Histopathological and apoptotic changes on marine mussels Mytilus galloprovincialis (Lamark, 1819) following exposure to environmental pollutants

2016 ◽  
Vol 109 (1) ◽  
pp. 184-191 ◽  
Author(s):  
Altuğ Yavaşoğlu ◽  
Dilara Özkan ◽  
Adem Güner ◽  
Selma Katalay ◽  
Fatih Oltulu ◽  
...  
Keyword(s):  
Mytilus Galloprovincialis ◽  
Environmental Pollutants ◽  
Marine Mussels

The role of fructose 2,6-bisphosphate in the regulation of marine mussels (Mytilus galloprovincialis and mytilus edulis) glycolysis/gluconeogenesis

1993 ◽  
Vol 104 (4) ◽  
pp. 641-647 ◽  
Author(s):  
Juan Ignacio Ramos-Martínez ◽  
JoséAntonio Villamarín ◽  
Ramiro Barcia ◽  
Maria Dolores Vazquez Illanes ◽  
Izaskun Ibarguren
Keyword(s):  
Mytilus Edulis ◽  
Mytilus Galloprovincialis ◽  
Marine Mussels

scholarly journals Morphological, Gene, and Hormonal Changes in Gonads and In-Creased Micrococcal Nuclease Accessibility of Sperm Chromatin Induced by Mercury

Biomolecules ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 87
Author(s):  
Gennaro Lettieri ◽  
Nadia Carusone ◽  
Rosaria Notariale ◽  
Marina Prisco ◽  
Alessia Ambrosino ◽  
...  
Keyword(s):  
Reproductive Health ◽  
Preliminary Data ◽  
Mytilus Galloprovincialis ◽  
Environmental Pollutants ◽  
Chromatin Accessibility ◽  
Micrococcal Nuclease ◽  
Sperm Chromatin ◽  
Hormonal Changes ◽  
Potential Toxicity ◽  
Stress Genes

Mercury is one of the most dangerous environmental pollutants. In this work, we analysed the effects of exposure of Mytilus galloprovincialis to 1, 10 and 100 pM HgCl2 for 24 h on the gonadal morphology and on the expression level of three stress genes: mt10, hsp70 and πgst. In this tissue we also evaluated the level of steroidogenic enzymes 3β-HSD and 17β-HSD and the expression of PL protein genes. Finally, we determined difference in sperm chromatin accessibility to micrococcal nuclease. We found alterations in gonadal morphology especially after exposure to 10 and 100 pM HgCl2 and hypo-expression of the three stress genes, particularly for hsp70. Furthermore, decreased labelling with both 3β-HSD and 17β-HSD antibodies was observed following exposure to 1 and 10 pM HgCl2 and complete absence at 100 pM HgCl2 exposure. Gonads of mussels exposed to all HgCl2 doses showed decreased expression of PL protein genes especially for PLIII. Finally, micrococcal nuclease digestions showed that all doses of HgCl2 exposure resulted in increased sperm chromatin accessibility to this enzyme, indicative of improper sperm chromatin structure. All of these changes provide preliminary data of the potential toxicity of mercury on the reproductive health of this mussel.

scholarly journals Antagonistic Interactions between Benzo[a]pyrene and C60 in Toxicological Response of Marine Mussels

2019 ◽  
Author(s):  
Audrey Barranger ◽  
Laura M. Langan ◽  
Vikram Sharma ◽  
Graham A. Rance ◽  
Yann Aminot ◽  
...  
Keyword(s):  
Mytilus Galloprovincialis ◽  
Kegg Pathway ◽  
Biological Processes ◽  
Single Exposure ◽  
Proteomics Analysis ◽  
Cellular Processes ◽  
Kegg Pathway Analysis ◽  
Icp Ms ◽  
Marine Mussels ◽  
Environmental Information Processing

This study aimed to assess the ecotoxicological effects of the interaction of fullerene (C60) and benzo[a]pyrene (B[a]P) on the marine mussel, Mytilus galloprovincialis. The uptake of nC60, B[a]P and mixtures of nC60 and B[a]P into tissues was confirmed by GC-MS, LC-HRMS and ICP-MS. Biomarkers of DNA damage as well as proteomics analysis were applied to unravel the toxic effect of B[a]P and C60. Antagonistic responses were observed at the genotoxic and proteomic level. Differentially expressed proteins (DEPs) were only identified in the B[a]P single exposure and the B[a]P mixture exposure groups containing 1 mg/L of C60, the majority of which were down-regulated (~52%). No DEPs were identified at any of the concentrations of nC60 (p < 0.05, 1% FDR). Using DEPs identified at a threshold of (p < 0.05; B[a]P and B[a]P mixture with nC60), gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis indicated that these proteins were enriched with a broad spectrum of biological processes and pathways, including those broadly associated with protein processing, cellular processes and environmental information processing. Among those significantly enriched pathways, the ribosome was consistently the top enriched term irrespective of treatment or concentration and plays an important role as the site of biological protein synthesis and translation. Our results demonstrate the complex multi-modal response to environmental stressors in M. galloprovincialis.

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