PDB9 Real World Comparison of Healthcare Resource Use of 177lutetium Oxodotretotide (LUTATHERA®) in England and Matched Cohort Analysis of Progressive Neuroendocrine Tumour Patients Using the Hospital Episodes Statistics Database

2021 ◽  
Vol 24 ◽  
pp. S79
Author(s):  
T. Cox ◽  
M. O'Connell ◽  
O. Leeuwenkamp ◽  
S. Palimaka ◽  
N. Reed
2015 ◽  
Vol 4 ◽  
pp. 1-12 ◽  
Author(s):  
Allicia Girvan ◽  
Gebra Carter ◽  
Li Lin ◽  
Anna Kaltenboeck ◽  
Jasmina Ivanova ◽  
...  

2021 ◽  
pp. 1-8
Author(s):  
Han-I. Wang ◽  
Lu Han ◽  
Rowena Jacobs ◽  
Tim Doran ◽  
Richard I. G. Holt ◽  
...  

Background Approximately 60 000 people in England have coexisting type 2 diabetes mellitus (T2DM) and severe mental illness (SMI). They are more likely to have poorer health outcomes and require more complex care pathways compared with those with T2DM alone. Despite increasing prevalence, little is known about the healthcare resource use and costs for people with both conditions. Aims To assess the impact of SMI on healthcare resource use and service costs for adults with T2DM, and explore the predictors of healthcare costs and lifetime costs for people with both conditions. Method This was a matched-cohort study using data from the Clinical Practice Research Datalink linked to Hospital Episode Statistics for 1620 people with comorbid SMI and T2DM and 4763 people with T2DM alone. Generalised linear models and the Bang and Tsiatis method were used to explore cost predictors and mean lifetime costs respectively. Results There were higher average annual costs for people with T2DM and SMI (£1930 higher) than people with T2DM alone, driven primarily by mental health and non-mental health-related hospital admissions. Key predictors of higher total costs were older age, comorbid hypertension, use of antidepressants, use of first-generation antipsychotics, and increased duration of living with both conditions. Expected lifetime costs were approximately £35 000 per person with both SMI and T2DM. Extrapolating nationally, this would generate total annual costs to the National Health Service of around £250 m per year. Conclusions Our estimates of resource use and costs for people with both T2DM and SMI will aid policymakers and commissioners in service planning and resource allocation.


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