What Evidence Should We Demand before Accepting a New Embolic Material for Uterine Artery Embolization?

2009 ◽  
Vol 20 (5) ◽  
pp. 567-570 ◽  
Author(s):  
James B. Spies
2021 ◽  
Vol 2 (69) ◽  
pp. 92
Author(s):  
Gabriel Octavian Olaru ◽  
Monica-Cătălina Pena ◽  
Liana Pleș ◽  
Romina-Marina Sima ◽  
Cristian-Viorel Poalelungi

2021 ◽  
Vol 9 (3) ◽  
Author(s):  
Jaron Tepper ◽  
Jacob Cynamon

Uterine artery embolization (UAE) is a well-accepted treatment for symptomatic uterine fibroids, but endpoints of UAE remain controversial. This is of significant concern as incomplete embolization can lead to treatment failure, necessitating repeat embolization or alternative treatments such as hysterectomy. Multiple potential causes of UAE failure have been described including failure to catheterize one or both of the uterine arteries, uterine artery spasm, clumping of embolic material and collateral blood supply vascularizing the fibroids. In this review, we discuss potential approaches to identifying collateral blood supply to the uterus and suggest that intra-procedural non-contrast cone beam CT provides unique advantages to addressing this issue.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Xiao An ◽  
Xu Ming ◽  
Ke Li ◽  
Jingbing Wang

Objectives. This study observes therapeutic efficacy of uterine artery embolization combined with MTX infusion which terminates cesarean scar pregnancy (CSP) and induces three factors which probably relate to failure.Methods. Twenty-three CSP patients were treated with combined uterine artery MTX infusion and embolization. Among them six patients with severe hemorrhage were immediately treated with interventional operation. Clinical effects were estimated by symptoms, serum -hCG, ultrasound, and MR.Results. Interventional treatments were technologically successful in 22 patients except one. Immediate hemostasis was achieved in all 6 patients with massive colporrhagia. No occurrence of infection and uterine necrosis was observed, but 12 women suffered abdominal pains. Nineteen patients’ uteri were preserved, whereas four underwent hysterectomy eventually.Conclusions. Transcatheter arterial chemoembolization is effective to treat high-risk CSP in preference to hysterectomy. To achieve more successful outcomes, three factors should be highlighted: adequate MTX dosage, appropriate embolic material, and complete embolization of target arteries that supply blood to embryo in the scar.


2020 ◽  
Vol 4 ◽  
pp. 8
Author(s):  
Jemianne Bautista Jia ◽  
Eric Mastrolonardo ◽  
Mateen Soleman ◽  
Ilya Lekht

Contrast-enhanced ultrasound (CEUS) is a cost-effective, quick, and non-invasive imaging modality that has yet to be incorporated in uterine artery embolization (UAE). We present two cases that demonstrate the utility of CEUS in UAE for the identification of uterine-ovarian collaterals which otherwise can result in ineffective fibroid treatment and non-target embolization.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (1) ◽  
pp. 78-82
Author(s):  
G P Titova ◽  
M M Damirov ◽  
L S Kokov ◽  
O N Oleynikova ◽  
G E Belozerov

Uterine leiomyoma (UL) is often complicated by the development of uterine bleeding. In urgent gynecology for the implementation of endovascular hemostasis, uterine artery embolization (UAE) is used. Performing UAE allows to stop and/or significantly reduce the intensity of bleeding and prepare a patient for surgical intervention. At the same time, the morphological changes that occur in uterine tissues in operated UL patients after performing the UAE are not studied. The aim was to study the peculiarities of pathomorphological changes in uterine tumors and tissues in operated UL patients complicated by uterine bleeding after performing UAE. Material and methods. The results of morphological changes appearing in tumors and tissues of the uterus in 39 operated UL patients, who were used for stopping uterine bleeding, were analyzed. Results. After applying different types of embolizing agents in macroscopic study of the uterus, signs of ischemia of its tissues were revealed, and the most pronounced disorders were detected in the UL nodes. Morphologically it was established that UAE microemboli resulted in vessel occlusion with increasing thrombosis in their distal sections. UAE was not accompanied by occlusal occlusion of the arteries and resulted in small-scale necrosis of the tumor with complete regeneration of the endometrium. Conclusions. The results of the morphological study showed that after the UAE was performed, the myomatous nodes underwent dystrophic, necrobiotic and necrotic changes. Depending on the nature of occlusion of the uterine arteries, various variants of necrosis (scale and completeness of the process) developed in the tumor tissue, which was aseptic in nature.


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