scholarly journals The impact of publicly funded immunization programs on human papillomavirus vaccination in boys and girls: An observational study

2021 ◽  
pp. 100128
Author(s):  
Gilla K. Shapiro ◽  
Ovidiu Tatar ◽  
Bärbel Knäuper ◽  
Gabrielle Griffin-Mathieu ◽  
Zeev Rosberger
Keyword(s):  
Human Papillomavirus ◽  
Observational Study ◽  
Publicly Funded ◽  
Immunization Programs ◽  
Human Papillomavirus Vaccination ◽  
The Impact

scholarly journals The impact of publicly funded rotavirus immunization programs on Canadian children

2021 ◽  
Vol 47 (2) ◽  
pp. 97-104
Author(s):  
Pia K Muchaal ◽  
Matt Hurst ◽  
Shalini Desai
Keyword(s):  
Hospital Discharge ◽  
Prince Edward Island ◽  
Public Funding ◽  
Surveillance Program ◽  
Rotavirus Vaccine ◽  
Publicly Funded ◽  
Immunization Programs ◽  
Hospital Discharges ◽  
Discharge Data ◽  
The Impact

Background: In 2008, the National Advisory Committee on Immunization recommended routine rotavirus immunizations in healthy Canadian infants. Over the following seven years, eight provinces and two territories introduced the rotavirus vaccine into their publicly funded immunization programs. Objective: Assess the burden of rotavirus infections before and after implementation of publicly funded immunization programs. Methods: We analyzed laboratory-confirmed community cases of rotavirus reported to the National Enteric Surveillance Program and hospitalizations of children younger than three years old from 2007 to 2017 with rotavirus diagnosis-specific ICD-10 codes. Rates of illness were calculated for each province for the two years prior to and after implementation of public funding of the vaccine. The year of implementation was not included to accommodate the uptake period of the vaccine. Age-specific rates were assessed in jurisdictions where five years of data were available the year after the vaccine was publicly funded. The pre–post and difference-in-difference (DID) methodologies were applied to hospital discharge data to evaluate changes between the funding and non-funding jurisdictions. Results: Community cases of laboratory-confirmed rotavirus infection reported to the National Enteric Surveillance Program declined by 54% between 2010 and 2017. Rates of hospital discharges decreased significantly among children in six provinces after the adoption of the rotavirus vaccine. Hospital discharge rates in Alberta, Manitoba, Ontario and Prince Edward Island dropped between 53% and 71%, and by 75% for British Columbia and Saskatchewan. Conclusion: Public funding of the rotavirus vaccine appeared to lead to significant reductions in laboratory-confirmed rotavirus cases reported to the National Enteric Surveillance Program and in the rates of rotavirus gastroenteritis-related hospital discharges.

One-Dose Human Papillomavirus Vaccination and the Risk of Genital Warts: A Danish Nationwide Population-based Study

2020 ◽  
Author(s):  
Louise Baandrup ◽  
Christian Dehlendorff ◽  
Susanne K Kjaer
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Age Groups ◽  
Genital Warts ◽  
Population Based ◽  
Incidence Rates ◽  
Real World Data ◽  
Calendar Time ◽  
Human Papillomavirus Vaccination ◽  
The Impact

Abstract Background Increasing evidence suggests that 1-dose human papillomavirus (HPV) vaccination may protect significantly against HPV-related disease. We provide nationwide, real-world data on the risk of genital warts (GWs) after <3 vaccine doses. Methods All Danish women born in 1985–2003 were identified, and individual-level vaccination data were retrieved. The cohort was followed up for first occurrence of GWs until 31 December 2016. Using Poisson regression, we calculated incidence rates (IRs) of GWs per 100 000 person-years and IR ratios (IRRs) with corresponding 95% confidence intervals (CIs) for GWs, according to vaccination status, age at first dose, and calendar time. Results The cohort comprised 1 076 945 girls and women, of whom 485 408 were vaccinated. For girls initiating vaccination at age 12–14 years and 15–16 years, 1-dose vaccine effectiveness (VE) was 71% (IRR = 0.29; 95% CI, .22–.38) and 62% (0.38; .29–.49), respectively, compared with unvaccinated girls. In the same age groups, 2-dose VE was 78% (IRR, 0.22; 95% CI, .18–.26) and 68% (0.32; .26–.38), respectively. After 2009, the IRRs for 3 versus 1 dose and 2 versus 1 dose increased towards unity over calendar time, being 0.69 (95% CI, .57–.84) and 0.86 (.68–1.08) in 2016, respectively. Conclusions In this study, 1 or 2 doses of quadrivalent HPV vaccine was associated with substantial protection against GWs in girls vaccinated at age ≤16 years. The 1-dose VE approached that of 3 or 2 doses over calendar time, probably reflecting the impact of herd protection.

Factors influencing rates of human papillomavirus vaccination

2019 ◽  
Author(s):  
Kelsey E Palmer ◽  
Krystal L Moorman ◽  
Nancy A Nickman ◽  
David G Owen
Keyword(s):  
Human Papillomavirus ◽  
Failure Modes ◽  
Hpv Vaccination ◽  
Care Process ◽  
Quality Improvement Initiative ◽  
Human Papillomavirus Vaccination ◽  
Community Clinic ◽  
Process Improvements ◽  
The Impact

Abstract Purpose Failure modes and effects analysis (FMEA) was used to identify ways in which community clinic practices related to suboptimal human papillomavirus (HPV) vaccination rates could be improved. Method FMEA is a standardized safety method that helps determine where processes fail, the impact of failures, and needed process changes. In a quality improvement initiative conducted at an academic health center–based community clinic, a multidisciplinary team used FMEA to map HPV vaccination processes and identify areas for improvement of vaccination practices. Risk priority numbers (RPNs) were assigned to identified failure modes based on likelihood of occurrence, likelihood of detection, and ability to correct locally. Failure modes with the highest RPNs were targeted for process improvements. Results High RPN failure modes were related to clinic processes for follow-up, immunization status checks during well-child visits, and vaccination discussions during sick-child visits. New procedures included scheduling follow-up vaccinations and reminders during the initial vaccination appointment. HPV immunization rates improved following implementation of these procedures, indicating that clinic processes focused on patient follow-up can impact vaccination series completion. Conclusion FMEA processes can help health systems identify workflow barriers and locally relevant opportunities for improvement. Team-based approaches to care process improvements can also benefit from standardized problem identification and solving.

scholarly journals Maximizing the Impact of Human Papillomavirus Vaccination

2017 ◽  
Vol 65 (6) ◽  
pp. 890-892
Author(s):  
Suzanne M Garland ◽  
Dorothy A Machalek
Keyword(s):  
Human Papillomavirus ◽  
Human Papillomavirus Vaccination ◽  
The Impact

scholarly journals PIN13 ESTIMATING THE IMPACT OF A GENDER-NEUTRAL QUADRIVALENT HUMAN PAPILLOMAVIRUS VACCINATION PROGRAM IN ALL HPV 6/11/16/18 -RELATED DISEASES IN COLOMBIA

2020 ◽  
Vol 23 ◽  
pp. S170-S171
Author(s):  
M. Carrasquilla ◽  
N.J. Alvis-Zakzuk ◽  
J. Zakzuk Sierra ◽  
F. Gómez De la Rosa ◽  
C. Beltran ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Vaccination Program ◽  
Human Papillomavirus Vaccination ◽  
Gender Neutral ◽  
The Impact

scholarly journals The impact of human papillomavirus vaccination on cervical cancer prevention efforts

2009 ◽  
Vol 114 (2) ◽  
pp. 360-364 ◽  
Author(s):  
L. Stewart Massad ◽  
Mark Einstein ◽  
Evan Myers ◽  
Cosette M. Wheeler ◽  
Nicolas Wentzensen ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Cancer Prevention ◽  
Cervical Cancer Prevention ◽  
Human Papillomavirus Vaccination ◽  
The Impact

Outreach and Reminders to Improve Human Papillomavirus Vaccination in an Integrated Primary Care System

2018 ◽  
Vol 57 (13) ◽  
pp. 1523-1531 ◽  
Author(s):  
Nora B. Henrikson ◽  
Weiwei Zhu ◽  
Lauren Baba ◽  
Matthew Nguyen ◽  
Heidi Berthoud ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Health System ◽  
Hpv Vaccine ◽  
Hpv Vaccination ◽  
Intervention Group ◽  
Human Papillomavirus Vaccination ◽  
Vaccine Initiation ◽  
Series Completion ◽  
And Control ◽  
The Impact

This study evaluated the impact of health system–based outreach and reminders on human papillomavirus (HPV) vaccine series initiation and completion. Parents of 10 to 12 year olds (n = 1805) were randomized to receive either (1) an outreach letter and brochure recommending HPV vaccination followed by automated HPV vaccine reminders or (2) usual care. We interviewed a subset of 50 parents to assess program acceptability. Outcomes were HPV vaccine initiation during the study period and on-time series completion. Rates of HPV vaccine initiation during the study period (July 2015 to August 2016) were similar between the intervention and control groups, but initiation within 120 days of randomization was higher in the intervention group (23.6% and 18.8%, P = .04) as was completion during the study period (10.3% vs 6.8%, P = .04). Reminders for doses 2 and 3 did not affect completion. The program was acceptable to parents. This study provides evidence that health system–based outreach and reminders can improve HPV vaccination.

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