scholarly journals Anastatica hierochuntica (L.) methanolic and aqueous extracts exert antiproliferative effects through the induction of apoptosis in MCF-7 breast cancer cells

2020 ◽  
Vol 28 (8) ◽  
pp. 985-993
Author(s):  
Saranya Rameshbabu ◽  
Safia A. Messaoudi ◽  
Zeyad Ibrahim Alehaideb ◽  
Mohammed Syed Ali ◽  
Anuradha Venktraman ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Aqueous Extracts ◽  
Antiproliferative Effects ◽  
Induction Of Apoptosis ◽  
Mcf 7

scholarly journals Roles of p53 and Caspases in Induction of Apoptosis in MCF-7 Breast Cancer Cells Treated with a Methanolic Extract of Nigella Sativa Seeds

2014 ◽  
Vol 15 (22) ◽  
pp. 9655-9660 ◽  
Author(s):  
Mohammed I. Alhazmi ◽  
Tarique N. Hasan ◽  
Gowhar Shafi ◽  
Abdullah H. Al-Assaf ◽  
Mohammed A. Alfawaz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Methanolic Extract ◽  
Nigella Sativa ◽  
Induction Of Apoptosis ◽  
Mcf 7

scholarly journals gef Gene Expression in MCF-7 Breast Cancer Cells is Associated with a Better Prognosis and Induction of Apoptosis by p53-Mediated Signaling Pathway

2011 ◽  
Vol 12 (11) ◽  
pp. 7445-7458 ◽  
Author(s):  
Houria Boulaiz ◽  
Pablo J. Álvarez ◽  
Jose Prados ◽  
Juan Marchal ◽  
Consolación Melguizo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Cancer Cells ◽  
Signaling Pathway ◽  
Breast Cancer Cells ◽  
Induction Of Apoptosis ◽  
Mcf 7

scholarly journals Induction of apoptosis in MCF-7 human breast cancer cells by Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelium)

2015 ◽  
Vol 13 (2) ◽  
pp. 1243-1249 ◽  
Author(s):  
TAE HWAN KIM ◽  
JU SUNG KIM ◽  
ZOO HAYE KIM ◽  
REN BIN HUANG ◽  
YOUNG LYE CHAE ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Ganoderma Lucidum ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Polyporus Umbellatus ◽  
Induction Of Apoptosis ◽  
Mcf 7

Growth Inhibition and Induction of Apoptosis in MCF-7 Breast Cancer Cells by Fermented Soy Milk

2002 ◽  
Vol 43 (2) ◽  
pp. 214-226 ◽  
Author(s):  
Wen-Huei Chang ◽  
Jun-Jen Liu ◽  
Ching-Hsein Chen ◽  
Tien-Shang Huang ◽  
Fung-Jou Lu
Keyword(s):  
Breast Cancer ◽  
Growth Inhibition ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Soy Milk ◽  
Induction Of Apoptosis ◽  
Mcf 7

scholarly journals Analogs of GnRH-I and GnRH-II inhibit epidermal growth factor-induced signal transduction and resensitize resistant human breast cancer cells to 4OH-tamoxifen

2005 ◽  
Vol 153 (4) ◽  
pp. 613-625 ◽  
Author(s):  
Andreas R Günthert ◽  
Carsten Gründker ◽  
Agnes Olota ◽  
Julia Läsche ◽  
Nicola Eicke ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Antiproliferative Effects ◽  
Epidermal Growth ◽  
Mcf 7

About 50–64% of human breast cancers express receptors for GnRH-I. Direct antiproliferative effects of analogs of GnRH-I on human breast cancer cell lines have been shown. They are at least in part mediated by antagonizing growth promoting effects of estradiol, epidermal growth factor (EGF) or insulin-like growth factor. Recently, expression of a putative receptor for GnRH-II in human tissues was demonstrated. Antiproliferative effects of GnRH-II in human endometrial and ovarian cancer cells were shown not to be mediated through the GnRH-I receptor. Now we demonstrate direct anti-proliferative effects of the GnRH-I analog Triptorelin and the GnRH-II analog [d-Lys6]GnRH-II in MCF-7 and T47D human breast cancer cells expressing GnRH-I receptors and putative GnRH-II receptors. Pretreatment with Triptorelin or [d-Lys6]GnRH-II blocked EGF-induced autophosphoryla-tion of EGF receptor and activation of mitogen-activated protein kinase (extracellular-signal-regulated kinase 1/2 (ERK1/2)) in these cells. In sublines of MCF-7 and T47D cells, which were developed to be resistant to 4OH-tamoxifen, HER-2/p185 was overexpressed. Pretreatment of these cell lines with Triptorelin or [d-Lys6]GnRH-II completely abolished resistance to 4OH-tamoxifen, assessed by 4OH-tamoxifen-induced apoptosis. Analogs of GnRH-I and GnRH-II counteract EGF-dependent signal transduction in human breast cancer cells with expression of receptors for GnRH-I and GnRH-II. Through this mechanism, they probably reverse acquired resistance to 4OH-tamoxifen mediated through overexpression or activation of receptors of the c-erbB family.

Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata

2006 ◽  
Vol 231 (2) ◽  
pp. 215-227 ◽  
Author(s):  
Hsin-Ling Yang ◽  
Chee-Shan Chen ◽  
Wen-Huei Chang ◽  
Fung-Jou Lu ◽  
Yu-Ching Lai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Growth Inhibition ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Antrodia Camphorata ◽  
Induction Of Apoptosis ◽  
Mcf 7

Induction of apoptosis in MCF-7 human breast cancer cells by phytochemicals fromAnoectochilus formosanus

2004 ◽  
Vol 11 (6) ◽  
pp. 928-939
Author(s):  
Lie-Fen Shyur ◽  
Chih-Huai Chen ◽  
Chiu-Ping Lo ◽  
Sheng-Yang Wang ◽  
Pei-Ling Kang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Induction Of Apoptosis ◽  
Mcf 7
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