scholarly journals Force recovery and axonal regeneration of the sternomastoid muscle reinnervated with the end-to-end nerve anastomosis

2013 ◽  
Vol 182 (2) ◽  
pp. e51-e59 ◽  
Author(s):  
Stanislaw Sobotka ◽  
Liancai Mu
Keyword(s):  
Axonal Regeneration ◽  
Sternomastoid Muscle ◽  
Nerve Anastomosis ◽  
Force Recovery ◽  
End To End

scholarly journals End-to-side nerve repair using fibrin glue in rats

2010 ◽  
Vol 25 (2) ◽  
pp. 158-162 ◽  
Author(s):  
Daniel Nunes e Silva ◽  
Julice Coelho ◽  
Fabrício de Oliveira Frazílio ◽  
Alexandre Nakao Odashiro ◽  
Paulo de Tarso Camillo de Carvalho ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Axonal Regeneration ◽  
Nerve Repair ◽  
Control Group ◽  
Morphometrical Analysis ◽  
Walking Pattern ◽  
Group A ◽  
Nerve Anastomosis ◽  
Group B ◽  
Control Group Group

PURPOSE: To evaluate axonal regeneration after end-to-side nerve repair with fibrin glue in rats. METHODS: Forty-five Wistar rats were divided into three groups: group A (n=15), were not submitted to surgery (control group); group B (n=15) were submitted to fibular transection without repair; and group C (n=15), were submitted to fibular transection with end-to-side nerve anastomosis using fibrin glue, in the lateral surface of an intact tibial nerve. The three groups were submitted to walking track (30 and 90 days) and posterior morphometrical analysis (90 days). RESULTS: The functional tests demonstrated that there was no difference in the walking track during the study in group A (p>0.05). The group B had walking pattern impairment in the two tests (p>0.05). The group C had walking pattern impairment in the first test, with important recovery in the second test (p<0.05). The morphometrical assessment revealed significantly higher number of regenerated mielinates axons in group C, compared to group B (p<0.05). CONCLUSION: The end-to-side nerve repair with fibrin glue shows axonal recovery, demonstrated through functional and morphometrical ways in rats.

scholarly journals Morphometric and Functional Analysis of Axonal Regeneration after End-to-end and End-to-side Neurorrhaphy in Rats

2015 ◽  
Vol 3 (3) ◽  
pp. e326 ◽  
Author(s):  
Carlos Eduardo Fagotti de Almeida ◽  
Jayme Adriano Farina Junior ◽  
Benedicto Oscar Colli
Keyword(s):  
Functional Analysis ◽  
Axonal Regeneration ◽  
End To End

Oculomotor Nerve Anastomosis

Neurosurgery ◽  
1982 ◽  
Vol 10 (4) ◽  
pp. 490-491 ◽  
Author(s):  
Takashi Iwabuchi ◽  
Mikio Suzuki ◽  
Tsutomu Nakaoka ◽  
Shigeharu Suzuki
Keyword(s):  
Pituitary Adenoma ◽  
Action Potential ◽  
Clinical Signs ◽  
Oculomotor Nerve ◽  
Neural Regeneration ◽  
Levator Palpebrae ◽  
Levator Palpebrae Superioris Muscle ◽  
Nerve Anastomosis ◽  
Aberrant Regeneration ◽  
End To End

Abstract We report a patient who underwent anastomosis of the left oculomotor nerve, which had been inadvertently and bluntly severed during the resection of a left parasellar chromophobe pituitary adenoma. Neural regeneration was confirmed by the reappearance of voluntary adduction of the eyeball, clinical signs of aberrant regeneration, and the appearance of an action potential on electromyography of the levator palpebrae superioris muscle 1 year after end-to-end anastomosis of the nerve.

scholarly journals Hypoglossal Facial Nerve Anastomosis for Post-Operative and Post-Traumatic Complete Facial Nerve Paralysis

2019 ◽  
Vol 7 (23) ◽  
pp. 3984-3996
Author(s):  
Amr Abdelmonam Abdelaziz M. Elkatatny ◽  
Hany Abdelrahim Abdelrazik Abdallah ◽  
Dina Ghoraba ◽  
Tarek Ahmed Amer ◽  
Tarek Hamdy
Keyword(s):  
Facial Nerve ◽  
Facial Paralysis ◽  
Cerebellopontine Angle ◽  
Bone Fractures ◽  
Petrous Bone ◽  
Facial Nerve Paralysis ◽  
Nerve Paralysis ◽  
Facial Reanimation ◽  
Nerve Anastomosis ◽  
End To End

AIM: This study aims to evaluate the outcome of patients with complete facial paralysis following surgery to cerebellopontine angle tumours or following traumatic petrous bone fractures after reanimation by hypoglossal-facial anastomosis as regards clinical improvement of facial asymmetry and facial muscle contractility as well as complications associated with hypoglossal-facial reanimation procedure. METHODS: This thesis included a prospective study to be carried out on 15 patients with unilateral complete lower motor neuron facial paralysis (11 patients after cerebellopontine angle tumour resection and 4 patients after traumatic transverse petrous bone fracture) operated upon by end to end hypoglossal-facial nerve anastomosis in Cairo university hospitals in the period between June 2015 and January 2017. RESULTS: At one year follow up the improvement of facial nerve functions were as follows: Three cases (20%) had improved to House Hrackmann grade II, eleven cases (73.33%) had improved to grade III, and one patient (6.66%) had improved to House Brackmann grade IV. CONCLUSION: Despite the various techniques in facial reanimation following facial nerve paralysis, the end to end hypoglossal-facial nerve anastomosis remains the gold standard procedure with satisfying results in cases of the viable distal facial stump and non-atrophic muscles. Early hypoglossal-facial anastomotic repair after acute facial nerve injury is associated with better long-term facial function outcomes and should be considered in the management algorithm.

scholarly journals Long-Standing Motor and Sensory Recovery following Acute Fibrin Sealant Based Neonatal Sciatic Nerve Repair

2016 ◽  
Vol 2016 ◽  
pp. 1-19 ◽  
Author(s):  
Natalia Perussi Biscola ◽  
Luciana Politti Cartarozzi ◽  
Rui Seabra Ferreira Junior ◽  
Benedito Barraviera ◽  
Alexandre Leite Rodrigues de Oliveira
Keyword(s):  
Sciatic Nerve ◽  
Fibrin Sealant ◽  
Axonal Regeneration ◽  
Neuronal Survival ◽  
Nerve Repair ◽  
Sensory Function ◽  
Ultrastructural Changes ◽  
Sensory Recovery ◽  
End To End ◽  
Plexus Lesion

Brachial plexus lesion results in loss of motor and sensory function, being more harmful in the neonate. Therefore, this study evaluated neuroprotection and regeneration after neonatal peripheral nerve coaptation with fibrin sealant. Thus, P2 neonatal Lewis rats were divided into three groups: AX: sciatic nerve axotomy (SNA) without treatment; AX+FS: SNA followed by end-to-end coaptation with fibrin sealant derived from snake venom; AX+CFS: SNA followed by end-to-end coaptation with commercial fibrin sealant. Results were analyzed 4, 8, and 12 weeks after lesion. Astrogliosis, microglial reaction, and synapse preservation were evaluated by immunohistochemistry. Neuronal survival, axonal regeneration, and ultrastructural changes at ventral spinal cord were also investigated. Sensory-motor recovery was behaviorally studied. Coaptation preserved synaptic covering on lesioned motoneurons and led to neuronal survival. Reactive gliosis and microglial reaction decreased in the same groups (AX+FS, AX+CFS) at 4 weeks. Regarding axonal regeneration, coaptation allowed recovery of greater number of myelinated fibers, with improved morphometric parameters. Preservation of inhibitory synaptic terminals was accompanied by significant improvement in the motor as well as in the nociceptive recovery. Overall, the present data suggest that acute repair of neonatal peripheral nerves with fibrin sealant results in neuroprotection and regeneration of motor and sensory axons.

scholarly journals End-to-end hypoglossal-facial nerve anastomosis - surgical video

2021 ◽  
Vol 1 ◽  
pp. 100767
Author(s):  
A. Ferreira ◽  
V. Carvalho ◽  
R. Vaz ◽  
A. Vilarinho
Keyword(s):  
Facial Nerve ◽  
Surgical Video ◽  
Nerve Anastomosis ◽  
End To End ◽  
Anastomosis Surgical

scholarly journals Electromyography as an intraoperative test to assess the quality of nerve anastomosis – experimental study on rats

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 556-562
Author(s):  
Norbert Czapla ◽  
Piotr Bargiel ◽  
Jan Petriczko ◽  
Daniel Kotrych ◽  
Piotr Krajewski ◽  
...  
Keyword(s):  
Nerve Conduction ◽  
Proximal Part ◽  
Assessment Method ◽  
Nerve Reconstruction ◽  
Nerve Anastomosis ◽  
End To End ◽  
Correct Technique ◽  
The Right ◽  
Intraoperative Test

AbstractBackgroundMany factors contribute to successful nerve reconstruction. The correct technique of anastomosis is one of the key elements that determine the final result of a surgery. The aim of this study is to examine how useful an electromyography (EMG) can be as an objective intraoperative anastomosis assessment method.MethodsThe study material included 12 rats. Before the surgery, the function of the sciatic nerve was tested using hind paw prints. Then, both nerves were cut. The left nerve was sutured side-to-side, and the right nerve was sutured end-to-end. Intraoperative electromyography was performed. After 4 weeks, the rats were reassessed using the hind paw print analysis and electromyography.ResultsAn analysis of left and right hind paw prints did not reveal any significant differences between the length of the steps, the spread of the digits in the paws, or the deviation of a paw. The width of the steps also did not change.Electromyography revealed that immediately after a nerve anastomosis (as well as 4 weeks after the surgery), better nerve conduction was observed through an end-to-end anastomosis. Four weeks after the surgery, better nerve conduction was seen distally to the end-to-end anastomosis.ConclusionsThe results indicate that in acute nerve injuries intraoperative electromyography may be useful to obtain unbiased information on whether the nerve anastomosis has been performed correctly – for example, in limb replantation.When assessing a nerve during a procedure, EMG should be first performed distally to the anastomosis (the part of the nerve leading to muscle fibers) and then proximally to the anastomosis (the proximal part of the nerve). Similar EMG results can be interpreted as a correct nerve anastomosis.The function of the distal part of the nerve and the muscle remains intact if the neuromuscular transmission is sustained.

Surgical management of extracranial carotid artery aneurysms

VASA ◽  
2016 ◽  
Vol 45 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Jan Paweł Skóra ◽  
Jacek Kurcz ◽  
Krzysztof Korta ◽  
Przemysław Szyber ◽  
Tadeusz Andrzej Dorobisz ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Surgical Management ◽  
Minor Stroke ◽  
Stroke Rate ◽  
Extracranial Carotid Artery ◽  
Long Term Follow Up ◽  
End To End ◽  
Dacron Patch ◽  
Major Stroke

Abstract. Background: We present the methods and results of the surgical management of extracranial carotid artery aneurysms (ECCA). Postoperative complications including early and late neurological events were analysed. Correlation between reconstruction techniques and morphology of ECCA was assessed in this retrospective study. Patients and methods: In total, 32 reconstructions of ECCA were performed in 31 symptomatic patients with a mean age of 59.2 (range 33 - 84) years. The causes of ECCA were divided among atherosclerosis (n = 25; 78.1 %), previous carotid endarterectomy with Dacron patch (n = 4; 12.5 %), iatrogenic injury (n = 2; 6.3 %) and infection (n = 1; 3.1 %). In 23 cases, intervention consisted of carotid bypass. Aneurysmectomy with end-to-end suture was performed in 4 cases. Aneurysmal resection with patching was done in 2 cases and aneurysmorrhaphy without patching in another 2 cases. In 1 case, ligature of the internal carotid artery (ICA) was required. Results: Technical success defined as the preservation of ICA patency was achieved in 31 cases (96.9 %). There was one perioperative death due to major stroke (3.1 %). Two cases of minor stroke occurred in the 30-day observation period (6.3 %). Three patients had a transient hypoglossal nerve palsy that subsided spontaneously (9.4 %). At a mean long-term follow-up of 68 months, there were no major or minor ipsilateral strokes or surgery-related deaths reported. In all 30 surviving patients (96.9 %), long-term clinical outcomes were free from ipsilateral neurological symptoms. Conclusions: Open surgery is a relatively safe method in the therapy of ECCA. Surgical repair of ECCAs can be associated with an acceptable major stroke rate and moderate minor stroke rate. Complication-free long-term outcomes can be achieved in as many as 96.9 % of patients. Aneurysmectomy with end-to-end anastomosis or bypass surgery can be implemented during open repair of ECCA.

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