scholarly journals Quantification of left atrial contractile function using two-dimensional speckle tracking echocardiography in horses after conversion of atrial fibrillation to sinus rhythm

Author(s):  
C. Eberhardt ◽  
C.C. Schwarzwald
2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Mengruo Zhu ◽  
Haiyan Chen ◽  
Yang Liu ◽  
Xianhong Shu

Abstract Background To evaluate left atrial (LA) phasic functions in patients with hypertension and/or paroxysmal atrial fibrillation (PAF) and its clinical significance. Methods LA strain was studied in 77 patients (25 hypertension, 24 lone AF, and 28 with both hypertension and PAF) and 28 controls using two-dimensional speckle-tracking echocardiography (2D STE). The following indexes during atrial reservoir, conduit and pump phase were analyzed respectively: (1) peak atrial longitudinal strain (PALS) and strain rate (PALSR), (2) the standard deviation of time to PALS and PALSR of all LA segments (TpS-SD% and TpSR-SD%). Results Compared with controls, PALSres, PALScond and PALSRcond were significantly reduced in patients with isolated hypertension (all P < 0.01) but no significant differences were observed in PALSpump, PALSRpump and TpSpump-SD% between them (all P > 0.05). PALSpump, PALSRpump and PALSRres were significantly lower in patients with both hypertension and PAF than in those with isolated hypertension (all P < 0.05). PALS and PALSR were significantly decreased, and TpS-SD% was significantly increased during each phase in lone AF patients than in controls (all P < 0.05), and PALSRpump was further depressed in patients with both hypertension and PAF (P = 0.029). PALSRcond ≤ 1.475 s− 1 combined with TpSpump-SD% ≥ 3.25% (sensitivity, 85%; specificity, 71%; AUC = 0.845, P < 0.001) could distinguish lone AF from healthy subjects effectively, while in hypertensive patients, PALSpump ≤ 14.2% was found to be an independent differentiator for occurrence of AF or not with sensitivity of 81% and specificity of 84% (AUC = 0.838, P < 0.001). LAVI≥29.3 mL/m2 was an independent characteristic for reflecting different LA remodeling in lone AF or hypertension with AF. Conclusions The impairment of LA phasic functions was varied in patients with hypertension and/or AF. The disturbed LA phasic functions were proved to have independent abilities of differential diagnosis in this heterogeneous population associated with hypertension or AF.


Author(s):  
VIMAL MEHTA ◽  
Dhanjibhai Chaudhari ◽  
Pratishtha Mehra ◽  
Sudhanshu Mahajan ◽  
Jamal Yusuf ◽  
...  

Aim: The aim of this study was to assess the left atrial (LA) function in severe rheumatic mitral stenosis (MS) patients using two-dimensional speckle tracking echocardiography (STE) and its correlation with clinical symptoms and echocardiography parameters. Methods: A total of 120 subjects (80 patients with isolated severe MS [mitral valve area (MVA) ≤1.5 cm2] in sinus rhythm and 40 healthy controls) underwent comprehensive echocardiography including STE for assessment of LA strain [reservoir strain (LASr), conduit strain (LAScd) and contractile strain (LASct)]. Results: The mean MVA in cases was 0.93 ± 0.21 cm2. The mean values of LASr (14.73 ± 8.59%), LAScd (-7.61 ± 4.47%) and LASct (-7.16 ± 5.15%) among cases were significantly less (p< 0.001) when compared to controls where the values were 44.11 ± 10.44%, -32.45 ± 7.63%, -11.85 ± 6.77% respectively. Thus the compensatory LA contractile function was also compromised. The New York Heart Association (NYHA) class III, II and I dyspnea was present in 37 (46.25%), 38 (47.5%) and 5 (6.25%) subjects respectively. All the three LA strain parameters showed a trend towards decline with increase in severity of MS, increase in LA size, increase in mean and peak diastolic transmitral gradients and with higher NYHA functional class. Conclusion: Left atrial dysfunction is common in severe rheumatic MS as suggested by severely reduced LA reservoir, conduit and contractile strain. Early and timely intervention in these patients irrespective of NYHA functional class is advocated as it may likely improve the LA function and avoid clinical deterioration.


2017 ◽  
Vol 19 (12) ◽  
pp. 1283-1289 ◽  
Author(s):  
Ryohei Suzuki ◽  
Yohei Mochizuki ◽  
Hiroki Yoshimatsu ◽  
Takahiro Teshima ◽  
Hirotaka Matsumoto ◽  
...  

Objectives Hypertrophic cardiomyopathy, a primary disorder of the myocardium, is the most common cardiac disease in cats. However, determination of myocardial deformation with two-dimensional speckle-tracking echocardiography in cats with various stages of hypertrophic cardiomyopathy has not yet been reported. This study was designed to measure quantitatively multidirectional myocardial deformations of cats with hypertrophic cardiomyopathy. Methods Thirty-two client-owned cats with hypertrophic cardiomyopathy and 14 healthy cats serving as controls were enrolled and underwent assessment of myocardial deformation (peak systolic strain and strain rate) in the longitudinal, radial and circumferential directions. Results Longitudinal and radial deformations were reduced in cats with hypertrophic cardiomyopathy, despite normal systolic function determined by conventional echocardiography. Cats with severely symptomatic hypertrophic cardiomyopathy also had lower peak systolic circumferential strain, in addition to longitudinal and radial strain. Conclusions and relevance Longitudinal and radial deformation may be helpful in the diagnosis of hypertrophic cardiomyopathy. Additionally, the lower circumferential deformation in cats with severe hypertrophic cardiomyopathy may contribute to clinical findings of decompensation, and seems to be related to severe cardiac clinical signs. Indices of multidirectional myocardial deformations by two-dimensional speckle-tracking echocardiography may be useful markers and help to distinguish between cats with hypertrophic cardiomyopathy and healthy cats. Additionally, they may provide more detailed assessment of contractile function in cats with hypertrophic cardiomyopathy.


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