Re: Effect of Body Surface Decolonisation on Bacteriuria and Candiduria in Intensive Care Units: An Analysis of a Cluster-Randomised Trial

2016 ◽  
Vol 196 (1) ◽  
pp. 115-116
Author(s):  
Edward M. Schaeffer
2016 ◽  
Vol 16 (1) ◽  
pp. 70-79 ◽  
Author(s):  
Susan S Huang ◽  
Edward Septimus ◽  
Mary K Hayden ◽  
Ken Kleinman ◽  
Jessica Sturtevant ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e041799
Author(s):  
Mickael Landais ◽  
Mai-Anh Nay ◽  
Johann Auchabie ◽  
Noemie Hubert ◽  
Anne Rebion ◽  
...  

IntroductionFasting is frequently imposed to patients before extubation in the intensive care unit based on scheduled surgery guidelines. This practice has never been evaluated among critically ill patients and may delay extubation, increase nursing workload and reduce caloric intake. We are hypothesising that continuous enteral nutrition until extubation represents a safe alternative compared with fasting prior to extubation in the intensive care unit.Methods and analysisAdult patients ventilated more than 48 hours and receiving pre-pyloric enteral nutrition for more than 24 hours are included in this open-label cluster randomised parallel group non-inferiority trial. The participating centres are randomised allocated to continued enteral nutrition until extubation or 6-hour fasting (with concomitant gastric suctioning when feasible) prior to extubation. The primary outcome is extubation failure (ie, reintubation within 7 days following extubation).Ethics and disseminationThis study has been approved by the national ethics review board (comité de protection, des personnes Sud Mediterranée III No 2017.10.02 bis) and patients are included after informed consent. Results will be submitted for publication in peer-reviewed journals.Trial registration numberClinicalTrials.gov Registry (NCT03335345).


2019 ◽  
Vol 20 (2) ◽  
pp. 83-90 ◽  
Author(s):  
Shiva Gomarverdi ◽  
Mahnaz Khatiban ◽  
Ali Bikmoradi ◽  
Ali Reza Soltanian

Background: The standard precautions (SPs) should be disseminated and implemented by healthcare providers. This study aimed to examine the effects of a multi-component educational intervention on nurses’ knowledge and adherence to the SP guidelines in intensive care units (ICUs). Methods: This small-scale study consisted of a cluster randomised trial. Two ICUs, located in different hospitals, participated in the study. Nurses (n = 15) in one ICU received the multi-component educational intervention. The intervention involved an educational (with multiple instructional media) and a behavioural (with hands-on practice) component. Nurses’ knowledge and adherence were assessed at pre-test and two and six weeks after the intervention. Results: Results showed significant group by time interaction effects for both outcomes: a large improvement was found in the experimental group over time, but not in the control group. The experimental nurses’ knowledge improved from 15 ± 2.47 at pre-test to 19 ± 2.65 and 19.53 ± 0.92 at follow-ups. Similarly, their adherence increased from 19.87 ± 4.44 at pre-test to 29.20 ± 5.00 and 28.40 ± 4.37 at two and six weeks post-test, respectively. Conclusions: The multi-component educational interventions had demonstrated initial effectiveness in enhancing ICU nurses’ knowledge and adherence to the SPs guidelines. The intervention is a promising approach for designing effective continuing education initiatives aimed to improve nurses’ practice.


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