Enhanced immune responses in pigs by DNA vaccine coexpressing GP3 and GP5 of European type porcine reproductive and respiratory syndrome virus

2014 ◽  
Vol 206 ◽  
pp. 27-37 ◽  
Author(s):  
Jingqiang Ren ◽  
Huijun Lu ◽  
Shubo Wen ◽  
Wenchao Sun ◽  
Fulong Yan ◽  
...  
Keyword(s):  
Immune Responses ◽  
Dna Vaccine ◽  
Respiratory Syndrome Virus

scholarly journals A polyvalent influenza DNA vaccine applied by needle-free intradermal delivery induces cross-reactive humoral and cellular immune responses in pigs

Vaccine ◽  
2016 ◽  
Vol 34 (32) ◽  
pp. 3634-3640 ◽  
Author(s):  
Marie Borggren ◽  
Jens Nielsen ◽  
Ingrid Karlsson ◽  
Tina S. Dalgaard ◽  
Ramona Trebbien ◽  
...  
Keyword(s):  
Immune Responses ◽  
Dna Vaccine ◽  
Cellular Immune Responses ◽  
Intradermal Delivery ◽  
Cellular Immune

scholarly journals Porcine Reproductive and Respiratory Syndrome Virus: Immune Escape and Application of Reverse Genetics in Attenuated Live Vaccine Development

Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 480
Author(s):  
Honglei Wang ◽  
Yangyang Xu ◽  
Wenhai Feng
Keyword(s):  
Immune Responses ◽  
Reverse Genetics ◽  
Vaccine Development ◽  
Immune Escape ◽  
Rna Virus ◽  
Economic Losses ◽  
Respiratory Syndrome Virus ◽  
Live Vaccines ◽  
Host Immune Responses ◽  
Inactivated Vaccines

Porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus widely prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from the host immune response in several processes. Vaccines, including modified live vaccines and inactivated vaccines, are the best available countermeasures against PRRSV infection. However, challenges still exist as the vaccines are not able to induce broad protection. The reason lies in several facts, mainly the variability of PRRSV and the complexity of the interaction between PRRSV and host immune responses, and overcoming these obstacles will require more exploration. Many novel strategies have been proposed to construct more effective vaccines against this evolving and smart virus. In this review, we will describe the mechanisms of how PRRSV induces weak and delayed immune responses, the current vaccines of PRRSV, and the strategies to develop modified live vaccines using reverse genetics systems.

scholarly journals Comparison of immune responses against FMD by a DNA vaccine encoding the FMDV/O/IRN/2007 VP1 gene and the conventional inactivated vaccine in an animal model

2012 ◽  
Vol 27 (5) ◽  
pp. 286-291
Author(s):  
Farahnaz Motamedi Sedeh ◽  
Hoorieh Soleimanjahi ◽  
AmirReza Jalilian ◽  
Homayoon Mahravani
Keyword(s):  
Animal Model ◽  
Immune Responses ◽  
Dna Vaccine ◽  
Inactivated Vaccine ◽  
Vp1 Gene

Enhancement of VP1-specific immune responses and protection against EMCV-K challenge by co-delivery of IL-12 DNA with VP1 DNA vaccine

Vaccine ◽  
2001 ◽  
Vol 19 (15-16) ◽  
pp. 1891-1898 ◽  
Author(s):  
You-Suk Suh ◽  
Sang-Jun Ha ◽  
Chu-Hee Lee ◽  
Jeong-Im Sin ◽  
Young-Chul Sung
Keyword(s):  
Immune Responses ◽  
Dna Vaccine

scholarly journals Ag85A DNA Vaccine Delivery by Nanoparticles: Influence of the Formulation Characteristics on Immune Responses

Vaccines ◽  
2016 ◽  
Vol 4 (3) ◽  
pp. 32 ◽  
Author(s):  
Johanna Poecheim ◽  
Christophe Barnier-Quer ◽  
Nicolas Collin ◽  
Gerrit Borchard
Keyword(s):  
Immune Responses ◽  
Dna Vaccine ◽  
Vaccine Delivery

scholarly journals Targeting with Bovine CD154 Enhances Humoral Immune Responses Induced by a DNA Vaccine in Sheep

2003 ◽  
Vol 170 (2) ◽  
pp. 989-996 ◽  
Author(s):  
Sharmila Manoj ◽  
Philip J. Griebel ◽  
Lorne A. Babiuk ◽  
Sylvia van Drunen Littel-van den Hurk
Keyword(s):  
Immune Responses ◽  
Dna Vaccine ◽  
Humoral Immune ◽  
Humoral Immune Responses
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