DNA interaction with octahedral and square planar Ni(II) complexes of aspartic-acid Schiff-bases

2011 ◽  
Vol 1006 (1-3) ◽  
pp. 272-281 ◽  
Author(s):  
S.A. Sallam ◽  
A.S. Orabi ◽  
A.M. Abbas
Author(s):  
Cleiton M. da Silva ◽  
Marina M. Silva ◽  
Fabiano S. Reis ◽  
Ana Lúcia T.G. Ruiz ◽  
João E. de Carvalho ◽  
...  

1985 ◽  
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A. Ceulemans ◽  
M. Dendooven ◽  
L. G. Vanquickenborne

2013 ◽  
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Nan Zhang ◽  
Yu-Hua Fan ◽  
Cai-Feng Bi ◽  
Jian Zuo ◽  
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2012 ◽  
Vol 9 (3) ◽  
pp. 1422-1430
Author(s):  
Lijun Li ◽  
Chao Tian ◽  
Cheng Wang ◽  
Guangyuan Wang ◽  
Lianzeng Wang ◽  
...  

Five sterically hindered platinum(II) complexes with tetradentate schiff bases as ligands, [Pt(L)] (L=N,N′-bisalicylidene-1,2-ethylenediamine (L1),N,N′-bisalicylidene-1,2-cyclohexanediamine (L2), N,N′-bis(5-hydroxyl-salicylidene)-1,2-cyclohexanediamine (L3),N,N′-bisalicylidene-1,2-diphenyl-ethylenediamine (L4) andN,N′-bis(3-tert-butyl-5-methyl-salicylidene)-1,2-diphenylethylenediamine (L5) ) have been synthesized and characterized by IR spectroscopy and elemental analysis. The sterical hindrance of antitumor drug candidates potentially makes them less susceptible to deactivation by sulphur containing proteins and helping to overcome resistance mechanisms. The interaction of these metal complexes with fish sperm single-stranded DNA (ssDNA) was studied electrochemically based on the oxidation signals of guanine and adenine. Differential pulse voltammetry was employed to monitor the DNA interaction in solution by using renewable pencil graphite electrode. The results indicate that ligands with different groups can strongly affect the interaction between [Pt(L)] complexes and ssDNA due to sterical hindrances and complex [Pt(L1)] has the best interaction with DNA among the five complexes.


2017 ◽  
Vol 833 ◽  
pp. 18-27 ◽  
Author(s):  
Muhammed Bilaal Ismail ◽  
Irvin Noel Booysen ◽  
Matthew Piers Akerman ◽  
Craig Grimmer

2017 ◽  
Vol 838 ◽  
pp. 24-36 ◽  
Author(s):  
Tushar S. Basu Baul ◽  
Pelesakuo Kehie ◽  
Andrew Duthie ◽  
Herbert Höpfl

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