  
Davide Calebiro ◽  
◽  

The consequences of using low blood-spot thyroid-stimulating hormone (b-TSH) cut-off values for newborn screening of congenital hypothyroidism (CH) are largely unknown. Therefore, the impact on CH epidemiology and classification generated by the introduction in our Italian region of a low b-TSH cut-off during 1999–2005 was retrospectively examined. This work was recently performed in collaboration with the Laboratory for Neonatal Screening and the Principal Follow-up Centre of the Lombardy region. The incidence of CH in this Italian population was 1:1,446 live births, with a predominance of functional over morphogenetic defects. The use of low b-TSH cut-offs allowed the detection of an unsuspected number of children with neonatal hypothyroidism, evolving to mild permanent thyroid dysfunction later in life. Premature birth was associated with a three- to five-fold increased risk of CH with glandin situ.


2015 ◽  
Vol 7 (4) ◽  
pp. 307-311 ◽  
Author(s):  
Taliha Öner ◽  
Rahmi Özdemir ◽  
Önder Doksöz ◽  
Yılmaz Yozgat ◽  
Cem Karadeniz ◽  
...  

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