scholarly journals PIN132 HEALTH-ECONOMIC MODELLING OF INFECTIOUS DISEASE DIAGNOSTICS: CURRENT APPROACHES AND FUTURE OPPORTUNITIES

2019 ◽  
Vol 22 ◽  
pp. S660
Author(s):  
S. Van der Pol ◽  
P. Rojas ◽  
C. Juárez ◽  
A.D.I. van Asselt ◽  
F. Antoñanzas ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Health Economic ◽  
Economic Modelling ◽  
Disease Diagnostics ◽  
Infectious Disease Diagnostics ◽  
Health Economic Modelling

scholarly journals Early health economic modelling of single-stage cartilage repair. Guiding implementation of technologies in regenerative medicine

2016 ◽  
Vol 11 (10) ◽  
pp. 2950-2959 ◽  
Author(s):  
Tommy S. de Windt ◽  
Juliette C. Sorel ◽  
Lucienne A. Vonk ◽  
Michelle M. A. Kip ◽  
Maarten J. Ijzerman ◽  
...  
Keyword(s):  
Health Economic ◽  
Regenerative Medicine ◽  
Cartilage Repair ◽  
Single Stage ◽  
Economic Modelling ◽  
Early Health ◽  
Health Economic Modelling

scholarly journals It’s Not the Model, It’s the Way You Use It: Exploratory Early Health Economics Amid Complexity Comment on "Problems and Promises of Health Technologies: The Role of Early Health Economic Modelling"

2020 ◽  
Author(s):  
Andrew Partington ◽  
Jonathan Karnon
Keyword(s):  
Health Economic ◽  
Complex Interventions ◽  
Healthcare Services ◽  
Economic Modelling ◽  
Learning And Development ◽  
Health Technologies ◽  
Significant Disagreement ◽  
Early Health ◽  
Health Economic Modelling

In a review recently published in this journal, Grutters et al outline the scope and impact of their early health economic modelling of healthcare innovations. Their reflections shed light on ways that health economists can shift-away from traditional reimbursement decision-support, towards a broader role of facilitating the exploration of existing care pathways, and the design of options to implement or discontinue healthcare services. This is a crucial role in organisations that face constant pressure to react and adapt with changes to their existing service configurations, but where there may exist significant disagreement and uncertainty on the extent to which change is warranted. Such dynamics are known to create complex implementation environments, where changes risk being poorly implemented or fail to be sustained. In this commentary, we extend the discussion by Grutters et al on early health economic modelling, to the evaluation of complex interventions and systems. We highlight how early health economic modelling can contribute to a participatory approach for ongoing learning and development within healthcare organisations.

scholarly journals Third-Generation Sequencing in the Clinical Laboratory: Exploring the Advantages and Challenges of Nanopore Sequencing

2019 ◽  
Vol 58 (1) ◽  
Author(s):  
Lauren M. Petersen ◽  
Isabella W. Martin ◽  
Wayne E. Moschetti ◽  
Colleen M. Kershaw ◽  
Gregory J. Tsongalis
Keyword(s):  
Infectious Disease ◽  
Pathogen Detection ◽  
Clinical Laboratory ◽  
Low Cost ◽  
Turnaround Time ◽  
Metagenomic Sequencing ◽  
Nanopore Sequencing ◽  
Advantages And Disadvantages ◽  
Disease Diagnostics ◽  
Infectious Disease Diagnostics

ABSTRACT Metagenomic sequencing for infectious disease diagnostics is an important tool that holds promise for use in the clinical laboratory. Challenges for implementation so far include high cost, the length of time to results, and the need for technical and bioinformatics expertise. However, the recent technological innovation of nanopore sequencing from Oxford Nanopore Technologies (ONT) has the potential to address these challenges. ONT sequencing is an attractive platform for clinical laboratories to adopt due to its low cost, rapid turnaround time, and user-friendly bioinformatics pipelines. However, this method still faces the problem of base-calling accuracy compared to other platforms. This review highlights the general challenges of pathogen detection in clinical specimens by metagenomic sequencing, the advantages and disadvantages of the ONT platform, and how research to date supports the potential future use of nanopore sequencing in infectious disease diagnostics.

Current issues and future research priorities for health economic modelling across the full continuum of Alzheimer's disease

2017 ◽  
Vol 13 (3) ◽  
pp. 312-321 ◽  
Author(s):  
Anders Gustavsson ◽  
Colin Green ◽  
Roy W. Jones ◽  
Hans Förstl ◽  
Deniz Simsek ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Health Economic ◽  
Research Priorities ◽  
Future Research ◽  
Economic Modelling ◽  
Health Economic Modelling

scholarly journals How to Handle Levels of Evidence In Health Economic Modelling

2015 ◽  
Vol 18 (7) ◽  
pp. A696
Author(s):  
MJ Nuijten ◽  
M Krol ◽  
WK Redekop
Keyword(s):  
Health Economic ◽  
Economic Modelling ◽  
Levels Of Evidence ◽  
Health Economic Modelling

scholarly journals Inorganic Complexes and Metal-Based Nanomaterials for Infectious Disease Diagnostics

2018 ◽  
Vol 119 (2) ◽  
pp. 1456-1518 ◽  
Author(s):  
Christine F. Markwalter ◽  
Andrew G. Kantor ◽  
Carson P. Moore ◽  
Kelly A. Richardson ◽  
David W. Wright
Keyword(s):  
Infectious Disease ◽  
Disease Diagnostics ◽  
Infectious Disease Diagnostics ◽  
Inorganic Complexes
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