EphA4 is highly expressed in the atria of heart and its deletion leads to atrial hypertrophy and electrocardiographic abnormalities in rats

Life Sciences ◽  
2021 ◽  
pp. 119595
Author(s):  
Jingwen Li ◽  
Wei Dong ◽  
Xiang Gao ◽  
Wei Chen ◽  
Caixian Sun ◽  
...  
Keyword(s):  
Electrocardiographic Abnormalities

COVID-19-associated multisystem inflammatory syndrome in children presenting uniquely with sinus node dysfunction in the setting of shock

2021 ◽  
pp. 1-3
Author(s):  
Lesya G. Tomlinson ◽  
Mitchell I. Cohen ◽  
Rebecca E. Levorson ◽  
Megan B. Tzeng
Keyword(s):  
Inflammatory Process ◽  
Myocardial Dysfunction ◽  
Sinus Node ◽  
Qtc Prolongation ◽  
Mild Disease ◽  
Abnormal Immune Response ◽  
Idioventricular Rhythm ◽  
Inflammatory Syndrome ◽  
Electrocardiographic Abnormalities ◽  
Post Infectious

Abstract SARS-CoV-2, which causes the disease COVID-19, generally has a mild disease course in children. However, a severe post-infectious inflammatory process known as multisystem inflammatory syndrome in children has been observed in association with COVID-19. This inflammatory process is a result of an abnormal immune response with similar clinical features to Kawasaki disease. It is well established that multisystem inflammatory syndrome in children is associated with myocardial dysfunction, coronary artery dilation or aneurysms, and occasionally arrhythmias. The most common electrocardiographic abnormalities seen include premature atrial or ventricular ectopy, variable degrees of atrioventricular block, and QTc prolongation, and rarely, haemodynamically significant arrhythmias necessitating extracorporeal membrane oxygenation support. However, presentation with fever, hypotension, and relative bradycardia with a left axis idioventricular rhythm has not been previously reported. We present a case of a young adolescent with multisystem inflammatory syndrome in children with myocarditis and a profoundly inappropriate sinus node response to shock with complete resolution following intravenous immunoglobulin.

Comprehensive non-invasive assessment of electrocardiographic abnormalities and cardiac arrhythmias in patients with genetically confirmed mitochondrial diseases

2021 ◽  
Vol 65 ◽  
pp. 136-142
Author(s):  
Piotr Bienias ◽  
Olga Zdończyk ◽  
Biruta Kierdaszuk ◽  
Anna Maria Gawałkiewicz ◽  
Marta Jaworska ◽  
...  
Keyword(s):  
Cardiac Arrhythmias ◽  
Mitochondrial Diseases ◽  
Non Invasive ◽  
Electrocardiographic Abnormalities

scholarly journals The Value of Electrocardiographic Abnormalities in the Prognosis of Pulmonary Embolism: A Consensus Paper

2015 ◽  
Vol 20 (3) ◽  
pp. 207-223 ◽  
Author(s):  
Geneviève C. Digby ◽  
Piotr Kukla ◽  
Zhong-Qun Zhan ◽  
Carlos A. Pastore ◽  
Ryszard Piotrowicz ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Consensus Paper ◽  
Electrocardiographic Abnormalities

scholarly journals Long-term control of Chagas disease in Venezuela: effects on serologic findings, electrocardiographic abnormalities, and clinical outcome.

Circulation ◽  
1987 ◽  
Vol 76 (3) ◽  
pp. 556-562 ◽  
Author(s):  
H Acquatella ◽  
F Catalioti ◽  
J R Gomez-Mancebo ◽  
V Davalos ◽  
L Villalobos
Keyword(s):  
Clinical Outcome ◽  
Chagas Disease ◽  
Electrocardiographic Abnormalities

CARDIAC COMPLICATIONS OF DIPHTHERIA

PEDIATRICS ◽  
1963 ◽  
Vol 32 (4) ◽  
pp. 549-557
Author(s):  
Beverly C. Morgan
Keyword(s):  
Heart Block ◽  
Clinical Evidence ◽  
Complete Heart Block ◽  
Cardiac Complications ◽  
Respiratory Complications ◽  
Bundle Branch Block ◽  
Electrocardiographic Abnormalities

Ninety-eight cases of diphtheria were observed in a 5½ year period, and the cardiac findings were evaluated. There were nine deaths. Three patients were dead on arrival See Image in the PDF File at the hospital (without postmortem evidence of myocarditis) while three died of diphtheritic myocarditis and three as a result of respiratory complications. No child who succumbed had been immunized against diphtheria. Four patients developed electrocardiographic and clinical evidence of myocarditis, and three died. In addition, 27 children showed minor electrocardiographic abnormalities of questionable significance. No patient had clinical or pathological evidence of myocarditis in the absence of electrocardiographic abnormalities. Although transient nonspecific electrocardiorgaphic abnormalities are frequent, their significance remains unclear. Marked electrocardiographic abnormalities such as bundle-branch block, A-V dissociation, and complete heart block are diagnostic of myocarditis in patients with diphtheria.

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