Measure twice and cut once: Comparing endoscopy and 3D cloacagram for the common channel and urethral measurements in patients with cloacal malformations

2020 ◽  
Vol 55 (2) ◽  
pp. 257-260 ◽  
Author(s):  
Devin R. Halleran ◽  
Caitlin A. Smith ◽  
Megan K. Fuller ◽  
Megan M. Durhm ◽  
Belinda Dickie ◽  
...  
2019 ◽  
Vol 03 (04) ◽  
pp. 333-336
Author(s):  
Caitlin A. Smith ◽  
Manish Patel ◽  
Kevin S.H. Koo

AbstractCloaca is a rare complex anorectal malformation in female patients where the urinary, gynecologic, and gastrointestinal tracts empty through a single pathway, known as the common channel. Previously, cloacas were measured through endoscopic evaluation alone. In recent years, radiographic imaging of the cloaca with a 3D cloacagram, has been a valuable tool for the characterization of the specific anatomical variables in each cloaca, and provides additional information that is beneficial for the preoperative surgical planning. This article reviews the embryology of cloaca, as well as the classification, noninvasive imaging, cloacagram protocol, and surgical intervention.


Author(s):  
Mohamed Abdelmalak Abokandil ◽  
Saber Waheeb ◽  
Gamal Eltagy ◽  
Ahmad Khairi ◽  
Yasmine Farghaly ◽  
...  

Abstract Introduction This research aimed to study the relationship between common channel length and urethral length in cloaca patients by different diagnostic modalities and the ability of common channel length to predict the urethral length. Materials and Methods The study was conducted on 30 cases of cloaca managed at Alexandria University Children Hospital and Cairo University Children Hospital from August 2018 to December 2019. Preoperative assessment included cystovaginoscopy and magnetic resonance imaging (MRI) studies with a recording of common channel length and urethral length by each modality. Results There is substantial similarity between MRI and cystoscopy in measuring common channel length; 11 patients had common channel length 1 to 3 cm by cystoscopy. It is the same number by MRI measurement. Nineteen patients had common channel length 3 to 5 cm by cystoscopy and MRI. In total, 16 had urethral length <1.5 cm by MRI, while 14 patients with urethral length <1.5 cm by cystoscopy. However, there is a moderate negative correlation by MRI between common channel length and urethral length, while by cystovaginoscope, there is no significant correlation between common channel length and urethral length. Conclusion Applying MRI or cystoscopy in the preoperative assessment of cloaca cases is equivalent to measuring common channel length, not measuring urethral length. Besides that, the common channel length cannot predict the urethral length.


2014 ◽  
Vol 22 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Fumihide Itokawa ◽  
Terumi Kamisawa ◽  
Toshiaki Nakano ◽  
Takao Itoi ◽  
Yoshinori Hamada ◽  
...  

2009 ◽  
Vol 297 (3) ◽  
pp. G594-G601 ◽  
Author(s):  
Brynn S. Wolff ◽  
Katia Meirelles ◽  
Qinghe Meng ◽  
Ming Pan ◽  
Robert N. Cooney

The metabolic effects of Roux-en-Y gastric bypass (RYGB) are caused by postsurgical changes in gastrointestinal anatomy affecting gut function. Glutamine is a critical gut nutrient implicated in regulating glucose metabolism as a substrate for intestinal gluconeogenesis. The present study examines the effects of obesity and RYGB on intestinal glutamine transport and metabolism. First, lean and obese Zucker rats (ZRs) were compared. Then the effects of RYGB and sham surgery with pair feeding (PF) in obese ZRs were studied. Segments of small intestine (biliopancreatic limb, Roux limb, and common channel) mucosa were harvested and brush border membrane vesicles (BBMVs) were isolated on postoperative day 28. Glutamine transporter activity and abundance, B0AT1 protein, and mRNA levels were measured. Levels of glutaminase, cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C), and glucose-6-phosphatase (G6Pase) were measured to assess glutamine metabolism and intestinal gluconeogenesis. Obesity increased glutamine transport and B0AT1 expression throughout the intestine. RYGB increased glutamine transport activity in the biliopancreatic (3.8-fold) and Roux limbs (1.4-fold) but had no effect on the common channel. The relative abundance of B0AT1 mRNA and protein were increased in the biliopancreatic (6-fold) and Roux limbs (10-fold) after RYGB ( P < 0.05 vs. PF), but not the common channel. Glutaminase levels were increased, whereas the relative abundance of PEPCK-C and G6Pase were decreased in all segments of intestine after RYGB. RYGB selectively increased glutamine absorption in biliopancreatic and Roux limbs by a mechanism involving increased B0AT1 expression. Post-RYGB glutaminase levels were increased, but the reductions in PEPCK-C and G6Pase suggest that RYGB downregulates intestinal gluconeogenesis.


1989 ◽  
Vol 153 (5) ◽  
pp. 969-972 ◽  
Author(s):  
DA Wiedmeyer ◽  
ET Stewart ◽  
WJ Dodds ◽  
JE Geenen ◽  
JA Vennes ◽  
...  

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