1949 LYMPH NODE YIELD USING THE STANDARD LYMPH NODE DISSECTION DURING RADICAL PROSTATECTOMY

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Guilherme Godoy ◽  
Christian von Bodman ◽  
Daher Chade ◽  
Kinjal Vora ◽  
Ozdal Dillioglugil ◽  
...  
Keyword(s):  
Lymph Node ◽  
Radical Prostatectomy ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Lymph Node Yield ◽  
Node Yield

Pathological analysis of lymph nodes in anterior prostatic fat excised at robot-assisted radical prostatectomy

2014 ◽  
Vol 67 (9) ◽  
pp. 787-791 ◽  
Author(s):  
J J Aning ◽  
R Thurairaja ◽  
D A Gillatt ◽  
A J Koupparis ◽  
E W Rowe ◽  
...  
Keyword(s):  
Lymph Node ◽  
Radical Prostatectomy ◽  
Lymph Nodes ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Robot Assisted ◽  
Lymph Node Yield ◽  
Extended Lymph Node Dissection ◽  
Pathological Analysis ◽  
Node Yield

AimsTo assess the lymph node content of anterior prostatic fat (APF) sent routinely at robot-assisted laparoscopic radical prostatectomy (RALP) and the incidence of positive nodes in the extended pelvic lymph node dissection.MethodsBetween September 2008 and April 2012, APF excised from 282 patients who underwent RALP was sent for pathological analysis. This tissue was completely embedded and lymph nodes counted.ResultsIn total, 49/282 (17%) patients had lymph nodes in the APF, median lymph node yield in this tissue was 1 (range 1–5). In four patients, the lymph nodes contained metastatic deposits. These patients did not have positive nodes elsewhere in the extended lymph node dissection.ConclusionsAPF contains lymph nodes in 1 in 6 patients and infrequently these may be malignant. APF should always be removed at radical prostatectomy. APF should be routinely sent for pathological analysis.

Clinical risk-based associations of lymph node dissection and detection of metastasis among men treated with radical prostatectomy.

2019 ◽  
Vol 37 (7_suppl) ◽  
pp. 284-284
Author(s):  
Alejandro Abello ◽  
Patrick Aloysius Kenney ◽  
Michael Leapman
Keyword(s):  
Lymph Node ◽  
Radical Prostatectomy ◽  
Lymph Node Metastasis ◽  
Node Dissection ◽  
Risk Status ◽  
Lymph Node Yield ◽  
Lymph Node Count ◽  
Node Metastasis ◽  
Node Count ◽  
Node Yield

284 Background: Pelvic lymph node dissection (PLND) is recommended for most men at risk for lymph node involvement at the time of radical prostatectomy (RP) yet is frequently omitted. We aimed to examine the probability of PLND based on clinical risk status, and evaluate the impact of increasing lymph node yield on cancer detection rate across risk strata. Methods: We queried the National Cancer Database from 2004 to 2014 to identify patients with clinically localized PCa who underwent RP as their primary treatment. We extracted patient clinical and sociodemographic variables. Risk status was assessed using UCSF Cancer of the Prostate Risk Assessment (CAPRA) score. We fit conditional logistic regression models to estimate likelihood of PLND and incremental value of increasing lymph node count by risk strata. Results: We identified 698,728 men with PCa treated with RP including 380.201 (54.41%) whit PLND. Mean age at diagnosis was 62.6. PLND was omitted (Nx) in 56.1% of patients with low CAPRA-risk disease, 31.44% with intermediate and 24.72% high. Proportion of patients with >30 lymph nodes removed decreased from 9.3% on 2004 to 3.64% on 2014. Adjusting for clinical and pathologic factors, treatment in a community versus academic (Odds Ratio, OR=1.62, 95% CI 1.59-1.66; P <0.001) and black race (OR=1.13, 95% CI 1.09-1.17, P: 0.01) was associated with pNx status. Increasing lymph node count was independently associated with greater likelihood of detection of lymph node metastasis in all risk strata (11-20 nodes: OR: 3.13 , 95% CI 2.90-3.37, P<0.001; 20-30 nodes: OR: 5.07 , 95% CI 4.50-5.73, P<0.001; >30 nodes OR: 6.58, 95% CI 5.38-8.05, P<0.001) including patients with CAPRA-0 (11-20 nodes: OR: 3.28 , 95% CI 3.06-3.53, P<0.001; 20-30 nodes: OR: 5.77, 95% CI 5.16-6.45, P<0.001; >30 nodes OR: 7.90, 95% CI 6.56-9.51, P<0.001). Conclusions: PLND continues to be omitted in a substantial proportion of intermediate and high risk patients. Increasing lymph node yield was associated with greater odds of detecting lymph node metastasis in all groups of patients, including those at the lowest level of risk by clinical criteria.

The impact of complete embedding of remaining tissue in gynecological lymph node dissection specimen in surgical pathology on lymph node yield: is it clinically relevant?

2018 ◽  
Vol 473 (2) ◽  
pp. 183-188 ◽  
Author(s):  
Julia Andruszkow ◽  
Ivo Meinhold-Heerlein ◽  
Brigitte Winkler ◽  
Benjamin Bruno ◽  
Ruth Knüchel ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
Surgical Pathology ◽  
Node Dissection ◽  
Lymph Node Yield ◽  
The Impact ◽  
Node Yield

scholarly journals Apical lymph node dissection of the inferior mesenteric artery with preservation of left colic artery in colorectal cancer

2019 ◽  
Vol 6 (2) ◽  
pp. 485
Author(s):  
Ahmed Farag El Kased ◽  
Mohammed S. Amar ◽  
Ahmed S. Elgammal ◽  
Amira M. Elfeky
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
High Ligation ◽  
Colic Artery ◽  
Node Dissection ◽  
Left Colic Artery ◽  
Lymph Node Yield ◽  
Low Ligation ◽  
Time Required ◽  
Node Yield

Background: Nowadays, surgery for colorectal cancer has been standardized both ways in open and laparoscopic approaches but there are still debates regarding the level of ligation of the IMA at its origin from aorta (high ligation) or below the origin of left colic artery (low ligation). The technique of apical lymph node dissection with preservation of LCA has the advantage of both, better lymph node harvest and lower postoperative complications. It is controversial whether a high or low ligation of the inferior mesenteric artery (IMA) is superior. The former allows an extended lymph node clearance whereas the latter preserves the distal vascular supply via the left colic artery (LCA). Apical lymph node dissection of the IMA (ALMA) harvests nodal tissue along the IMA proximal to the LCA whilst performing a low ligation. This anatomically replicates the oncological benefit of high ligation and the vascular preservation of low ligation. This study evaluates the nodal yield of ALMA and the short-term outcome of this technique.Methods: Author retrospectively studied 40 patients with operable sigmoid and rectal cancer who admitted to general surgery department in Menoufia University Hospitals from May 2016 to May 2018. All patient underwent curative surgical resection with ALMA. The lymph node yield from the dissection (the ALMA specimen) was compared with the total lymph node yield. Data on the LCA anatomy, time required to perform ALMA, complications and postoperative recovery were evaluated.Results: Results ALMA was successful in 36 patients. Median postoperative hospitalization was 5 (2-26) days without ALMA-related morbidity or mortality. The median lymph node yield was 20 (9-41) and a median of 14.3 (0-80)% were harvested with ALMA. Two patients not having neoadjuvant chemoradiotherapy had fewer than 12 lymph nodes, excluding nodes harvested from ALMA. The average time required for ALMA was 20min.Conclusions: ALMA (lymph node dissection around the IMA preserving the root of the IMA and LCA) was feasible by this method without compromising operation time, blood loss or the number of harvested lymph nodes with accepted rate of postoperative complications.

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