MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Mek Inhibitors ◽

Acquired Resistance of Non-Small Cell Lung Cancer Cells to MET Kinase Inhibition Is Mediated by a Switch to Epidermal Growth Factor Receptor Dependency

Cancer Research ◽

10.1158/0008-5472.can-09-3620 ◽

2010 ◽

Vol 70 (4) ◽

pp. 1625-1634 ◽

Cited By ~ 108

Author(s):

U. McDermott ◽

R. V. Pusapati ◽

J. G. Christensen ◽

N. S. Gray ◽

J. Settleman

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Abstract 5542: Activation of epidermal growth factor receptor potentiates effects of radiation in A549 lung cancer cells

10.1158/1538-7445.am10-5542 ◽

2010 ◽

Author(s):

Seema Gupta ◽

Chandra Childress ◽

Mansoor M. Ahmed ◽

Wannian Yang

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Epidermal Growth ◽

Effects Of Radiation ◽

A549 Lung

Abstract 4401: A novel drug suppresses proliferation of lung cancer cells via increasing the CBL activity and down-regulating epidermal growth factor receptor

10.1158/1538-7445.am2014-4401 ◽

2014 ◽

Author(s):

Kuo-Yen Huang ◽

Szu-Hua Pan ◽

Wen-Lung Wang ◽

Ching-Shih Chen ◽

Tse-Ming Hong ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Epidermal Growth ◽

Novel Drug

Synergistic Antitumor Activity of Sorafenib in Combination with Epidermal Growth Factor Receptor Inhibitors in Colorectal and Lung Cancer Cells

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-10-0923 ◽

2010 ◽

Vol 16 (20) ◽

pp. 4990-5001 ◽

Cited By ~ 63

Author(s):

Erika Martinelli ◽

Teresa Troiani ◽

Floriana Morgillo ◽

Gabriella Rodolico ◽

Donata Vitagliano ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Antitumor Activity ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Epidermal Growth ◽

Synergistic Antitumor Activity

A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2008.07.004 ◽

2009 ◽

Vol 41 (3) ◽

pp. 603-614 ◽

Cited By ~ 44

Author(s):

Anna Grazia Recchia ◽

Anna Maria Musti ◽

Marilena Lanzino ◽

Maria Luisa Panno ◽

Ermanna Turano ◽

...

Keyword(s):

Lung Cancer ◽

Androgen Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Cross Talk ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

E7080 Suppresses Hematogenous Multiple Organ Metastases of Lung Cancer Cells with Nonmutated Epidermal Growth Factor Receptor

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-10-0707 ◽

2011 ◽

Vol 10 (7) ◽

pp. 1218-1228 ◽

Cited By ~ 11

Author(s):

Hirokazu Ogino ◽

Masaki Hanibuchi ◽

Soji Kakiuchi ◽

Van The Trung ◽

Hisatsugu Goto ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Multiple Organ ◽

Lung Cancer Cells ◽

YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells

PLoS ONE ◽

10.1371/journal.pone.0182149 ◽

2017 ◽

Vol 12 (8) ◽

pp. e0182149 ◽

Cited By ~ 14

Author(s):

Chun-Chia Cheng ◽

Jungshan Chang ◽

Stanley Ching-Cheng Huang ◽

Huan-Chau Lin ◽

Ai-Sheng Ho ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Cancer Stemness ◽

The insulin-like growth factor 1 receptor causes acquired resistance to erlotinib in lung cancer cells with the wild-type epidermal growth factor receptor

International Journal of Cancer ◽

10.1002/ijc.28737 ◽

2014 ◽

Vol 135 (4) ◽

pp. 1002-1006 ◽

Cited By ~ 27

Author(s):

Kenichi Suda ◽

Hiroshi Mizuuchi ◽

Katsuaki Sato ◽

Toshiki Takemoto ◽

Takuya Iwasaki ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Acquired Resistance ◽

Growth Factor Receptor ◽

Insulin Like Growth Factor ◽

Wild Type ◽

Dasatinib (BMS-354825) Selectively Induces Apoptosis in Lung Cancer Cells Dependent on Epidermal Growth Factor Receptor Signaling for Survival

Cancer Research ◽

10.1158/0008-5472.can-05-4620 ◽

2006 ◽

Vol 66 (11) ◽

pp. 5542-5548 ◽

Cited By ~ 148

Author(s):

Lanxi Song ◽

Mark Morris ◽

Tapan Bagui ◽

Francis Y. Lee ◽

Richard Jove ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Receptor Signaling ◽

Epidermal Growth ◽

Growth Factor Receptor Signaling

Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathways Resulting in Enhanced Therapeutic Efficacy

PLoS ONE ◽

10.1371/journal.pone.0123967 ◽

2015 ◽

Vol 10 (6) ◽

pp. e0123967 ◽

Cited By ~ 13

Author(s):

Bingbing Dai ◽

Shaoyu Yan ◽

Humberto Lara-Guerra ◽

Hiroyuki Kawashima ◽

Ryo Sakai ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Cells ◽

Therapeutic Efficacy ◽

Growth Factor Receptor ◽

Lung Cancer Cells ◽

Epidermal Growth ◽

Context Specific