Protective role of ETA endothelin receptors during the acute phase of Trypanosoma cruzi infection in rats

2004 ◽  
Vol 6 (7) ◽  
pp. 650-656 ◽  
Author(s):  
Elizabeth R.S. Camargos ◽  
Lamara L.V. Rocha ◽  
Milene A. Rachid ◽  
Alvair P. Almeida ◽  
Anderson J. Ferreira ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Acute Phase ◽  
Protective Role ◽  
Endothelin Receptors ◽  
Cruzi Infection

scholarly journals Role of endothelin receptors in the control of central nervous system parasitism in Trypanosoma cruzi infection in rats

2010 ◽  
Vol 220 (1-2) ◽  
pp. 64-68 ◽  
Author(s):  
Milene A. Rachid ◽  
Antônio L. Teixeira ◽  
Lucíola S. Barcelos ◽  
Conceição R.S. Machado ◽  
Egler Chiari ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Trypanosoma Cruzi ◽  
Endothelin Receptors ◽  
Cruzi Infection

scholarly journals Protective Role of Acetylsalicylic Acid in Experimental Trypanosoma cruzi Infection: Evidence of a 15-epi-Lipoxin A4-Mediated Effect

2013 ◽  
Vol 7 (4) ◽  
pp. e2173 ◽  
Author(s):  
Alfredo Molina-Berríos ◽  
Carolina Campos-Estrada ◽  
Natalia Henriquez ◽  
Mario Faúndez ◽  
Gloria Torres ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Acetylsalicylic Acid ◽  
Protective Role ◽  
Lipoxin A4 ◽  
Cruzi Infection

scholarly journals Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection

2020 ◽  
Vol 119 (6) ◽  
pp. 1845-1845
Author(s):  
Paul Zaki ◽  
Elisa L. B. C. Domingues ◽  
Farhad M. Amjad ◽  
Maiara B. Narde ◽  
Karolina R. Gonçalves ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Mouse Models ◽  
Cruzi Infection

ACUTE PHASE REACTIONS AFTER ZOLEDRONIC ACID INFUSION: PROTECTIVE ROLE OF 25-HYDROXYVITAMIN D AND PREVIOUS ORAL BISPHOSPHONATE THERAPY

2018 ◽  
Vol 24 (5) ◽  
pp. 405-410 ◽  
Author(s):  
Chiara Crotti ◽  
Nelson B. Watts ◽  
Maria De Santis ◽  
Angela Ceribelli ◽  
Gianluigi Fabbriciani ◽  
...  
Keyword(s):  
Zoledronic Acid ◽  
Acute Phase ◽  
Protective Role ◽  
Bisphosphonate Therapy ◽  
Acid Infusion ◽  
Hydroxyvitamin D ◽  
Oral Bisphosphonate ◽  
25 Hydroxyvitamin D ◽  
Acute Phase Reactions

Cytokine modulation, oxidative stress and thymic dysfunctions: Role of age-related changes in the experimental Trypanosoma cruzi infection

Cytokine ◽  
2018 ◽  
Vol 111 ◽  
pp. 88-96 ◽  
Author(s):  
Rafaela Pravato Colato ◽  
Vânia Brazão ◽  
Gabriel Tavares do Vale ◽  
Fabricia Helena Santello ◽  
Pedro Alexandre Sampaio ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Trypanosoma Cruzi ◽  
Cytokine Modulation ◽  
Age Related ◽  
Cruzi Infection ◽  
Age Related Changes

scholarly journals Evolution of subpatent parasitaemia in Trypanosoma cruzi chronically infected mice with the help of a cyclophosphamide amplification transfer assay

1991 ◽  
Vol 33 (6) ◽  
pp. 509-514 ◽  
Author(s):  
José M. Alvarez ◽  
Ayumi Oshima ◽  
Veronica Mozer ◽  
Liliane Guimarães ◽  
Hércules Menezes
Keyword(s):  
Trypanosoma Cruzi ◽  
Acute Phase ◽  
Chronic Phase ◽  
Detection Tool ◽  
Highly Sensitive ◽  
Parasite Detection ◽  
Cyclophosphamide Treatment ◽  
One Year ◽  
Cruzi Infection

We have evaluated the sensitivity of the classical blood subinoculation method, modified through cyclophosphamide treatment of transferred mice, for the detection of occult parasitaemias in Trypanosoma cruzi chronically infected mice. Besides its simplicity, the method was shown to be highly sensitive for both the "chronic" phase parasites (99% of chronic cases were shown to harbour occult parasitaemias) and for the acute phase parasites (T. cruzi could be detected in 53.8% of animals transferred with one Y strain parasite and in 20% of animals transferred with one CL strain parasite). Using acute phase bloodforms, the assay proved to be more sensitive than conventional subinoculation when dealing with the CL, but not the Y strain of the parasite. With the help of this parasite detection tool, we have studied during a one year period, the evolution of subpatent parasitaemias in a group of mice which survived through chemotherapy from lethal acute phase of T. cruzi infection. Cyclophosphamide transfer assay revealed occult parasitaemias in 100% of the chronic animals, nevertheless, continuous and discontinuous patterns of positivity were observed.

scholarly journals New evidence of spontaneous cure in human Chagas' disease

2003 ◽  
Vol 36 (1) ◽  
pp. 103-107 ◽  
Author(s):  
Sonia S. Francolino ◽  
Antonio Fernandez Antunes ◽  
Rodolfo Talice ◽  
Rachel Rosa ◽  
Joel Selanikio ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Trypanosoma Cruzi ◽  
Chagas Disease ◽  
Acute Phase ◽  
Clinical Data ◽  
Specific Treatment ◽  
Serological Tests ◽  
Spontaneous Cure ◽  
New Evidence ◽  
Cruzi Infection

A new case of spontaneous cure of human Chagas' disease is described in Uruguay. An 87-year-old man who had a typical acute phase of Trypanosoma cruzi infection in 1947 and never received specific treatment against the disease, when examined in 1998 revealed several completely negative parasitological and serological tests, including traditional serology, PCR and flow cytometry. As a whole, such findings fulfill the current criteria to define the cure of Chagas' disease. Clinical data suggest the possibility of a benign evolution of Chagas' disease in this case, but the basic findings (slight cardiac and esophageal impairment) could also be due to the advanced age of the patient.

scholarly journals Trypanosoma cruzi Evades the Protective Role of Interferon-Gamma-Signaling in Parasite-Infected Cells

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e110512 ◽  
Author(s):  
Philipp Stahl ◽  
Volker Ruppert ◽  
Ralph T. Schwarz ◽  
Thomas Meyer
Keyword(s):  
Trypanosoma Cruzi ◽  
Interferon Gamma ◽  
Protective Role ◽  
Infected Cells
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