scholarly journals A Deep Dive into the Meaning of the Renal Resistive Index, its Limited Correlation With Renal Function, and a Theoretical Way Forward to Improve its Usefulness

2021 ◽  
Vol 74 (4) ◽  
pp. e381-e382
Author(s):  
Alan P. Sawchuk ◽  
Whitney Yu ◽  
John Talamantes ◽  
Weichen Hong ◽  
Dave Rollins ◽  
...  
Keyword(s):  
Renal Function ◽  
Resistive Index ◽  
Renal Resistive Index ◽  
Deep Dive

Abstract P358: Association of Kidney Function and Cerebral Arterial Stiffness

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Eung-Joon Lee ◽  
Hae Bong Jeong ◽  
Ki-woong Nam ◽  
Kipyoung Jeon ◽  
Jeonghoon Bae ◽  
...  
Keyword(s):  
Renal Function ◽  
Arterial Stiffness ◽  
Renal Dysfunction ◽  
Doppler Ultrasound ◽  
Resistive Index ◽  
Retrospective Chart Review ◽  
Transcranial Doppler Ultrasound ◽  
Lacunar Infarction ◽  
Renal Resistive Index ◽  
Proportional Relationship

Background and Purpose: Chronic kidney disease (CKD) is known to have affected the systemic vasculature and its remodeling, which eventually led to the systemic arterial stiffness. However, the relationship between cerebral circulation and impaired renal function is poorly understood. To evaluate the effect of renal dysfunction to increase systemic and intracranial arterial stiffness, we assessed the relation between renal resistive index (RRI) and pulsatility index (PI) of the middle cerebral artery (MCA). Methods: We included patients with acute lacunar infarction. Demographic and clinical data were collected by retrospective chart review. Bilateral transcranial Doppler ultrasound (TCD) examination of the MCAs was performed using the ST3 Ultrasound system (Spencer Technologies) and PI were calculated. RRI was obtained through kidney Doppler sonography. Subjects with occlusion or significant stenosis of MCA, atrial fibrillation, bilaterally absent transtemporal sonographic windows were excluded. Results: Of the 283 included subjects (mean age 67.8 ± 10.2), 74 patients had renal dysfunction (glomerular filtration rate < 60ml/min/1.73m2 at admission) and 49 patients underwent kidney Doppler ultrasound within 1 year since their acute stroke. Renal dysfunction was significantly associated with higher arterial stiffness (median PI 1.12, IQR 0.85 to 1.57 vs. controls PI 0.84, IQR 0.54 to 1.22 [p<0.0001]). There was a proportional relationship between the degree of renal dysfunction and the distal vascular resistance. In multivariate adjusted regression analysis, renal function was related to high PI (p<0.001). Furthermore, there is strong correlation between RRI and PI ( r =0.65, p <0.001). Conclusions: In patients with lacunar infarction, renal impairment is an independent determinant of increased arterial stiffness in cerebral circulations. In addition, PI is significantly associated with RRI.

Impact of mild hypoxemia on renal function and renal resistive index during mechanical ventilation

2009 ◽  
Vol 35 (6) ◽  
pp. 1031-1038 ◽  
Author(s):  
Michael Darmon ◽  
Frédérique Schortgen ◽  
Rusel Leon ◽  
Stéphane Moutereau ◽  
Julien Mayaux ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Renal Function ◽  
Resistive Index ◽  
Renal Resistive Index

scholarly journals THE CORRELATION OF RENAL RESISTIVE INDEX AND SERUM CREATININE IN PREDICTING RENAL FUNCTION IN ACUTE URETERAL OBSTRUCTION

2018 ◽  
pp. 4501-4504
Author(s):  
Ravikumar Jadhav ◽  
Nirmit Agrawal ◽  
Ishwar Hosamani ◽  
Sampathkumar Nathee ◽  
Udaykumar Udaykumar ◽  
...  
Keyword(s):  
Renal Function ◽  
Serum Creatinine ◽  
Ureteral Obstruction ◽  
Resistive Index ◽  
Renal Resistive Index

scholarly journals The Resistive Index Is a Marker of Renal Function, Pathology, Prognosis, and Responsiveness to Steroid Therapy in Chronic Kidney Disease Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Kikuno Hanamura ◽  
Akihiro Tojo ◽  
Satoshi Kinugasa ◽  
Kensuke Asaba ◽  
Toshiro Fujita
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Steroid Therapy ◽  
Resistive Index ◽  
Prognostic Indicator ◽  
Renal Resistive Index ◽  
Renal Survival ◽  
Histological Damage ◽  
Ckd Stage

To evaluate the significance of the renal resistive index (RI) as a noninvasive marker of renal histological damage and a prognostic indicator, we examined RI by Doppler ultrasonography in 202 chronic kidney disease (CKD) patients who underwent renal biopsy. RI increased as the CKD stage progressed and correlated with age, systolic blood pressure, estimated glomerular filtration rate (eGFR), and renal histological changes, including glomerulosclerosis, arteriolosclerosis, and tubulointerstitial damage. Prognostic evaluation with a median follow-up period of 38.5 months revealed that patients withRI≥0.7(high RI group,n=39) had significantly poorer renal survival than those withRI<0.65(normal RI group,n=120) and0.65≤RI<0.7(high-normal RI group,n=43). The patients in the high-normal RI group showed good response to steroids. However, in the high RI group, steroid therapy did not significantly improve renal survival. Of the clinical indices studied,RI≥0.7, hypertension, proteinuria, and low eGFR at diagnosis were independent risk factors for worsening renal dysfunction. In conclusion, RI in CKD patients was considered as a marker of renal function, histological damage, and renal prognosis, and a possible determinant of indication for steroids.

Renal Resistive Index and Parathyroid Hormone Relationship with Renal Function in Nondiabetic Patients

2011 ◽  
Vol 37 (2) ◽  
pp. 47-58 ◽  
Author(s):  
Guglielmo M. Trovato ◽  
Giuseppe Fabio Martines ◽  
Francesca M. Trovato ◽  
Clara Pirri ◽  
Patrizia Pace ◽  
...  
Keyword(s):  
Renal Function ◽  
Parathyroid Hormone ◽  
Resistive Index ◽  
Renal Resistive Index

P1711RENAL RESISTIVE INDEX (RRI) OF KIDNEY ALLOGRAFT. OMEN OF THE OUTCOME OF TRANSPLANTION?

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Maria Smyrli ◽  
Glykeria Tsouka ◽  
Theodora Oikonomaki ◽  
Vasileios Vougas ◽  
Theofanis Apostolou ◽  
...  
Keyword(s):  
Renal Function ◽  
Medical Center ◽  
Graft Function ◽  
Resistive Index ◽  
Renal Resistive Index ◽  
First Year ◽  
Kidney Allograft ◽  
The Third ◽  
Reduced Frequency ◽  
One Year

Abstract Background and Aims Renal resistive index (RRI) of ultrasonography is a useful and potent tool for assessment and evaluation of renal hyperfiltration status of the transplanted patients. The aim of this study was to evaluate the association of RRI with renal function one year after transplant. Method We evaluated retrospectively 98 kidney allograft recipients. Data were collected from transplantations performed in our medical center between 01/2014 and 09/2018. Patients with acute loss of the renal function and renal survival less than a year were excluded from the study. We compared longitudinally the RRI at the first week after transplant and the third month, with glomerular filtration rate (eGFR, by CKD-EPI) at the end of the first year of transplantation. RRI was measured on the interlobular artery level, in each of the aforementioned time periods, and results were classified into 2 groups, RRI &lt;0,8 or&gt;0,8. In addition, age, gender and delayed graft function (DGF) were also determined in all patients. Results Sixty seven (67) of the recipients were males and 31 females with a mean age of 48±12years. The corresponding demographics for the donors were 46 males and 52 females with a mean age of 53 ±14. No correlations were found between RRI of the first week with gender and age, of both donors and recipients (p&gt;0.05). Similarly, RRI of the first week was not correlated with DGF and one-year eGFR after transplant (p&gt;0.05). On the contrary, RRI performed at the third month was strongly correlated to DGF and eGFR at the end of the first year. In other words, allograft recipients with a resistive index less than 0.80, had a higher eGFR and reduced frequency of DGF (p=0.01 and 0.03 respectively). Last but not least, higher recipient age and not gender was the main determinant of an increase of resistive index in the third month after transplant (P=0.02). Conclusion RRI offers interesting and helpful data on kidney allograft function. RRI of the third month less than 0.8 was related to better renal function at the end of the first year after transplant mainly and a lower incidence of DGF.

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