Building blocks to the future of regenerative medicine: Organoid bioprinting

Matter ◽  
2021 ◽  
Vol 4 (8) ◽  
pp. 2659-2661
Author(s):  
Nathanael Tan ◽  
Yi Yan Yang
2010 ◽  
Vol 7 (suppl_6) ◽  
Author(s):  
Robert M. Nerem

Over the last quarter of a century there has been an emergence of a tissue engineering industry, one that has now evolved into the broader area of regenerative medicine. There have been ‘ups and downs’ in this industry; however, it now appears to be on a track that may be described as ‘back to the future’. The latest data indicate that for 2007 the private sector activity in the world for this industry is approaching $2.5 billion, with 167 companies/business units and more than 6000 employee full time equivalents. Although small compared with the medical device and also the pharmaceutical industries, these numbers are not insignificant. Thus, there is the indication that this industry, and the related technology, may still achieve its potential and address the needs of millions of patients worldwide, in particular those with needs that currently are unmet.


2018 ◽  
Vol 2 (1) ◽  
pp. 1-37
Author(s):  
F. Bocken ◽  
E. Brennan ◽  
N. Claessens ◽  
D. Claeys ◽  
S. Debeaussaert ◽  
...  

Abstract Contemporary society is plagued by a number of issues and inconsistencies on both an environmental and a socio-economic level. Reliance on bank loans forces debtors to seek means to repay their debts, thus facilitating the current boundless economic growth in which long-term, environmental considerations typically come second. On the individual level, since virtually nothing is free, everyone has to ensure his or her own livelihood, mostly in the form of wage labour. For fear of poverty, the unemployed must adjust to the needs of the job market and risk not being able to fully explore their potential. Other socio-economic groups also face stigmatisation, and inequality is rampant as a result of the pervasive market-based pricing mechanisms. In view of these issues, it seems unjustified to accept these terms and conditions in the future, especially since the West has to cater to its ageing population and the ensuing pressure this will exert on welfare systems. Therefore, as a transdisciplinary team assisted by various experts and armed with insights from a wide <target target-type="page-num" id="p-2"/>variety of sources, we propose an alternative model of society based on the values of fairness, inclusion and transparency, with the goal of developing a representative systems map for a future, resilient and equitable society. The exact workings of this society are captured by several building blocks, which together endeavour to cover the full range of functions and responsibilities associated with society today, and jointly promote democratisation while guaranteeing equal political representation for all members of society.


2021 ◽  
Vol 18 ◽  
Author(s):  
Antoine Michaut ◽  
Sabrina Quatrevaux ◽  
Laurence Queguiner ◽  
Sandrine Gaurrand ◽  
Jérôme Guillemont

Abstract: The synthesis of advanced substituted 3-pentafluorosulfanylphenol/anisole was accomplished starting from the easy to access and commercially available 3-pentafluorosulfanylphenol. These products bear diverse substitutions such as ester, aldehyde, halogens, alcohol, nitrile and carboxylic acid and could be in the future used as high value building blocks for the synthesis of various scaffolds. For our part, this intermediate had been used to synthetize a library of 2-arylindadiones substituted by a pentafluorosulfanyl group.


2017 ◽  
Vol 8 (4) ◽  
pp. 34-74
Author(s):  
Abdulkader Alfantookh ◽  
Saad Haj Bakry

The Gulf Cooperation Council (GCC) countries, with their rich oil resources, are facing the problem of fallen oil prices on the one hand, and reduced oil reserves on the other. As a result, they are moving toward less dependence on oil, and increasing dependence on people and knowledge. This paper develops a wide scope “people and knowledge index (PKI)” using relevant international indicators made available by various international organizations. The index includes “ten building blocks.” Four of these blocks are concerned with the “core issues” of people and knowledge; while the other six blocks are related to the “environment issues” according to which people and knowledge interact. The paper assesses the GCC countries according to the index revealing their strengths and weaknesses, and enabling the derivation of guidelines for their future development. The resulting guidelines consider how the GCC countries can direct their future development toward a high and growing standard of living, while reducing dependence on oil. Finally, the future use of the new index is highlighted.


2019 ◽  
Vol 41 (4) ◽  
pp. 12-15
Author(s):  
Kit Chapman

Abstract When Dimitri Mendeleev assembled his periodic table in 1869, the heaviest known element was uranium, element 92. As the table filled, it soon became clear that this was the heaviest element that existed in large quantities on Earth. But it was far from the limit of the building blocks of matter.


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