scholarly journals Outcome of combined surgical and intralesional steroids injection therapy for management of ear keloid

2020 ◽  
Vol 9 (1) ◽  
pp. 43-48
Author(s):  
Amir Bajracharya
Keyword(s):  
Triamcinolone Acetonide ◽  
Corticosteroid Injection ◽  
Surgical Excision ◽  
Good Alternative ◽  
Injection Therapy ◽  
Treatment Modalities ◽  
Aesthetic Outcome ◽  
Intralesional Corticosteroid ◽  
History Of ◽  
The Mean

Background: Ear keloid is one of the challenging problems that affect people of different races with substantial aesthetic outcomes. Various types of treatment modalities, including intralesional corticosteroid injection are advocated to lower recurrence following excision. Objectives: To investigate the efficacy of a combined excision and postoperative intralesional triamcinolone acetonide (TA) injection for treating ear keloid patients. Methodology: This was a descriptive study done to observe the outcome of combined approach of surgical and intra-lesional steroids injection therapy for ear keloids. Age, sex, site, size, duration, recurrence, and aesthetic outcome were evaluated. Results: A total of 18 patients representing 19 ear keloids, with one case having bilateral and 3 pediatric cases were included from February 2018 to January 2019.The mean age was 22 years with female to male ratio of 5:1, site were left sided 9 (50%), right 8 (44%) and 1(6%) bilateral. About 10 (53%) cases were at helix, and 9(47%) at ear lobule. Mean length of ear keloid was 1.53 cm with range of 0.5-3cm and mean breath 1.39cm with the range of 0.5-2.5 cm. The mean duration of ear keloid was 9.47 months. 2 (11%) cases showed a history of recurrence. Injection triamcinolone acetonide hypersensitivity was noted by 1 (5.3%) patient. Evaluation for all patients with aesthetic outcome was mean ± standard deviation (4.38±1.025). Conclusion: Management of ear keloid using the combination of surgical excision and intra-lesional steroids injection therapy can be a good alternative option with low recurrence rate.

Outcome of Corticosteroid Injection in De Quervain's Tenosynovitis

2021 ◽  
Vol 15 (11) ◽  
pp. 3288-3292
Author(s):  
Wahid Bakhsh ◽  
Asad Ullah Jan ◽  
Muhammad Shafiq ◽  
Naveed Iqbal ◽  
Muzafar Hussain Buriro ◽  
...  
Keyword(s):  
Pain Score ◽  
Triamcinolone Acetonide ◽  
Corticosteroid Injection ◽  
Mean Value ◽  
Injection Pain ◽  
P Value ◽  
Duration Of Symptoms ◽  
De Quervain’S Tenosynovitis ◽  
Minimum Age ◽  
The Mean

Background: De Quervain's tenosynovitis is a painful and swollen stenosing tenosynovitis of the first dorsal compartment of the wrist. After analysing the patient's medical history and doing a physical examination, a diagnosis is made. Finkelstein's test is almost always positive. Objective: The goal of this study was to investigate the effectiveness of local corticosteroid injections in the treatment of de Quervain's tenosynovitis. Material & Methods: The study enrolled fifty patients with De Querven's Tenosynovitis. NSAIDs were provided orally and topically to all patients for an average of six weeks with no obvious improvement. Using a visual analogue scale, it was determined how much soreness would be felt in the first dorsal compartment and how much pain would be felt during the Finkelstein test. The edoema was removed by injecting a mixture of 1 mL (10 mg) triamcinolone-acetonide and 1 mL of 1% lidocain hydrochloride into the affected wrist's first dorsal compartment. They were subsequently examined every two weeks for twenty-four weeks. After a local triamcinolone acetonide injection, pain and discomfort on the radial side of the wrist were alleviated, and a negative Finkelstein test was done. Results: The mean age among the patients was 36.6 years with 12.4 SD. The maximum age was 60 years and the minimum age was 25 years old. The duration of symptoms in 4-8 weeks was observed, the mean value was 6 weeks with 1.4 as SD the minimum duration recorded was 4 weeks with 8 weeks as maximum duration. At the start of the week of appearance of symptoms the pain score was 6.44 with 1.6 as SD. The minimum pain score was 4 and maximum pain score was 8. Pain score at 4 weeks was 0.66 with 1.6 as SD. As per the independent t-test the p value was less than 0.05 so the test was significant statistically. Conclusion: One or two local steroid injections in the first dorsal compartment can give considerable pain and inflammation alleviation in people with de Quervain's tenosynovitis.

scholarly journals Giant Ocular Surface Squamous Neoplasia Wrapping Almost the Whole Cornea: A Case Report

2020 ◽  
Vol 42 (2) ◽  
pp. 94-96
Author(s):  
Poonam Shrestha ◽  
Mukesh Pandey
Keyword(s):  
Ocular Surface ◽  
Histopathological Examination ◽  
Promising Result ◽  
Intraepithelial Neoplasia ◽  
Surgical Excision ◽  
Treatment Modalities ◽  
Ocular Surface Squamous Neoplasia ◽  
History Of ◽  
Grade 3 ◽  
Clinical Pictures

Ocular surface squamous neoplasia (OSSN) includes the dysplastic lesions involving the epithelium of conjunctiva and cornea with various clinical pictures. Histopathological examination of the excised tissue is the benchmark for diagnosis. Surgery, chemotherapy, immunotherapy are the various treatment modalities which in combination shows promising result. We present here a case of 83 years old female patient with history of fleshy mass covering the cornea and the patient was diagnosed clinically as ocular surface squamous neoplasia. Patient underwent surgical excision of the mass followed by cryotherapy. Histopathological examination revealed conjunctival intraepithelial neoplasia of grade 3. Six months after treatment the patient is completely tumor free with no recurrence.

Surgical management of an odontogenic cutaneous fistula

2021 ◽  
Vol 14 (3) ◽  
pp. e240306
Author(s):  
Mairéad Sarah Kelly ◽  
Dylan J Murray
Keyword(s):  
Surgical Management ◽  
Surgical Excision ◽  
Treatment Modalities ◽  
Initial Assessment ◽  
Purulent Discharge ◽  
Left Cheek ◽  
Cutaneous Fistula ◽  
Source Of Infection ◽  
General Dental Practitioner ◽  
History Of

A patient presented to our unit with a long history of a discharging skin infection on his left cheek, which came and went. He had been seen by numerous healthcare practitioners including his general practitioner, general dental practitioner and dermatologist, with no resolution. He was eventually diagnosed with an odontogenic cutaneous fistula (OCF), for which he underwent surgical management. The purpose of the study is to describe the diagnosis and surgical management of an OCF, from initial assessment through to postoperative review and discharge. Following surgical management of the OCF and treatment of the source of infection by dental extraction, the patient is no longer experiencing purulent discharge through his left cheek. The extraoral skin site of drainage at his left cheek has resolved completely, with minimal residual scarring. OCF can be managed by a number of different treatment modalities. The treatment of an OCF by surgical excision is presented.

Our experience with intralesional corticosteroid injection therapy for infantile adnexal hemangiomao

Orbit ◽  
1985 ◽  
Vol 4 (3) ◽  
pp. 177-181 ◽  
Author(s):  
G. Bonavolont ◽  
P. Vassallo ◽  
G. Uccello ◽  
F. Tranfa
Keyword(s):  
Corticosteroid Injection ◽  
Injection Therapy ◽  
Intralesional Corticosteroid

scholarly journals Can pleural packing be an effective solution for uncontrollable intra or post-operative hemorrhage

2020 ◽  
Vol 7 (7) ◽  
pp. 2087
Author(s):  
Hazem Zribi ◽  
Abderrahmen Ammar ◽  
Amina Abdelkbir ◽  
Imen Bouacida ◽  
Sarra Maazaoui ◽  
...  
Keyword(s):  
Thoracic Surgery ◽  
Invasive Pulmonary Aspergillosis ◽  
Case Series ◽  
Good Alternative ◽  
Common Point ◽  
Retrospective Case ◽  
Case Series Study ◽  
History Of ◽  
The Common ◽  
The Mean

Background: Uncontrollable bleeding during thoracic surgery has been a challenging problem faced by surgeons. The aim of this study was to clarify the usefulness of pleural packing as a good alternative to control hemorrhage and to deduce the common point between those patients.Methods: This was a retrospective case series study of eight patients who underwent thoracic surgery with uncontrollable intrathoracic haemorrhage and shock which required intrathoracic packing from January 2014 to December 2019.Results: During the study period, eight patients underwent thoracic surgery with uncontrollable intrathoracic haemorrhage and needed packing.  Successful hemostasis was achieved in all cases after pleural packing. The mean age was 58.5 years and six patients were males. The common point was the history of pulmonary tuberculosis which was with invasive pulmonary aspergillosis for two patients. Incision was a posterolateral thoracotomy in all cases and six patients required pulmonary resection (five lobectomy and one bilobectomy), one patient required decortication, and one had tumorectomy of a paragonglioma located in the Barety’s space. The unpacking took place right after 48 hours. An arrest of the bleeding was noticed in all the remaining patients. The mean time of the mechanical ventilation was 11 days. Complications included atelectasis and infectious pneumonitis. We noted one case of death.Conclusions: Intrathoracic packing may be an effective and feasible technique in managing uncontrollable post-operative hemorrhage when the life of patients is in danger. This technique should always be considered for patients with tuberculosis history.

scholarly journals The Efficacy of Local Application of Mitomycin C in Reducing Recurrence Rate of Keloid after Surgery

2016 ◽  
Vol 24 (3) ◽  
pp. 117-121
Author(s):  
Anindita Sengupta ◽  
Arindam Das ◽  
Debasish Ghosh ◽  
Subhadip Dhara ◽  
Soumyendu Ghosh ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Mitomycin C ◽  
Topical Application ◽  
Previous History ◽  
Surgical Excision ◽  
Recurrence Rates ◽  
History Of ◽  
Study Population ◽  
Group 2 ◽  
Group 1

Introduction  Keloid is a hyperproliferative response of the fibroelastic connective tissue to dermal trauma, appearing predominantly in areas of high skin tension. Surgical excision produces immediate cosmetic correction, but recurrence rates after surgical treatment alone are high and post excision adjunct therapies should be considered. Topical application of Mitomycin C has shown to suppress cell division, fibroblast proliferation, protein and collagen synthesis and angiogenesis. In our study we applied it locally after surgical excision of keloid of auricle and compared the outcome with post-surgical perilesional Triamcinolone acetonide injection to reduce recurrence. Materials and Method Fifty cases with primary or recurrent keloid over auricle were studied from February 2015 to January 2016. They are divided into two groups; Group 1 received local Mitomycin C application after keloid excision while Group 2 had perilesional injection of Triamcinolone acetonide after surgical excision of keloid. The results were compared 6 months after the initial treatment. Result  There was no statistical difference in the baseline characteristics like age, sex, type of symptoms and previous history of recurrence between the two groups. Most of the patients in both the groups were aged between 14 and 30 years. The study population constituted predominantly of females. At the end of 6 months follow up, the recurrences noted were 5 and 6 respectively in Group 1 and 2 out of 25 patients in each group. Conclusion After surgical excision of keloid, topical application of Mitomycin C is as effective as intralesional Triamcinolone acetonide injection in terms of recurrence of the keloids affecting the auricle.

scholarly journals Retrospective Evaluation of Chronic Idiopathic Thrombocytopenia in Libyan Children

2021 ◽  
pp. 13-21
Author(s):  
Haloom Abdel Salam Elhashmi ◽  
Ainour Ibrahim Abdulhamid
Keyword(s):  
Platelet Count ◽  
Laboratory Data ◽  
Complete Response ◽  
Response To Therapy ◽  
Treatment Modalities ◽  
Female Ratio ◽  
Idiopathic Thrombocytopenia ◽  
Chronic Itp ◽  
History Of ◽  
The Mean

Immune thrombocytopenic purpura (ITP) is the most common cause of acquired thrombocytopenia in children. Approximately 10-20% of children with Immune thrombocytopenia (ITP) suffer from a chronic clinical disease that requires follow up and medical intervention according to the severity of bleeding manifestation. Aims: To evaluate the demographic, clinical, and laboratory features, treatment modalities, and response to therapy in Libyan children with chronic idiopathic thrombocytopenia. Methods: A retrospective study was conducted at the hematology clinic of the pediatric department, Benghazi medical center, and Benghazi Children Hospital. The duration of the study was from January 1998 to December 2018. comprised of demographics, clinical, laboratory data, therapy and therapy response in Libyan chronic ITP. Results: In our study, the mean age of chronic ITP patients was 4.9 years, slightly higher in male patients 43 (52.4%) With a male/female ratio 1.1:1. The most frequent symptoms were mild   which were limited to bruises and petechiae on the skin. (57.3%). The preceding history of viral infection was uncommon in patients with chronic ITP (22%) while the past history of MMR vaccination is quite rare and constituted only (2%). The mean platelet count before treatment (i.e. at presentation) was (22.7x109/L) while mean platelet count after treatment (213.6 x109/L. Treatment consisted of combined Steroid + IVIG in 27 (77.1% response), steroids in 23 (73.9% response), intravenous immunoglobulin (IVIG) in 11 (90.9% response), and no therapy in 21 (95.2% response).Complete response was achieved in 82.9% % showed a complete response either spontaneous or following the treatment. No patient was presented with intracranial hemorrhage. Conclusions: Chronic ITP in Libyan children had a benign nature, none of our patients developed severe symptoms as life-threatening bleeding like CNS bleeding or died, IVIG give more optimistic response as compare to steroid. And the majority of children with chronic ITP in this study achieved remission.

scholarly journals Combined Surgical Treatment of Gynecomastia

2015 ◽  
Vol 42 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Y. Yordanov ◽  
J. M. Lasso ◽  
A. Shef
Keyword(s):  
Surgical Treatment ◽  
Surgical Excision ◽  
Aesthetic Outcome ◽  
Reliable Technique ◽  
Good Balance ◽  
Breast Enlargement ◽  
Areola Complex ◽  
Skin Excess ◽  
The Mean

Summary Surgical treatment of gynecomastia could present unique challenges for the plastic surgeon. Achieving a good balance between effectiveness of the selected approach and the satisfactory aesthetic outcome often is a difficult endeavor. Optimal surgical treatment involves a combination of liposuction and direct excision. In the present study the charts of 11 patients treated with suction-assisted liposuction and direct surgical excision were retrospectively reviewed; a special emphasis is placed on the surgical technique. The mean follow-up period of the patients was 11.6 months. No infection, hematoma, nipple-areola complex necrosis and nipple retraction was encountered in this series. The combined surgical treatment of gynecomastia has shown to be a reliable technique in both small and moderate breast enlargement including those with skin excess.

scholarly journals Oral Mucocele: Various treatment modalities

2018 ◽  
Vol 7 (3) ◽  
pp. 110-113
Author(s):  
Sapna Agrawal ◽  
Bandana Koirala ◽  
Mamta Dali ◽  
Sneha Shrestha
Keyword(s):  
Treatment Modalities ◽  
Surgical Removal ◽  
Intralesional Injection ◽  
Complete Regression ◽  
Minor Salivary Glands ◽  
Lower Lip ◽  
Case Selection ◽  
Intralesional Corticosteroid ◽  
History Of ◽  
Rapid Appearance

Mucoceles are common lesions of the oral cavity that result from an alteration in the minor salivary glands due to mucus accumulation and are broadly classified into extravasation and retention types. Rapid appearance, specific location, history of trauma, bluish color, and consistency help in the diagnosis. There are various treatment modalities which include conventional surgical removal, laser ablation, cryosurgery, sclerotherapy, micro-marsupialization, and intralesional injection of sclerosing agent or corticosteroid. Intralesional corticosteroid therapy and micro-marsupialization, though widely accepted treatment choices, the complete regression may not always be assured holding the importance of case selection and regular follow-ups for timely recognition of recurrences. This report highlights on the management of mucocele of lower lip in a 12-year-old female treated with different modalities: intralesional injection of corticosteroid, micro- marsupialization and surgical approach.

scholarly journals Successful Treatment of Intralesional Triamcilonon Acetonide Injection in Keloid Patients

2019 ◽  
Vol 7 (2) ◽  
pp. 275-278
Author(s):  
Nghi Dinh Huu ◽  
Sau Nguyen Huu ◽  
Xuan Le Thi ◽  
Thuong Nguyen Van ◽  
Phuong Pham Thi Minh ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Successful Treatment ◽  
Corticosteroid Injection ◽  
Control Group ◽  
National Hospital ◽  
Menstrual Cycles ◽  
Intralesional Corticosteroid ◽  
Excellent Improvement

AIM: Evaluation the effect of intralesional corticosteroid injection on keloid, at the National Hospital of Dermatology and Venereology from 1/2009 to 12/2009. METHODS: A group of 65 patients with keloid were randomly assigned into three groups. In the studied group, 33 patients were intralesionally injected 7.5 mg/1 cm2 of TCA. In the control group, TAC 32 patients were intralesionally injected 15 mg/1 cm2 of TCA. The result was evaluated basing on the criteria of Henderson (1998) and El-Tonsy (1996). RESULTS: In comparison between 2 groups, good to excellent improvement in the studied group was statistically higher than the control group (90.7% versus 68.7%; p < 0.05). After each injection, the thickness of the scar was reduced 1.24 ± 0.53 mm in the studied group and 0.81 ± 0.39 mm in the control group. The disappearance of pain and itching after treatment were 86.6% and 95.5% in the studied group and 78.1% and 80% in the control group (p > 0.05). Ulceration, acne and troublesome with menstrual cycles were sometimes were noted more frequently in the control group than in the studied group. CONCLUSION: Intralesional triamcinolone acetonide injection had a good result, and 7.5 mg/1 cm2 scar is the best dose for treatment of keloid.

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