Risk Factor and Etiology Analysis of Ischemic Stroke in Young Adult Patients

2014 ◽  
Vol 23 (3) ◽  
pp. e221-e227 ◽  
Author(s):  
Rosaria Renna ◽  
Fabio Pilato ◽  
Paolo Profice ◽  
Giacomo Della Marca ◽  
Aldobrando Broccolini ◽  
...  
2015 ◽  
Vol 16 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Imran Imran ◽  
Rusdi Lamsudin ◽  
Ponpon Idjradinata ◽  
Tri Hanggono Achmad ◽  
Amelani Maskoen ◽  
...  

2018 ◽  
Vol 61 ◽  
pp. e210
Author(s):  
H. Tavares ◽  
D. Amaral ◽  
H. Amorim ◽  
P. Lopes ◽  
M.J. Festas ◽  
...  

2018 ◽  
Vol 27 (2) ◽  
pp. 352-356 ◽  
Author(s):  
João Pedro Marto ◽  
Marlene Saraiva ◽  
Filipa Ladeira ◽  
Francisca Sá ◽  
Sofia Calado ◽  
...  

2004 ◽  
Vol 91 (05) ◽  
pp. 1031-1034 ◽  
Author(s):  
Yolanda Mira ◽  
Amparo Vayá ◽  
Dolores Corella ◽  
Fernando Ferrando ◽  
Piedad Villa ◽  
...  

SummaryThe association between factor V Leiden (FVL) and prothrombin G20210A (PT 20210) mutations and ischemic stroke remains controversial, particularly in young adults with cryptogenic stroke. Prevalence of FVL (4.1%) and PT 20210 (8.2%) mutations was assessed in 49 patients under 50 years with cryptogenic stroke and compared with controls. Odd ratio (OR) for cryptogenic stroke was 2.62 (95% CI, 0.49-13.95) for FVL and 3.75 (95% CI, 1.05-13.34) for PT 20210 and 3.28 (95% CI, 1,17-9.20) for some recognized genetic thrombophilic defect. Moreover, the OR for cryptogenic stroke in young women using oral contraceptives (OC) was 3.59 (95% CI, 1.28-10.5). When some genetic thrombophilic defect was associated with OC, the OR was much higher (OR: 14.27; 95% CI, 0.66-309.99). Our results suggest that in the Mediterranean populations the PT 20210 mutation, but not FV Leiden, is a risk factor for cryptogenic stroke in young adults. OC use is also a significant risk factor for cryptogenic stroke, which is increased in women with some genetic thrombotic risk factor.


2013 ◽  
Vol 28 (1) ◽  
pp. 59-62
Author(s):  
Hasan Zahidur Rahman ◽  
Sharif Uddin Ahmed ◽  
Mohammad Najim Uddin ◽  
Masud Rana ◽  
Anis Ahmed ◽  
...  

Stroke is the third most common cause of mortality in Westernised countries and Accounts for 12% of all deaths in the UK. The economic cost of stroke is enormous. Twelve per cent of first strokes occur in patients under 45 years of age, of which approximately 50% are ischaemic in nature. Stroke in young adult poses a major health problem. The causes of ischaemic stroke in young adults are many and diverse.Such patients usually require more extensive investigations in order to find an underlying cause than more elderly patients. Principal causes are cardioembolism, premature atherosclerosis, haematological and immunological disorders and migraine. Thrombophilic factors have been implicated in 4-8% of the young adult strokes worldwide. Protein S deficiency is a rare cause of ischemic stroke in young population. Only a few sporadic cases have been described in the literature. We are reporting a case of protein S deficiencyrelated ischemic stroke in a 40-year-old man. Early diagnosis and targeted approach can help such patients to prevent recurrent thrombotic episodes.Bangladesh Journal of Neuroscience 2012; Vol. 28 (1): 59-62


2015 ◽  
Vol 31 (2) ◽  
pp. 56-64
Author(s):  
Mostafa Hosen ◽  
Md Rafiqul Islam ◽  
Abu Nasir Rizvi ◽  
Moniruzamman Bhuyian

Background: The relation between serum lipids and ischemic stroke remains controversial in young patients. The aim was to determine the serum lipid profile and the vascular risk factors for ischaemic stroke in a series of patients under 45 with an ischemic stroke and to compare them with a series of controls of the same age. Material and method: This case-control study was conducted in the Department of Neurology and Department of Biochemistry of BSMMU, Dhaka, between the period of July 2007 and June 2009 for duration of two years. A total number of 50 patients presented with recent ischemic stroke and 50 control person were enrolled in this study. All patients of both sexes, aged between 15 to 45 years presented with ischemic stroke, from 0 day to 1 month that was confirmed by CT scan of head/MRI of brain. Vascular risk factors were recorded and blood sample was collected from the cases and the controls and analyzed at the Dept. of Biochemistry, BSMMU for estimation of serum fasting lipid profile. Result: Multivariate analyses showed that other than serum lipids- family history of dyslipidaemia, family history of stroke or TIA, history of HTN and smoking habit are found significant risks for stroke in young adult. Conclusion: The present study does not confirm the role of serum lipids as risk factors for ischemic stroke in young adult. Other than serum lipids- family history of dyslipidaemia, family history of stroke or TIA, history of HTN and smoking habit are found significant risks for stroke in young adult. Bangladesh Journal of Neuroscience 2015; Vol. 31 (2): 56-64


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