scholarly journals Combined versus single treatment regimens for keloid therapy using serial intralesional corticosteroid injections, surgical excision, silicone- and/or cryotherapy.

JPRAS Open ◽  
2021 ◽  
Author(s):  
C Jacobs ◽  
J Wilmink
Keyword(s):  
Surgical Excision ◽  
Single Treatment ◽  
Treatment Regimens ◽  
Intralesional Corticosteroid ◽  
Corticosteroid Injections

scholarly journals What is the role of intralesional corticosteroid injections for keloids before considering surgery?

2015 ◽  
Vol 126 (3) ◽  
pp. 549-550 ◽  
Author(s):  
Louis Insalaco ◽  
Sarah Saxon ◽  
Jeffrey H. Spiegel
Keyword(s):  
Intralesional Corticosteroid ◽  
Corticosteroid Injections

scholarly journals Adjunct Treatment of Recalcitrant Hand Plaques in Nephrogenic Systemic Fibrosis After Imatinib Therapy

2019 ◽  
Vol 3 (6) ◽  
pp. 438-442
Author(s):  
James Foshee ◽  
Thomas Griffin ◽  
Kristin Cam ◽  
Michael Rivlin ◽  
Matthew Keller
Keyword(s):  
Nephrogenic Systemic Fibrosis ◽  
Functional Limitation ◽  
Lower Extremities ◽  
Functional Improvement ◽  
Adjunct Treatment ◽  
Joint Contractures ◽  
Intralesional Corticosteroid ◽  
Initial Improvement ◽  
Effective Adjunct ◽  
Corticosteroid Injections

Nephrogenic systemic fibrosis (NSF) is a sclerotic disorder presenting with painful indurated plaques and skin thickening involving the trunk and extremities, which can lead to tethering and joint contractures.  NSF most commonly affects patients with renal insufficiency who have been exposed to gadolinium. We present a case of NSF involving the bilateral hands, knees, and lower extremities developing over 10 years after gadolinium exposure.  Initial improvement was noted in the lower extremities after initiation of imatinib mesylate therapy, but recalcitrant, thickened hand plaques caused persistent pain and functional limitation. Adjunct intralesional corticosteroid injections produced durable softening of the recalcitrant lesions with considerable functional improvement in hand mobility. Based on our experience, intralesional corticosteroid injections appear to be an effective adjunct treatment in patients with incomplete response to anti-fibrotic therapies.

scholarly journals Outcome of combined surgical and intralesional steroids injection therapy for management of ear keloid

2020 ◽  
Vol 9 (1) ◽  
pp. 43-48
Author(s):  
Amir Bajracharya
Keyword(s):  
Triamcinolone Acetonide ◽  
Corticosteroid Injection ◽  
Surgical Excision ◽  
Good Alternative ◽  
Injection Therapy ◽  
Treatment Modalities ◽  
Aesthetic Outcome ◽  
Intralesional Corticosteroid ◽  
History Of ◽  
The Mean

Background: Ear keloid is one of the challenging problems that affect people of different races with substantial aesthetic outcomes. Various types of treatment modalities, including intralesional corticosteroid injection are advocated to lower recurrence following excision. Objectives: To investigate the efficacy of a combined excision and postoperative intralesional triamcinolone acetonide (TA) injection for treating ear keloid patients. Methodology: This was a descriptive study done to observe the outcome of combined approach of surgical and intra-lesional steroids injection therapy for ear keloids. Age, sex, site, size, duration, recurrence, and aesthetic outcome were evaluated. Results: A total of 18 patients representing 19 ear keloids, with one case having bilateral and 3 pediatric cases were included from February 2018 to January 2019.The mean age was 22 years with female to male ratio of 5:1, site were left sided 9 (50%), right 8 (44%) and 1(6%) bilateral. About 10 (53%) cases were at helix, and 9(47%) at ear lobule. Mean length of ear keloid was 1.53 cm with range of 0.5-3cm and mean breath 1.39cm with the range of 0.5-2.5 cm. The mean duration of ear keloid was 9.47 months. 2 (11%) cases showed a history of recurrence. Injection triamcinolone acetonide hypersensitivity was noted by 1 (5.3%) patient. Evaluation for all patients with aesthetic outcome was mean ± standard deviation (4.38±1.025). Conclusion: Management of ear keloid using the combination of surgical excision and intra-lesional steroids injection therapy can be a good alternative option with low recurrence rate.

scholarly journals Successful Treatment of Kasabach-Merritt Phenomenon With Intralesional Corticosteroid Injections

2012 ◽  
Vol 69 (6) ◽  
pp. 627-632 ◽  
Author(s):  
Jian-Jr Lee ◽  
Li-Ying Lin ◽  
Shun-Wen Hsieh ◽  
Ting-An Chang ◽  
Shiann-Tarng Jou ◽  
...  
Keyword(s):  
Successful Treatment ◽  
Intralesional Corticosteroid ◽  
Corticosteroid Injections

scholarly journals Hidradenitis suppurativa with SAPHO syndrome maintained effectively with adalimumab, methotrexate, and intralesional corticosteroid injections

2018 ◽  
Vol 6 ◽  
pp. 2050313X1877872 ◽  
Author(s):  
Erika L Crowley ◽  
Ashley O’Toole ◽  
Melinda J Gooderham
Keyword(s):  
Hidradenitis Suppurativa ◽  
Relevant Literature ◽  
Skin Inflammation ◽  
Lifestyle Changes ◽  
Definitive Treatment ◽  
Intralesional Corticosteroid ◽  
Treatment Plans ◽  
Bone Inflammation ◽  
Pain Improvement ◽  
Corticosteroid Injections

Introduction: Hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome are chronic, debilitating diseases involving apocrine gland-bearing skin inflammation and bone inflammation, respectively. Although both often present with multiple comorbidities, single patient co-presentation is rare. Methods/Results: This study reports the 8-year treatment course of a 40-year-old man with hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome, and reviews relevant literature. Initial oral and topical antibiotics had little effect. Intralesional corticosteroid injections were effective for localized inflammatory lesions but insufficient for hidradenitis suppurativa control. Adalimumab initiation and local excision of a persistent HS lesion led to stabilization. Adalimumab provided dramatic back pain improvement. Synovitis, acne, pustulosis, hyperostosis, osteitis was diagnosed; adalimumab continuation with subsequent methotrexate addition resulted in hidradenitis suppurativa-synovitis, acne, pustulosis, hyperostosis, osteitis control. Conclusions: Literature regarding comorbid hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome therapy is scarce but growing. Adalimumab, methotrexate, intralesional corticosteroid, and lifestyle changes successfully maintained a severe hidradenitis suppurativa–synovitis, acne, pustulosis, hyperostosis, osteitis–syndrome case. Further studies beyond a case-based review could yield more definitive treatment plans.

Intralesional Corticosteroid Injections for Infantile Hemangiomas of the Eyelid

PEDIATRICS ◽  
1984 ◽  
Vol 74 (2) ◽  
pp. 241-245
Author(s):  
Leonard B. Nelson ◽  
Judith E. Melick ◽  
Robison D. Harley
Keyword(s):  
At Risk ◽  
Intralesional Corticosteroid ◽  
Corticosteroid Injections

Infants with capillary hemangiomas of the eyelid are at risk for amblyopia and strabismus. Several methods of treating these tumors have been associated with complications and limitations. The use of intralesional corticosteroid injections has been demonstrated to be a simple, safe, and effective method of treating capillary hemangiomas of the eyelid.

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