Electrospun fibers of layered double hydroxide/biopolymer nanocomposites as effective drug delivery systems

2012 ◽  
Vol 134 (2-3) ◽  
pp. 623-630 ◽  
Author(s):  
Yue-E. Miao ◽  
Hong Zhu ◽  
Dan Chen ◽  
Ruiyu Wang ◽  
Weng Weei Tjiu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Layered Double Hydroxide ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Effective Drug ◽  
Electrospun Fibers ◽  
Double Hydroxide

Polymer nanofibers for biomedical applications: advances by electrospinning

2021 ◽  
Vol 04 ◽  
Author(s):  
Anna L.M.M. Toledo ◽  
Talita N. da Silva ◽  
Arianne C. dos S. Vaucher ◽  
Arthur H. V. Miranda ◽  
Gabriela C. C. Silva de Miranda ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
New Technologies ◽  
Low Cost ◽  
Electrospun Nanofibers ◽  
Delivery Systems ◽  
Electrospun Fibers ◽  
Sustained Delivery ◽  
Biomedical Devices ◽  
Ultrathin Fibers

Background: The demand for novel biomaterials has been exponentially rising in the last years as well as the searching for new technologies able to produce more efficient products in both drug delivery systems and regenerative medicine. Objective: The technique that can pretty well encompass the needs for novel and high-end materials with a relatively low-cost and easy operation is the electrospinning of polymer solutions. Methods: Electrospinning usually produces ultrathin fibers that can be applied in a myriad of biomedical devices including sustained delivery systems for drugs, proteins, biomolecules, hormones, etc that can be applied in a broad spectrum of applications, from transdermal patches to cancer-related drugs. Results: Electrospun fibers can be produced to mimic certain tissues of the human body, being an option to create new scaffolds for implants with several advantages. Conclusions: In this review, we aimed to encompass the use of electrospun fibers in the field of biomedical devices, more specifically in the use of electrospun nanofibers applications toward the production of drug delivery systems and scaffolds for tissue regeneration.

New organic/inorganic nanohybrids of targeted pullulan derivative/gold nanoparticles for effective drug delivery systems

2020 ◽  
Vol 162 ◽  
pp. 561-577 ◽  
Author(s):  
Sakchai Laksee ◽  
Kanokwan Sansanaphongpricha ◽  
Songchan Puthong ◽  
Naunpun Sangphech ◽  
Tanapat Palaga ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Effective Drug

scholarly journals A Review on Nanocarriers for Cancer Targeted Drug Delivery

2020 ◽  
Vol 63 (3) ◽  
pp. 239-246
Author(s):  
Fariha Lrfan ◽  
Tahir Lqbal ◽  
Nafisa Malik ◽  
Mohsin Ljaz
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Drug Carriers ◽  
Delivery Systems ◽  
Effective Drug ◽  
Targeted Drug

Nanoparticles in the drugs are useful for the treatment of cancer due to their unique properties and can act as drug carriers in different ways. Unlike the traditional chemotherapy, the entrance of nanotechnology enabled wide applications in treatment of cancer. Although nanoparticles provides safe and effective drug delivery systems but the factor of toxicity still limits the utilisation of several nanoparticles. The properties of nanodrug carriers are controllable by various factors. The use of nanoparticles in cancer therapy by drug delivery and their advantages as been reviewed.      

scholarly journals The Advances of Neutrophil-Derived Effective Drug Delivery Systems: A Key Review of Managing Tumors and Inflammation

2021 ◽  
Vol Volume 16 ◽  
pp. 7663-7681
Author(s):  
Huaiji Wang ◽  
Jie Zang ◽  
Zihan Zhao ◽  
Qin Zhang ◽  
Shunjie Chen
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Effective Drug

scholarly journals Novel approaches in development of cell penetrating peptides

2021 ◽  
Vol 9 (1) ◽  
pp. 1-7
Author(s):  
Vatsal R. Shah ◽  
Yamini D. Shah ◽  
Mansi N. Athalye
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Drug Delivery Systems ◽  
Cell Penetrating Peptides ◽  
Delivery Systems ◽  
Endosomal Escape ◽  
Effective Drug ◽  
Cell Penetrating ◽  
Potential Benefits ◽  
Novel Approaches

Therapeutic cargos which are impermeable to the cell can be delivered by cell penetrating peptides (CPPs). CPP-cargo complexes accumulate by endocytosis inside the cells but they fail to reach the cytosolic space properly as they are often trapped in the endocytic organelles. Here the CPP mediated endosomal escape and some strategies used to increase endosomal escape of CPP-cargo conjugates are discussed with evidence. Potential benefits can be obtained by peptides such as reduction in side effects, biocompatibility, easier synthesis and can be obtained at lower administered doses. The particular peptide known as cell penetrating peptides are able to translocate themselves across membrane with the carrier drugs with different mechanisms. This is of prime importance in drug delivery systems as they have capability to cross physiological membranes. This review describes various mechanisms for effective drug delivery and associated challenges

Sign in / Sign up

Export Citation Format

Share Document