Regional characteristics of cortical bone quality in the proximal humerus of postmenopausal women: a preliminary study

2019 ◽  
Vol 28 (4) ◽  
pp. 685-691
Author(s):  
Yeming Wang ◽  
Jian Li ◽  
Jianhua Yang ◽  
Jingming Dong
Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 570
Author(s):  
Masayoshi Yamada ◽  
Chongxiao Chen ◽  
Toshie Sugiyama ◽  
Woo Kyun Kim

Changes in medullary and cortical bone structure with age remain unclear. Twenty Hy-Line W36 hens, 25 or 52 weeks of age, were euthanized, and both tibiae were collected when an egg was present in the magnum. Serial cross sections of the tibiae were stained with Alcian blue. The bones were scanned using micro-computed tomography. Trabecular width (Tb.Wi) was significantly higher (p < 0.05) in 25-week-old hens, whereas medullary bone tissue volume (TV) was significantly higher (p < 0.01) in 52-week-old hens. 25-week-old hens had significantly higher (p < 0.01) bone volume fraction (BVF = calcified tissue / TV). Moreover, the cortical bone parameters were significantly higher (TV and bone mineral content (BMC) at p < 0.05, and bone volume (BV) and BVF at p < 0.01) in younger hens. Open porosity and total porosity, which indicate less density, were significantly higher (p < 0.01) in older hens. Older hens showed significantly higher (p < 0.01) tibial diaphysis TV than younger hens. Younger hens had significantly higher (p < 0.01) BV, BVF and bone mineral density (BMD) of the tibial diaphysis. These findings reveal that reductions in medullary bone quality might be associated with age-related low estrogen levels and stimulation of osteoclastic bone resorption by parathyroid hormone. Cortical bone quality decreased with enlargement of the Haversian canals and loss of volume, with a longer egg-laying period leading to osteoporosis.


2006 ◽  
Vol 126 (2) ◽  
pp. 93-100 ◽  
Author(s):  
Gerd Diederichs ◽  
Jan Korner ◽  
Jörg Goldhahn ◽  
Berend Linke

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S372-S373
Author(s):  
K.K. Nishiyama ◽  
H.M. Macdonald ◽  
H.R. Buie ◽  
D.A. Hanley⁎ ◽  
S.K. Boyd

2020 ◽  
Vol 54 (S2) ◽  
pp. 307-315
Author(s):  
Sonali Jain ◽  
Sumit Arora ◽  
Swati Gupta ◽  
Siddharth Sharma ◽  
Nitish Bansal ◽  
...  

2019 ◽  
Vol 101-B (10) ◽  
pp. 1307-1312
Author(s):  
Matthijs Jacxsens ◽  
Jeremias Schmid ◽  
Vilijam Zdravkovic ◽  
Bernhard Jost ◽  
Christian Spross

Aims In order to determine whether and for whom serial radiological evaluation is necessary in one-part proximal humerus fractures, we set out to describe the clinical history and predictors of secondary displacement in patients sustaining these injuries. Patients and Methods Between January 2014 and April 2016, all patients with an isolated, nonoperatively treated one-part proximal humerus fracture were prospectively followed up. Clinical and radiological evaluation took place at less than two, six, 12, and 52 weeks. Fracture configuration, bone quality, and comminution were determined on the initial radiographs. Fracture healing, secondary displacement, and treatment changes were recorded during follow-up. Results In 100 patients (59 female, 41 male; mean age 57 years), 91 of the fractures (91%) remained stable. In five of nine patients (55%) with secondary displacement, surgery was recommended. Comminution, present in 23 patients (23%), was identified as a predictor of secondary displacement (p < 0.001). Patients’ age, sex, fracture configuration, and bone quality were not associated with secondary displacement (p ≥ 0.438). Nonoperative treatment resulted in a mean absolute Constant score (CS) of 80 (49 to 98), relative CS of 101% (63% to 138%), median subjective shoulder value of 95% (interquartile range (IQR) 90% to 100%), and median EuroQol five-dimensional questionnaire score of 0.89 (IQR 0.80 to 1.00) with bone union in all cases at one-year follow-up. Conclusion Radiological re-evaluation was only necessary in patients presenting with comminution and may be redundant for 77% of patients with one-part proximal humerus fractures. Nonoperative treatment of one-part proximal humerus fractures remains the mainstay of treatment with a low rate of secondary surgery, a high union rate, and good clinical results. Cite this article: Bone Joint J 2019;101-B:1307–1312


2019 ◽  
Vol 10 (10) ◽  
pp. 6556-6567 ◽  
Author(s):  
Haiming Jin ◽  
Zhenxuan Shao ◽  
Qingqing Wang ◽  
Jiansen Miao ◽  
Xueqin Bai ◽  
...  

Postmenopausal osteoporosis (PMO) is a progressive disease occurring in elderly postmenopausal women that is characterized by low bone mass and impaired bone quality.


1995 ◽  
Vol 15 (3) ◽  
pp. 124-128 ◽  
Author(s):  
E. Lea Watson ◽  
R.V. Katz ◽  
R. Adelezzi ◽  
Helen C. Gift ◽  
S.M. Dunn

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