Amyloid-β Precursor Protein Processing and Oxidative Stress are Altered in Human iPSC-Derived Neuron and Astrocyte Co-Cultures Carrying Presenillin-1 Gene Mutations Following Spontaneous Differentiation

2021 ◽  
pp. 103631
Author(s):  
Richard J. Elsworthy ◽  
Marianne C. King ◽  
Alastair Grainger ◽  
Emily Fisher ◽  
James A. Crowe ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Mutations ◽  
Amyloid Β ◽  
Protein Processing ◽  
Precursor Protein ◽  
Spontaneous Differentiation ◽  
Human Ipsc ◽  
And Oxidative Stress

scholarly journals Effects of Huanglian-Jie-Du-Tang and Its Modified Formula on the Modulation of Amyloid-β Precursor Protein Processing in Alzheimer's Disease Models

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e92954 ◽  
Author(s):  
Siva Sundara Kumar Durairajan ◽  
Ying-Yu Huang ◽  
Pui-Yee Yuen ◽  
Lei-Lei Chen ◽  
Ka-Yan Kwok ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Β ◽  
Protein Processing ◽  
Precursor Protein ◽  
Disease Models ◽  
Modified Formula

scholarly journals Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production

2017 ◽  
Vol 292 (9) ◽  
pp. 3751-3767 ◽  
Author(s):  
Hermeto Gerber ◽  
Fang Wu ◽  
Mitko Dimitrov ◽  
Guillermo M. Garcia Osuna ◽  
Patrick C. Fraering
Keyword(s):  
Amyloid Precursor Protein ◽  
Amyloid Β ◽  
Protein Processing ◽  
Precursor Protein ◽  
Amyloid Precursor Protein Processing ◽  
Amyloid Β Peptide

scholarly journals A cellular model of amyloid precursor protein processing and amyloid-β peptide production

2014 ◽  
Vol 223 ◽  
pp. 114-122 ◽  
Author(s):  
MiMi P. Macias ◽  
Amanda M. Gonzales ◽  
Ashley L. Siniard ◽  
Aaron W. Walker ◽  
Jason J. Corneveaux ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Amyloid Β ◽  
Protein Processing ◽  
Precursor Protein ◽  
Amyloid Precursor Protein Processing ◽  
Amyloid Β Peptide ◽  
Cellular Model

scholarly journals Benzothiazole Amphiphiles Ameliorate Amyloid β-Related Cell Toxicity and Oxidative Stress

2016 ◽  
Vol 7 (6) ◽  
pp. 682-688 ◽  
Author(s):  
Jessica L. Cifelli ◽  
Tim S. Chung ◽  
Haiyan Liu ◽  
Panchika Prangkio ◽  
Michael Mayer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Amyloid Β ◽  
Cell Toxicity ◽  
Related Cell ◽  
And Oxidative Stress
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